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2-Bromo-6-chlorophenol

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Identification
Molecular formula
C6H4BrClO
CAS number
136-00-1
IUPAC name
2-bromo-6-chloro-phenol
State
State

At room temperature, 2-Bromo-6-chlorophenol exists as a solid.

Melting point (Celsius)
58.00
Melting point (Kelvin)
331.15
Boiling point (Celsius)
276.00
Boiling point (Kelvin)
549.15
General information
Molecular weight
207.45g/mol
Molar mass
207.4480g/mol
Density
1.8700g/cm3
Appearence

2-Bromo-6-chlorophenol typically appears as a solid crystalline substance. It is often characterized by a white to off-white color.

Comment on solubility

Solubility of 2-bromo-6-chloro-phenol

2-bromo-6-chloro-phenol, a compound with the formula C6H4BrClO, exhibits notable solubility characteristics that are influenced by both its molecular structure and functional groups.

Solubility Insights

Here are some key points regarding the solubility of this compound:

  • Polar Nature: The presence of both bromine and chlorine atoms enhances the polar characteristics of this molecule, making it more likely to dissolve in polar solvents.
  • Solvent Compatibility: 2-bromo-6-chloro-phenol is soluble in a variety of organic solvents, including ethanol and methanol, while showing less solubility in nonpolar solvents such as hexane.
  • Hydrogen Bonding: The hydroxyl (-OH) group can engage in hydrogen bonding, increasing its solubility in water to a certain extent, although it is not highly soluble compared to other phenolic compounds.

Overall, while it showcases reasonable solubility in polar solvents, one might find that its overall solubility is moderate when compared to simpler phenolic compounds. This compound serves as an interesting example of how halogen substitutions can influence solubility properties in organic chemistry.

Interesting facts

Interesting Facts About 2-Bromo-6-chloro-phenol

2-Bromo-6-chloro-phenol is a fascinating compound that plays a significant role in various chemical applications. Here are some noteworthy points about this intriguing compound:

  • Structural Significance: The combination of bromine and chlorine atoms in its structure makes 2-bromo-6-chloro-phenol a valuable reactive intermediate in organic synthesis. These halogens can influence the reactivity and properties of the compound in exciting ways.
  • Medicinal Chemistry: Compounds like 2-bromo-6-chloro-phenol are often studied for their potential pharmaceutical applications. They can act as antimicrobial agents and are used in the development of drugs that fight infections.
  • Environmental Impact: Understanding the behavior of halogenated phenols is crucial in environmental chemistry. Some chlorinated and brominated compounds can persist in the environment, leading to concerns regarding their biodistribution and biodegradation.
  • Applications in Research: 2-Bromo-6-chloro-phenol serves as a reagent in various chemical reactions, including coupling reactions and as a starting material for synthesizing more complex organic molecules.
  • Historical Context: Phenols, including halogenated derivatives like 2-bromo-6-chloro-phenol, have a long history in both industry and academia. Understanding their properties has been essential in evolving chemical research and manufacturing processes.

As a result of its versatile nature and applications, 2-bromo-6-chloro-phenol remains an important compound in the chemical sciences, particularly in the realms of organic synthesis and medicinal chemistry.

Synonyms
2-Bromo-6-chlorophenol
2040-88-2
Phenol, 2-bromo-6-chloro-
DTXSID40174350
DTXCID6096841
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MFCD09907875
SCHEMBL2018126
LUECOFFMVWPWDR-UHFFFAOYSA-N
AKOS016001419
CS-W018857
MB08152
AC-28473
DA-18438
FB141592
SY034449
EN300-199809
Z1269200416