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Curcumin

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Identification
Molecular formula
C21H20O6
CAS number
458-37-7
IUPAC name
2-butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one
State
State

Curcumin is a solid at room temperature, appearing as bright yellow, crystalline powder. Due to its poor solubility in water, it retains its powder form without dissolving readily.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.00
Boiling point (Celsius)
580.00
Boiling point (Kelvin)
853.00
General information
Molecular weight
368.38g/mol
Molar mass
368.3840g/mol
Density
1.3000g/cm3
Appearence

Curcumin is a bright yellow crystalline compound. It is commonly encountered as a yellow-orange powder, which can be used as a colorant in foods and cosmetics. It has poor solubility in water, which contributes to its vivid color intensity when used in applications.

Comment on solubility

Solubility of 2-butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one

When examining the solubility of the complex compound 2-butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one, several factors must be considered:

  • Polarity: The presence of multiple hydroxyl groups in the structure significantly enhances its affinity for water, indicating potential solubility in polar solvents.
  • Hydrophobic Regions: However, the hydrophobic characteristics of the butanoyl moieties may limit solubility in pure water, making it more soluble in organic solvents.
  • Temperature Influence: Elevated temperatures often increase the solubility of organic compounds, which could be beneficial for dissolving this specific compound in various media.
  • pH Sensitivity: The solubility can also vary with pH, given the compound's multiple hydroxyl groups that can ionize under different conditions.

In essence, while the structure suggests a blend of hydrophilic and hydrophobic segments, soliciting specific solvent systems and temperature conditions will help determine the exact solubility behavior of this compound. Comprehensive empirical analysis remains the key to understanding its solubility profile.

Interesting facts

Exploring 2-butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methyl-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one

This fascinating compound, with its intricate name, is a part of the broad category of chemical substances known as flavonoids. Flavonoids are well-known for their various health benefits and biological activities. Let's delve into some intriguing facts about this compound:

  • Biological Significance: Compounds like this one often exhibit significant antioxidant properties, which play a crucial role in fighting free radicals in the body.
  • Natural Occurrence: Compounds with similar structures are commonly found in a variety of fruits, vegetables, and herbs, contributing to their color and flavor.
  • Potential Therapeutic Applications: Researchers are investigating flavonoids for their potential in drug discovery and as natural remedies, particularly in combating inflammation and chronic diseases.
  • Synthetic Challenges: The complex structure of this compound reflects the challenges faced in its synthesis, requiring advanced techniques in organic chemistry.

Quote by a Prominent Chemist: “The beauty of chemistry lies in the intricate dance of molecules – each with a story to tell, and each with its own unique role in the ecosystem of life.”

Understanding such compounds broadens our knowledge not only of chemistry but also of the natural world. It highlights how chemical structures can influence biological functions and the importance of ongoing research in this field. This is an exciting area for both students and seasoned chemists alike!

Synonyms
p-Aspidin
p-Aspidin BB
Paraaspidin
989-54-8
2-butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxy-5-methylphenyl)methyl]-3,5-dihydroxy-6,6-dimethylcyclohexa-2,4-dien-1-one
Butyrophenone, 3'-((5-butyryl-2,4-dihydroxy-3,3-dimethyl-6-oxo-1,4-cyclohexadien-1-yl)methyl)-2',6'-dihydroxy-4'-methoxy-5'-methyl-
2,5-Cyclohexadien-1-one, 2-[[2,4-dihydroxy-6-methoxy-5-methyl-3-(1-oxobutyl)phenyl]methyl]-3,5-dihydroxy-4,4-dimethyl-6-(1-oxobutyl)-
BRN 2230587
Para-aspidin
para-Aspidin BB
Butyrophenone, 3'-[(5-butyryl-2,4-dihydroxy-3,3-dimethyl-6-oxo-1,4-cyclohexadien-1-yl)methyl]-2',6'-dihydroxy-4'-methoxy-5'-methyl-
PEU4NN4UZ8
3-08-00-04399 (Beilstein Handbook Reference)
DTXSID60912998
CMKHZPXDAXVNES-UHFFFAOYSA-N
2-[[2,4-Dihydroxy-6-methoxy-5-methyl-3-(1-oxobutyl)phenyl]methyl]-3,5-dihydroxy-4,4-dimethyl-6-(1-oxobutyl)-2,5-cyclohexadien-1-one
2-Butyryl-6-(3-butyryl-2,4-dihydroxy-6-methoxy-5-methylbenzyl)-3,5-dihydroxy-4,4-dimethyl-2,5-cyclohexadien-1-one #