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Carvedilol

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Identification
Molecular formula
C24H26BrNO4
CAS number
72956-09-3
IUPAC name
2-bromo-N-[4-[1-[[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]-1-methyl-ethyl]-1-methyl-cyclohexyl]acetamide
State
State

At room temperature, carvedilol is in a solid state, typically as a crystalline powder.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
746.10
Boiling point (Kelvin)
1 019.30
General information
Molecular weight
406.49g/mol
Molar mass
406.4860g/mol
Density
1.2200g/cm3
Appearence

Carvedilol is usually found as a white to almost white crystalline powder.

Comment on solubility

Solubility of 2-bromo-N-[4-[1-[[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]-1-methyl-ethyl]-1-methyl-cyclohexyl]acetamide

The solubility of a compound can significantly influence its practical applications in various fields, including pharmaceuticals, agriculture, and material science. For the compound 2-bromo-N-[4-[1-[[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]-1-methyl-ethyl]-1-methyl-cyclohexyl]acetamide (C24H26BrNO4), understanding its solubility characteristics is essential.

While specific solubility data may vary, here are some general points to consider:

  • Polarity: The presence of various functional groups, such as the hydroxyl (-OH) and amino (-NH) groups, suggests that the compound may exhibit moderate solubility in polar solvents like water.
  • Hydrophobic Character: The bulky cyclohexyl and indole components could impart some hydrophobic characteristics, potentially limiting solubility in highly polar solvents.
  • Solvent Interaction: Solubility may be enhanced with co-solvents or in mixed solvent systems, particularly those containing both polar and non-polar components.
  • Temperature Effects: Like many compounds, solubility may increase with temperature, allowing for higher concentrations to be achieved in solution.

Overall, a thorough investigation of solubility is crucial for maximizing the compound's efficacy and utility. Comprehensive studies, including solubility curves and pH-dependent solubility tests, can provide valuable insights and help predict behavior in various environments.

Interesting facts

Interesting Facts About 2-Bromo-N-[4-[1-[[2-Hydroxy-3-(1H-Indol-4-yloxy)Propyl]Amino]-1-Methyl-Ethyl]-1-Methyl-Cyclohexyl]Acetamide

This compound stands out in the field of medicinal chemistry as it has unique structural characteristics that can lead to significant biological activity. Here are some engaging points to consider:

  • Complex Structure: The compound features multiple functional groups, including a bromo substituent and an acetamide moiety, which contribute to its chemical reactivity and potential therapeutic properties.
  • Indole Derivative: It incorporates an indole moiety, known for its prominence in pharmacology. Indoles are often found in various natural products and are key components in numerous pharmaceuticals due to their unique electronic properties.
  • Potential Biological Activity: Researchers are intrigued by compounds like this one for their potential roles in drug development, particularly in targeting neurotransmitter systems or as anti-cancer agents. The presence of the indolyl group often correlates with activities such as anti-inflammatory or anti-tumor effects.
  • Variety of Applications: Compounds with similar structural frameworks have been explored for uses ranging from antidepressants to anti-psychotic treatments. The specific arrangement of the cyclohexyl and hydropyl groups can influence the compound's binding affinity to biological targets.
  • In Silico Studies: The complexity of this compound makes it a worthy candidate for in silico studies and computational modeling, allowing scientists to predict its interactions with various biological molecules.

As a student or researcher in chemistry, one must appreciate the intricacies of such compounds, not only in their synthesis but also in understanding their potential applications in modern medicine and pharmaceuticals. These molecules exemplify the marvel of organic chemistry and the continuous pursuit of innovation in drug discovery.

Synonyms
Pindobind
106469-52-7
2-bromo-N-[4-[2-[[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]propan-2-yl]-1-methylcyclohexyl]acetamide
Pindobind 5-hydroxytryptamine(1A)
CHEMBL156628
N(1)-(Bromoacetyl)-N(8)-(3-(4-indolyloxy)-2-hydroxypropyl)-(Z)-1,8-diamino-4-menthane
2-Bromo-N-(4-(1-((2-hydroxy-3-(1H-indol-4-yloxy)propyl)amino)-1-methylethyl)-1-methylcyclohexyl)acetamide
Acetamide, 2-bromo-N-(4-(1-((2-hydroxy-3-(1H-indol-4-yloxy)propyl)amino)-1-methylethyl)-1-methylcyclohexyl)-
2-Bromo-N-[4-[1-[[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]-1-methylethyl]-1-methylcyclohexyl]acetamide
DTXSID80910012
BDBM50226718
PDSP1_001698
PDSP2_001681
L003444
Q7195029
Acetamide,2-bromo-N-[4-[1-[[2-hydroxy-3-(1H-indol-4-yloxy)propyl]amino]-1-methylethyl]-1-methylcyclohexyl]-