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2-Bromo-N-phenylbenzamide

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Identification
Molecular formula
C13H10BrNO
CAS number
38845-59-7
IUPAC name
2-bromo-N-phenyl-benzamide
State
State

At room temperature, 2-Bromo-N-phenylbenzamide is typically found in a solid state. It is stable and maintains its structural integrity under normal environmental conditions.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
290.13g/mol
Molar mass
290.1110g/mol
Density
1.4940g/cm3
Appearence

2-Bromo-N-phenylbenzamide typically presents as an off-white to pale yellow crystalline powder. Its appearance can be somewhat granular to the touch, with a slightly glossy sheen depending on the size of the crystals formed during its synthesis.

Comment on solubility

Solubility of 2-bromo-N-phenyl-benzamide (C13H10BrNO)

Understanding the solubility of 2-bromo-N-phenyl-benzamide is essential due to its implications in various chemical applications and processes. Here's a detailed look into its solubility characteristics:

  • Solvent Interaction: This compound is generally more soluble in organic solvents such as ethanol and DMSO, whereas its solubility in water is limited due to the presence of the aromatic rings which increase hydrophobic interactions.
  • Temperature Dependence: Like many organic compounds, the solubility of 2-bromo-N-phenyl-benzamide tends to increase with rising temperature due to enhanced molecular movement and reduced intermolecular forces.
  • Influence of Substituents: The presence of the bromo group can influence solubility; halogen groups often enhance the compound's polarity and ability to interact with solvents, albeit to a variable degree.

In summary, while the solubility of 2-bromo-N-phenyl-benzamide in water is low, it demonstrates favorable solubility in organic solvents under various conditions, facilitating its use in different chemical applications. The interplay between its chemical structure and environmental factors plays a crucial role in determining its solubility profile.

Interesting facts

Interesting Facts about 2-bromo-N-phenyl-benzamide

2-bromo-N-phenyl-benzamide is a fascinating compound that belongs to the class of amides, which play essential roles in various biological and chemical processes. Here are some intriguing highlights:

  • Pharmaceutical Relevance: This compound is often explored in medicinal chemistry for its potential pharmacological properties. The presence of the bromine atom can enhance the compound's biological activity, making it a candidate for further research in drug development.
  • Reaction Dynamics: The bromine substituent allows for various chemical reactions, including electrophilic substitution and nucleophilic substitution. This makes it versatile for synthetic applications in organic chemistry.
  • Structural Features: The configuration of the benzamide group is significant. The phenyl ring contributes to the compound’s stability and makes it an attractive subject for studies on molecular interactions and sterics.
  • Importance in Organic Synthesis: Due to its unique structure, 2-bromo-N-phenyl-benzamide can serve as a building block in the synthesis of more complex organic molecules, potentially leading to novel materials or compounds with unexpected properties.
  • Research Publications: There have been various studies highlighting the reactivity and applications of benzamide derivatives. Researchers often reference this compound when discussing the efficacy of brominated compounds in organic synthesis and pharmacology.

Thus, 2-bromo-N-phenyl-benzamide is not merely a chemical entity but a vital player in the fields of organic chemistry and drug discovery. Its unique characteristics make it a subject of continuous interest among chemists and biologists alike.

Synonyms
10282-57-2
Benzamide, 2-bromo-N-phenyl-
AI3-01074
DTXSID20145523
DTXCID6068014
2-BROMO-N-PHENYLBENZAMIDE
2-Bromo-N-phenyl-benzamide
Cambridge id 5306995
(2-bromophenyl)-N-benzamide
MLS002699909
SCHEMBL882734
CHEMBL1708490
CHEBI:92073
BHHGABOCAHPYMA-UHFFFAOYSA-N
AKOS000177441
SMR001563711
ST056368
AB00079774-01
SR-01000203790
SR-01000203790-1
BRD-K04156788-001-01-7
Q27163868
Z27782610