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Curcumin

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Identification
Molecular formula
C21H20O6
CAS number
458-37-7
IUPAC name
2-butanoyl-4-[(3-butanoyl-2,4,6-trihydroxy-5-methyl-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one
State
State

Curcumin is typically in a solid state at room temperature. It is usually found as a crystalline powder before being dissolved for laboratory or industrial use.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.00
Boiling point (Celsius)
650.00
Boiling point (Kelvin)
923.00
General information
Molecular weight
368.39g/mol
Molar mass
368.3850g/mol
Density
1.3000g/cm3
Appearence

Curcumin is a bright yellow or orange-yellow crystalline powder. It is commonly found in turmeric, which contributes to the spice's vibrant color. The crystalline form may appear under a microscope as uniformly shaped particles.

Comment on solubility

Solubility of 2-butanoyl-4-[(3-butanoyl-2,4,6-trihydroxy-5-methyl-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one

The solubility of 2-butanoyl-4-[(3-butanoyl-2,4,6-trihydroxy-5-methyl-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one can be characterized by several key points:

  • Polarity: This compound has multiple hydroxyl (-OH) groups, which typically enhance solubility in polar solvents such as water.
  • Solvent Interaction: It is likely to display better solubility in organic solvents due to its larger hydrophobic carbon chains and aromatic structure.
  • Temperature Influence: Increasing the temperature usually improves solubility for many compounds, and this compound might exhibit similar behavior.
  • Concentration Factors: Solubility can also change based on concentration; thus, it may reach saturation in a given solvent at a specific concentration.

While multiple factors influence the solubility of this complex compound, the predominant characteristics highlight the effect of both its hydrophilic and hydrophobic components. As a result, it's important to consider specific solvents and their properties for optimal dissolution. Understanding these interactions will help predict its behavior in various chemical environments, making solubility a critical factor in practical applications.

Interesting facts

Interesting Facts about 2-butanoyl-4-[(3-butanoyl-2,4,6-trihydroxy-5-methyl-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one

This compound, known for its intricate structure and unique characteristics, belongs to a fascinating class of organic compounds that are often involved in various biological and chemical processes. Here are some interesting facts:

  • Complex Structure: The chemical structure includes multiple functional groups, such as hydroxyl and carbonyl moieties, which significantly influence its reactivity and biological interactions.
  • Potential Biological Activity: Compounds of this nature are often investigated for their potential pharmacological properties, making them subjects of interest in medicinal chemistry.
  • Natural Sources: Many structurally similar compounds are derived from natural products, which are critical in the development of new drugs and therapies.
  • Synthetic Routes: The synthesis of such complicated structures can be a remarkable demonstration of organic synthesis techniques, including multi-step reactions and protecting group strategies.

As noted by renowned chemist John M. C. Hutchison, "Complex molecules tell complex stories." This compound's intricate design not only reflects the ingenuity of organic synthesis but also opens avenues for further research in fields such as:

  • Pharmacology
  • Material Science
  • Environmental Chemistry

With further investigation and exploration, understanding compounds like 2-butanoyl-4-[(3-butanoyl-2,4,6-trihydroxy-5-methyl-phenyl)methyl]-3,5-dihydroxy-6,6-dimethyl-cyclohexa-2,4-dien-1-one could lead to groundbreaking applications in scientific research and development.

Synonyms
Flavaspidic acid
Toxifren
114-42-1
Flavaspidic acid BB
Glavaspidic acid
Flavaspidsaeure
2-butanoyl-4-[(3-butanoyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-3,5-dihydroxy-6,6-dimethylcyclohexa-2,4-dien-1-one
NSC 115497
NSC-115497
7HFR949XW9
NSC115497
Butyrophenone, 3'-((5-butyryl-2,4-dihydroxy-3,3-dimethyl-6-oxo-1,4-cyclohexadien-1-yl)methyl)-2',4',6'-trihydroxy-5'-methyl-
Flavaspidsaeure [German]
2,5-Cyclohexadien-1-one, 3,5-dihydroxy-4,4-dimethyl-2-(1-oxobutyl)-6-((2,4,6-trihydroxy-3-methyl-5-(1-oxobutyl)phenyl)methyl)-
BRN 2068481
UNII-7HFR949XW9
2,5-Cyclohexadien-1-one, 3,5-dihydroxy-4,4-dimethyl-2-(1-oxobutyl)-6-[[2,4,6-trihydroxy-3-methyl-5-(1-oxobutyl)phenyl]methyl]-
4-08-00-03748 (Beilstein Handbook Reference)
FLAVASPIDIC ACID [MI]
CHEMBL291819
SCHEMBL1785484
DTXSID90878659
3'-((5-Butyryl-2,4-dihydroxy-3,3-dimethyl-6-oxo-1,4-cyclohexadien-1-yl)methyl)-5'-methylphloro butyrophenone
NCI60_000345
FLAVASPIDIC ACID .BETA.-FORM [MI]
DS-003662
FLAVASPIDIC ACID .ALPHA.-FORM [MI]
NS00094857
Q5458045
WLN: L6V DHJ BV3 CQ D1 D1 EQ F1R BQ DQ FQ C1 EV3
2, 3,5-dihydroxy-4,4-dimethyl-2-(1-oxobutyl)-6-[[2,4,6-trihydroxy-3-methyl-5-(1-oxobutyl)phenyl]methyl]-
2,5-Cyclohexadien-1-one,3,5-dihydroxy-4,4-dimethyl-2-(1-oxobutyl)-6-[[2,4,6-trihydroxy-3-methyl-5-(1-oxobutyl)phenyl]methyl]-
2-butanoyl-6-[(3-butanoyl-2,4,6-trihydroxy-5-methyl-phenyl)methyl]-3,5-dihydroxy-4,4-dimethyl-cyclohexa-2,5-dien-1-one
3,5-DIHYDROXY-4,4-DIMETHYL-2-(1-OXOBUTYL)-6-((2,4,6-TRIHYDROXY-3-METHYL-5-(1-OXOBUTYL)PHENYL)METHYL)-2,5-CYCLOHEXADIEN-1-ONE
Butyrophenone,4-dihydroxy-3,3-dimethyl-6-oxo-1,4-cyclohexadien-1-yl)methyl]-2',4',6'-trihydroxy-5'-methyl-
PHLOROBUTYROPHENONE, 3'-((5-BUTYRYL-2,4-DIHYDROXY-3,3-DIMETHYL-6-OXO-1,4-CYCLOHEXADIEN-1-YL)METHYL)-5'-METHYL-