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2-Phenylethylammonium bromide

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Identification
Molecular formula
C8H12BrN
CAS number
4360-63-8
IUPAC name
2-bromoethyl(phenyl)ammonium;bromide
State
State

At room temperature, 2-Phenylethylammonium bromide is typically found in a solid state. It is stable under normal conditions and does not easily decompose, but it should be stored in a dry environment to maintain its chemical integrity.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
248.10g/mol
Molar mass
248.0980g/mol
Density
1.0000g/cm3
Appearence

2-Phenylethylammonium bromide typically appears as a white to off-white crystalline solid. It may also be in a powder form and often has a characteristic odor associated with organic ammonium salts.

Comment on solubility

Solubility of 2-bromoethyl(phenyl)ammonium bromide

2-bromoethyl(phenyl)ammonium bromide exhibits moderate solubility in polar solvents, particularly in water and alcohols. This solubility behavior can be attributed to the following factors:

  • Polar Nature: The presence of the ammonium group contributes to the compound's polarity, enhancing its ability to interact with polar solvents.
  • Ionic Characteristics: The bromide ion (Br-) enhances solubility as it can readily dissociate in aqueous solution, facilitating ion-dipole interactions.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules increases solvation and contributes to a higher solubility profile.

However, the solubility may be limited in non-polar solvents due to:

  • Hydrophobic Phenyl Group: The presence of the phenyl group can hinder solubility in non-polar environments, as it is more hydrophobic in nature.
  • Steric Hindrance: The bulky structure of the compound can affect its ability to solvate effectively in certain conditions.

In summary, while 2-bromoethyl(phenyl)ammonium bromide is soluble in polar solvents, it tends to be less soluble in non-polar media. This knowledge can be vital for applications requiring specific solvent systems.

Interesting facts

Interesting Facts about 2-Bromoethyl(phenyl)ammonium Bromide

2-Bromoethyl(phenyl)ammonium bromide is a fascinating compound with various implications in the fields of organic chemistry and medicinal science. This quaternary ammonium compound serves as a valuable intermediate in numerous synthetic reactions.

Key Characteristics:

  • Electrophilic Nature: The 2-bromoethyl group attached to the ammonium cation provides an electrophilic center, making it a useful building block in organic synthesis.
  • Biological Activity: Compounds of this type often exhibit pharmacological properties, showing potential as antimicrobial agents, appreciable in drug synthesis.
  • Pioneering Research: Interest in 2-bromoethyl(phenyl)ammonium bromide has led to explorations into its role in synthesizing compounds that can target specific pathways in diseases.

One of the exciting aspects of this compound lies in its potential applications, particularly in:

  • ✔ Targeted drug delivery systems
  • ✔ Organic synthesis methodologies
  • ✔ Development of antimicrobial agents

Chemical Interactions:

On the molecular level, 2-bromoethyl(phenyl)ammonium bromide can participate in a variety of chemical reactions, which include:

  1. Reacting with nucleophiles to form new compounds
  2. Acting as an alkylating agent in various synthetic pathways
  3. Participating in electrophilic substitutions due to its bromoethyl moiety

In conclusion, 2-bromoethyl(phenyl)ammonium bromide is not just a mere compound; it represents the complexity and versatility found within the realm of organic chemistry. As researchers continue to unveil its potential, we can expect to see its influence expand across numerous scientific disciplines.

Synonyms
N-Phenyl-beta-bromoethylamine hydrobromide
EINECS 213-738-5
NSC 25318
N-(2-Bromoethyl)benzenamine hydrobromide
Benzenamine, N-(2-bromoethyl)-, hydrobromide
ANILINE, N-(2-BROMOETHYL)-, HYDROBROMIDE
2-Bromoethyl-phenylazanium bromide
DB-251399
NS00080004