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Bufenol

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Identification
Molecular formula
C12H16FNO
CAS number
33326-25-9
IUPAC name
2-(butylamino)-1-(3-fluorophenyl)ethanol
State
State

At room temperature, Bufenol is typically in a liquid state. It remains stable as a clear liquid under normal conditions but may solidify upon cooling below its melting point.

Melting point (Celsius)
-10.00
Melting point (Kelvin)
263.15
Boiling point (Celsius)
332.90
Boiling point (Kelvin)
606.05
General information
Molecular weight
211.26g/mol
Molar mass
211.2800g/mol
Density
1.1149g/cm3
Appearence

Bufenol typically appears as a colorless or pale yellow liquid. The liquid is usually transparent with a slightly viscous consistency. It may also emit a mild aromatic odor due to its phenyl group.

Comment on solubility

Solubility of 2-(butylamino)-1-(3-fluorophenyl)ethanol

The solubility of 2-(butylamino)-1-(3-fluorophenyl)ethanol can be an intriguing subject due to its molecular structure and functional groups. Here are some key points to consider:

  • Polarity: The presence of both a butylamino group and a fluorophenyl group contributes to the overall polarity of the compound. This polarity can significantly influence its solubility in different solvents.
  • Solvent Compatibility: This compound is likely to be more soluble in polar protic solvents, such as:
    • Water
    • Alcohols
  • In contrast, solubility in non-polar solvents (e.g., hydrocarbons) is expected to be lower due to the strong intermolecular interactions present in polar environments.
  • Hydrogen Bonding: The presence of -NH groups in the butylamino segment could engage in hydrogen bonding, further enhancing solubility in aqueous solutions.
  • Temperature Impact: As with many organic compounds, solubility can increase with temperature, making it essential to consider the context in which the compound is used.

In summary, the solubility characteristics of 2-(butylamino)-1-(3-fluorophenyl)ethanol suggest a favorable interaction with polar solvents, making it a versatile compound in various chemical applications. Understanding its solubility is vital for predicting behavior in biological systems or chemical reactions.

Interesting facts

Interesting Facts about 2-(butylamino)-1-(3-fluorophenyl)ethanol

2-(butylamino)-1-(3-fluorophenyl)ethanol is a fascinating compound that belongs to the class of amines. This chemical exhibits unique properties and potential applications that pique the interest of chemists and researchers alike.

Key Characteristics

  • Biological Activity: The compound has garnered attention due to its potential role in pharmacology, particularly as a therapeutic agent. Its ability to interact with biological systems opens avenues for medicinal chemistry.
  • Fluorinated Substituents: The presence of a fluorine atom not only enhances the biological activity but also provides increased stability in various chemical environments. Fluorine is known for modifying the physicochemical properties of organic compounds.
  • Amine Functionality: The butylamino group is crucial for its interaction with biological targets, which makes it valuable in drug design. Amines are often pivotal in forming hydrogen bonds, impacting solubility and bioavailability.

Significance in Research

This compound is a subject of interest in various fields including:

  • Pharmaceutical Development: Researchers are exploring its derivatives for potential therapeutic benefits.
  • Organic Synthesis: Its structure provides a basis for exploring new synthetic methods and reactions in organic chemistry.

Quote to Reflect

As a reminder of the compound's potential, a famous saying in chemistry goes: "The discovery of a new reaction is like finding a new island." This reflects the journey of ongoing exploration in the realm of chemical compounds.


Understanding compounds like 2-(butylamino)-1-(3-fluorophenyl)ethanol not only broadens our knowledge of chemical interactions but also propels innovation in scientific research and industrial applications.

Synonyms
63991-37-7
alpha-[(Butylamino)methyl]-3-fluorobenzyl alcohol
2-Butylamino-1-(3-fluorophenyl)ethanol
Ethanol, 2-butylamino-1-(3-fluorophenyl)-
alpha-(Butylaminomethyl)-3-fluorobenzyl alcohol
BENZYL ALCOHOL, alpha-(BUTYLAMINOMETHYL)-3-FLUORO-
SCHEMBL10875706
DTXSID00981820
DB-321876
2-(Butylamino)-1-(3-fluorophenyl)ethan-1-ol
alpha-[(butylamino)methyl ]-3-fluorobenzyl alcohol