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2-bromo-5-methyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one

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Identification
Molecular formula
C18H17BrN2O
CAS number
150322-43-3
IUPAC name
2-bromo-5-methyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one
State
State
Solid at room temperature, typically handled in powdered or crystalline form.
Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
536.00
Boiling point (Kelvin)
809.15
General information
Molecular weight
358.27g/mol
Molar mass
358.2680g/mol
Density
1.6150g/cm3
Appearence
2-Bromo-5-methyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one typically appears as a crystalline solid with a pale yellow to off-white color. Its exact appearance may vary slightly based on purity and form.
Comment on solubility

Solubility of 2-bromo-5-methyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one

The solubility of 2-bromo-5-methyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one can be quite complex due to its intricate molecular structure.

Some key points regarding its solubility include:

  • Polarity: The presence of the bromine atom likely contributes to variations in polarity, affecting solubility in polar versus non-polar solvents.
  • Solvent interactions: This compound may show higher solubility in organic solvents such as ethanol or chloroform compared to water, due to hydrophobic characteristics from its extensive hydrocarbon framework.
  • Hydrogen bonding: The carbonyl group in the structure may also participate in hydrogen bonding, which can further influence solubility in various solvents.

In summary, while specific solubility data may not be readily available, it is essential to consider the compound's structural features which indicate that it is likely soluble in organic solvents, but less so in aqueous environments. As always, experimental solubility tests should be performed for accurate assessments.

Interesting facts

Interesting Facts about 2-bromo-5-methyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one

The compound 2-bromo-5-methyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one belongs to a fascinating class of chemical compounds known as benzodiazepines, which are primarily recognized for their psychoactive effects. Here are some interesting facts about this compound:

  • Structure Complexity: The intricate structure of this compound includes multiple fused rings, contributing to its potential bioactivity and versatility in medicinal chemistry.
  • Pharmacological Relevance: Compounds of similar structure are often evaluated for their therapeutic properties, particularly in the treatment of anxiety, insomnia, and other central nervous system disorders.
  • Bridging Chemical Classes: This compound uniquely bridges the isoquinoline and benzodiazepine classes, which could lead to interesting interactions and effects different from typical benzodiazepines.
  • Potential Research Application: The presence of the bromine atom suggests that substitution might affect the compound’s reactivity and interaction with biological targets, making it a subject of interest for synthesis and modification in laboratories.
  • Synthetic Pathways: The complexity of synthesizing such a compound not only poses challenges but also encourages innovative approaches in organic synthesis, promoting the development of new methodologies.

In the words of a notable chemist, “The beauty of chemistry lies in its ability to transform simple building blocks into complex structures that can have profound effects.” Understanding compounds like 2-bromo-5-methyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one offers insights into the rich possibilities in both the realms of pharmaceuticals and synthetic chemistry. The exploration of such compounds can potentially lead to breakthroughs in drug design and therapeutic applications.

Synonyms
19007-20-6
BRN 3993658
2-Bromo-5-methyl-6,7,9,10-tetrahydro-5H-isoquino(2,1-d)(1,4)benzodiazepin-6-one
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-bromo-5-methyl-
2-bromo-5-methyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one
2-Bromo-5,9,10,14b-tetrahydro-5-methylisoquino[2,1-d][1,4]benzodiazepin-6(7H)-one
DTXSID30940541
2-Bromo-5-methyl-5,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6(7H)-one