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2-bromo-N-(2-tert-butyl-6-methyl-phenyl)-N-(methoxymethyl)acetamide

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Identification
Molecular formula
C15H22BrNO2
CAS number
118292-11-2
IUPAC name
2-bromo-N-(2-tert-butyl-6-methyl-phenyl)-N-(methoxymethyl)acetamide
State
State
At room temperature, it is found in a solid state, appearing as a crystalline powder.
Melting point (Celsius)
119.00
Melting point (Kelvin)
392.15
Boiling point (Celsius)
384.15
Boiling point (Kelvin)
657.30
General information
Molecular weight
315.21g/mol
Molar mass
315.2090g/mol
Density
1.2570g/cm3
Appearence

2-bromo-N-(2-tert-butyl-6-methyl-phenyl)-N-(methoxymethyl)acetamide is typically a white or off-white crystalline solid. The compound is known for its stable crystalline structure.

Comment on solubility

Solubility of 2-bromo-N-(2-tert-butyl-6-methyl-phenyl)-N-(methoxymethyl)acetamide

The solubility of 2-bromo-N-(2-tert-butyl-6-methyl-phenyl)-N-(methoxymethyl)acetamide is influenced by several factors, including its molecular structure and the nature of its functional groups. Understanding how such a compound dissolves in various solvents can provide insight into its behavior in different environments.

Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups, such as the acetamide and methoxymethyl groups, suggests some degree of solubility in polar solvents like water.
  • Hydrophobicity: The tert-butyl and bromine groups contribute to hydrophobic characteristics, potentially reducing solubility in aqueous solutions.
  • Temperature: Increased temperature generally increases the solubility of solids in liquids; thus, higher temperatures might enhance the dissolution rate of this compound.

In organic solvents such as ethanol or dimethyl sulfoxide (DMSO), the compound is likely to exhibit better solubility due to a favorable interaction between the solvent and the hydrophobic regions of the molecule. Conversely, in strictly nonpolar solvents, its solubility may be limited.

As a general takeaway, where solubility is concerned, it can be summarised as follows:

  • Good solubility in polar organic solvents.
  • Moderate to low solubility in water depending on temperature and pH.
  • Enhanced solubility with increased temperature.

Overall, the unique structural attributes of 2-bromo-N-(2-tert-butyl-6-methyl-phenyl)-N-(methoxymethyl)acetamide create a complex solubility profile that invites further investigation for applications in fields such as pharmaceuticals or materials science.

Interesting facts

Interesting Facts about 2-bromo-N-(2-tert-butyl-6-methyl-phenyl)-N-(methoxymethyl)acetamide

The compound 2-bromo-N-(2-tert-butyl-6-methyl-phenyl)-N-(methoxymethyl)acetamide is a fascinating example of a halogenated amide with intricate structural features. This compound highlights the interplay between chemical structure and biological activity, making it an interesting subject of study.

Key Attributes

  • Halogen Incorporation: The presence of the bromine atom significantly influences its chemical reactivity and potential applications in medicinal chemistry.
  • Amide Functionalization: The amide group plays a crucial role in solubility and the ability to participate in various chemical reactions, including peptide bond formation.
  • Bulky Groups: The tert-butyl and methyl groups impart steric hindrance, affecting the compound’s conformation and biological interactions.

This compound is often synthesized through complex organic reactions, showcasing the beauty and challenge of organic synthesis. As a scientist, it is essential to explore various reaction pathways and stereochemical outcomes to fully appreciate this compound's potential.

Potential Applications

The exploration of compounds like 2-bromo-N-(2-tert-butyl-6-methyl-phenyl)-N-(methoxymethyl)acetamide can lead to:

  • Pharmaceutical Development: Its unique structure may exhibit specific biological activities, making it a candidate for new drug discovery.
  • Research in Organic Chemistry: Studying its reaction mechanisms can contribute to a better understanding of amide chemistry.

In the world of organic chemistry, compounds such as this one demonstrate the intricate balance between structure and function. As scientists continue to explore their properties, the potential for discovering novel applications remains vast and exciting.

Synonyms
2-Bromo-6'-(t-butyl)-N-(methoxymethyl)-O-acetamide
2163-81-7
SCHEMBL9613901
DTXSID30176020