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Curcumin

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Identification
Molecular formula
C21H20O6
CAS number
458-37-7
IUPAC name
2-butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxy-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one
State
State

At room temperature, curcumin is a solid. It is typically seen as a powder or crystalline solid and remains in this state under standard conditions of temperature and pressure.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
469.85
Boiling point (Kelvin)
742.85
General information
Molecular weight
368.39g/mol
Molar mass
368.3850g/mol
Density
1.3630g/cm3
Appearence

Curcumin is a bright yellow crystalline solid. It is often available in powder form, exhibiting a vibrant orange-yellow color. Curcumin is known for its distinct and vivid hue, which is why it is commonly used as a coloring agent in foods and cosmetics.

Comment on solubility

Solubility of 2-butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxy-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one

The solubility of 2-butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxy-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one can be influenced by various factors, including its intricate molecular structure and functional groups. Understanding its solubility characteristics allows for a deeper insight into its potential applications and behavior in different environments.

General Insights on Solubility

This compound, which is rich in hydroxyl groups, can exhibit:

  • Hydrophilicity: The presence of multiple hydroxyl (-OH) groups typically enhances water solubility due to hydrogen bonding.
  • Hydrophobic Regions: The butanoyl and methyl groups may render parts of the molecule hydrophobic, which might reduce overall solubility in polar solvents.

Consequently, the solubility may vary significantly based on:

  • Temperature: Higher temperatures often increase solubility for many organic compounds.
  • Solvent Type: The choice of solvent is crucial; this compound may be more soluble in organic solvents than in water.
  • pH Levels: Changes in pH can affect the ionization of functional groups, thereby influencing solubility.

In summary, while the solubility of 2-butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxy-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one is likely enhanced by its multiple hydroxyl groups, the presence of hydrophobic elements adds complexity. Exploring these nuances provides valuable insights into its behavior in various chemical contexts.

Interesting facts

Interesting Facts about 2-butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxy-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one

This compound is a fascinating example of organic chemistry due to its complex structure and potential applications. Here are some intriguing aspects to consider:

  • Structural Composition: The compound features a cyclohexadienone framework, showcasing significant structural diversity with multiple functional groups including ketones, hydroxyls, and methoxy groups. This diversity often leads to unique reactivity and interactions.
  • Biological Relevance: Many compounds with similar structures have been studied for their pharmacological properties. They may exhibit activities such as antioxidant, anti-inflammatory, or even anticancer effects, which makes them of interest in medicinal chemistry.
  • Synthesis Challenges: The synthesis of complex organic molecules like this one typically involves challenging steps that require careful control of reaction conditions. Techniques such as selective functionalization and stereochemistry control are often crucial in ensuring successful syntheses.
  • Potential Applications: Compounds of this type may find use in various applications ranging from pharmaceuticals to agrochemicals, as their unique structures can lead to desirable biological activities.
  • Research Opportunities: The ongoing research into compounds similar to this one presents opportunities for new discoveries. Investigating their mechanisms of action could unlock a wider understanding of their potential therapeutic roles.

As a final note, the study of such intricate compounds highlights the beauty and complexity of organic molecules. Each molecule tells a different story, often leading to new scientific inquiries and advancements in various fields of chemistry and biochemistry.

Synonyms
Desaspidin
Desaspidin BB
Rosapin
114-43-2
Desaspidin [INN]
Desaspidina
Desaspidine
KV3495SGKS
60842-45-7
Desaspidin (INN)
2-butanoyl-4-[(3-butanoyl-2,4-dihydroxy-6-methoxyphenyl)methyl]-3,5-dihydroxy-6,6-dimethylcyclohexa-2,4-dien-1-one
3'-((5-Butyryl-2,4-dihydroxy-3,3-dimethyl-6-oxo-1,4-cyclohexadien-1-yl)methyl)-2',6'-dihydroxy-4'-methoxybutyrophenone
Butyrophenone, 3'-((5-butyryl-2,4-dihydroxy-3,3-dimethyl-6-oxo-1,4-cyclohexadien-1-yl)methyl)-2',6'-dihydroxy-4'-methoxy-
Desaspidinum
Desapidin
Desaspidine [INN-French]
Desaspidinum [INN-Latin]
Desaspidina [INN-Spanish]
2,5-Cyclohexadien-1-one, 2-((2,4-dihydroxy-6-methoxy-3-(1-oxobutyl)phenyl)methyl)-3,5-dihydroxy-4,4-dimethyl-6-(1-oxobutyl)-
EINECS 204-048-5
UNII-KV3495SGKS
BRN 2068482
Deaspidin
2,5-Cyclohexadien-1-one, 2-[[2,4-dihydroxy-6-methoxy-3-(1-oxobutyl)phenyl]methyl]-3,5-dihydroxy-4,4-dimethyl-6-(1-oxobutyl)-
3'-[(5-Butyryl-2,4-dihydroxy-3,3-dimethyl-6-oxo-1,4-cyclohexadien-1-yl)methyl]-2',6'-dihydroxy-4'-methoxybutyrophenone
DESASPIDIN BB [MI]
DESASPIDIN [WHO-DD]
4-08-00-03747 (Beilstein Handbook Reference)
SCHEMBL2732746
CHEMBL2105606
DTXSID6074461
DTXSID00976317
CHEBI:135960
GAHOBHHMYUYJDT-UHFFFAOYSA-N
XDIZFCKCCMUFFG-UHFFFAOYSA-N
DB13567
NS00023712
D07365
Q904668
2-Butyryl-6-(3-butyryl-2,4-dihydroxy-6-methoxybenzyl)-3,5-dihydroxy-4,4-dimethyl-2,5-cyclohexadien-1-one #