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Brompheniramine Maleate

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Identification
Molecular formula
C16H19BrClN
CAS number
86-22-6
IUPAC name
2-bromoethyl-[(4-chlorophenyl)methyl]-ethyl-ammonium;bromide
State
State

At room temperature, Brompheniramine maleate is typically found as a solid.

Melting point (Celsius)
116.00
Melting point (Kelvin)
389.15
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
433.25g/mol
Molar mass
433.2450g/mol
Density
1.4030g/cm3
Appearence

Brompheniramine maleate appears as a white to slightly yellow crystalline powder. It is known for its bitter taste and may emit a slight characteristic odor.

Comment on solubility

Solubility of 2-bromoethyl-[(4-chlorophenyl)methyl]-ethyl-ammonium bromide

The solubility of 2-bromoethyl-[(4-chlorophenyl)methyl]-ethyl-ammonium bromide is influenced by several factors, primarily its ionic nature and the presence of hydrophilic groups. As an ammonium salt, it tends to exhibit good solubility in polar solvents due to the following characteristics:

  • Polar interactions: The ammonium moiety can engage in hydrogen bonding with water, enhancing solubility.
  • Electrostatic forces: The bromide ion contributes to the ionic character, allowing the compound to dissolve well in polar environments.
  • Hydrophobic effects: While the chlorophenyl group exhibits hydrophobic properties, the overall structure remains more soluble than nonpolar compounds.

In general, one can expect the following:

  • High solubility in water and other polar solvents.
  • Limited solubility in nonpolar solvents.
  • Variations in solubility can occur depending on temperature: increased temperature often results in increased solubility.

In summary, while the presence of hydrophobic groups may suggest reduced solubility, the ionic nature of 2-bromoethyl-[(4-chlorophenyl)methyl]-ethyl-ammonium bromide promotes significant solubility in polar solvents, making it an intriguing compound in the realm of chemistry.

Interesting facts

Interesting Facts About 2-Bromoethyl-[(4-Chlorophenyl)methyl]-ethyl-ammonium Bromide

2-Bromoethyl-[(4-chlorophenyl)methyl]-ethyl-ammonium bromide is a fascinating compound with a variety of applications and unique properties. Here are some intriguing points about this compound:

  • Structure and Functionality: This compound features a quaternary ammonium structure, which is characterized by a nitrogen atom that is bonded to four organic groups. This can impart unique ionic and solubility properties, making this compound useful in a variety of chemical reactions.
  • Biological Applications: Quaternary ammonium compounds like this one often display antimicrobial properties. This makes them valuable candidates in pharmaceutical formulations or as disinfectants, owing to their ability to disrupt microbial cell membranes.
  • Versatile Reactivity: The presence of the bromoethyl group allows for potential nucleophilic substitution reactions, making this compound a key intermediate in organic synthesis. This reactivity opens doors to synthesizing more complex molecules!
  • Interactions with Biological Molecules: The chlorophenyl moiety may enhance the interaction of this compound with various biological targets, providing avenues for drug design and development. **The strategic positioning of the bromoethyl group can facilitate binding to certain receptors, enhancing the compound's efficacy.**
  • Potential Use in Surfactants: Due to their amphiphilic nature, compounds like 2-bromoethyl-[(4-chlorophenyl)methyl]-ethyl-ammonium bromide can be explored as surfactants. These could be beneficial in formulating emulsions, detergents, or other surface-active agents.

In conclusion, 2-bromoethyl-[(4-chlorophenyl)methyl]-ethyl-ammonium bromide is not just a chemical compound but a springboard for innovation in various fields such as medicinal chemistry, material science, and beyond.

Synonyms
19933-92-7
BENZYLAMINE, N-(2-BROMOETHYL)-p-CHLORO-N-ETHYL-, HYDROBROMIDE
JFA 9
N-(2-Bromoethyl)-p-chloro-N-ethylbenzylamine hydrobromide