Skip to main content

Bupropion

ADVERTISEMENT
Identification
Molecular formula
C13H18ClNO
CAS number
31677-93-7
IUPAC name
2-(butylamino)-N-(2-chloro-6-methyl-phenyl)acetamide
State
State

At room temperature, bupropion is typically found in a solid state, specifically as a crystalline powder when in its hydrochloride form.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
389.30
Boiling point (Kelvin)
662.45
General information
Molecular weight
239.74g/mol
Molar mass
239.7380g/mol
Density
1.2000g/cm3
Appearence

Bupropion hydrochloride is a white to off-white, crystalline powder. It is highly soluble in water and methanol and only moderately soluble in ethanol.

Comment on solubility

Solubility of 2-(butylamino)-N-(2-chloro-6-methyl-phenyl)acetamide

The solubility of 2-(butylamino)-N-(2-chloro-6-methyl-phenyl)acetamide can be influenced by various factors, making it a compound of interest for solubility studies. Here are some key points to consider:

  • Polarity: The presence of both an amine group and a chloro-substituent contributes to its overall polarity, which affects its dissolution in different solvents.
  • Solvent Type: Generally, this compound is expected to be more soluble in polar solvents like water or methanol compared to non-polar solvents, due to its polar functional groups.
  • Temperature Dependency: Like many organic compounds, the solubility of 2-(butylamino)-N-(2-chloro-6-methyl-phenyl)acetamide may increase with temperature, aiding in its dissolve rate in solvents.
  • Concentration Effects: At higher concentrations, solubility can be affected by intermolecular interactions, leading to potential saturation and reduced solubility.

In summary, determining the solubility characteristics requires careful examination of its chemical structure, the nature of the solvent, and external conditions such as temperature. This emphasizes the significance of understanding solubility in enhancing the applicability and effectiveness of the compound in various chemical processes.

Interesting facts

Interesting Facts about 2-(butylamino)-N-(2-chloro-6-methyl-phenyl)acetamide

2-(butylamino)-N-(2-chloro-6-methyl-phenyl)acetamide is a compound that showcases fascinating aspects in the field of medicinal chemistry. Its structure indicates that it contains both an amine and a chloro group, which can significantly influence its biological activity.

Biological Significance

This compound is primarily studied for its potential pharmaceutical applications, particularly in the development of therapies for various medical conditions. Here are some key points:

  • Targeted Treatment: Molecules like this one can be optimized to act on specific biological targets, offering the potential for more effective treatments with reduced side effects.
  • Structure-Activity Relationship (SAR): The unique arrangement of butylamino and chloro groups allows researchers to investigate how structural changes can affect the compound's interaction with biological systems.
  • Pharmacokinetics: As a compound designed for medicinal purposes, understanding the absorption, distribution, metabolism, and excretion (ADME) properties can lead to improved drug formulations.

Applications in Research

In the laboratory, 2-(butylamino)-N-(2-chloro-6-methyl-phenyl)acetamide serves as an important tool for research:

  • Drug Development: It can be utilized as a lead compound from which new analogs can be synthesized, paving the way for innovative medications.
  • Chemistry Education: This compound is introduced in academic settings to teach students about organic synthesis and the importance of functional groups in molecular interactions.
  • Testing for Efficacy: Researchers often use a variety of assays to evaluate its effects on cell lines, thus providing insights into its mechanisms of action.

As a compound, 2-(butylamino)-N-(2-chloro-6-methyl-phenyl)acetamide epitomizes the complexity and potential of chemical compounds in developing treatments that could impact human health profoundly. Its continued study exemplifies the synergy between chemistry and biology!

Synonyms
Butanilicaine
3785-21-5
Butacetoluide
Butanilicaina
Butanilicainum
2-(Butylamino)-6'-chloro-o-acetoluidide
2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide
2-Butylamino-6'-chloro-o-acetotoluidide
Butanilicaine [INN:BAN]
Butanilicainum [INN-Latin]
UNII-7X3WV51F4N
Butanilicaina [INN-Spanish]
7X3WV51F4N
Butanilicaine (INN)
CHEBI:55518
BUTANILICAINE [MI]
BUTANILICAINE [INN]
BUTANILICAINE [WHO-DD]
Butanilicaine hydrochloride
DTXSID90191279
Hostacain
N(2)-butyl-N-(2-chloro-6-methylphenyl)glycinamide
Butanilicaine HCl
2-(Butylamino)-6'-chloro-o-acetotoluidide
Butanilicainum (INN-Latin)
Butanilicaina (INN-Spanish)
UNII-025O9D1EB7
025O9D1EB7
EINECS 227-893-1
BUTANILICAINE HYDROCHLORIDE [MI]
BUTANILICAINE HYDROCHLORIDE (MART.)
BUTANILICAINE HYDROCHLORIDE [MART.]
C 3050
2-(Butylamino)-6'-chloro-o-acetotoluidide hydrochloride
2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide hydrochloride
Acetamide, 2-(butylamino)-N-(2-chloro-6-methylphenyl)-, monohydrochloride
o-ACETOTOLUIDIDE, 2-(BUTYLAMINO)-6'-CHLORO-, MONOHYDROCHLORIDE
6027-28-7
DTXCID50113770
N01BB05
Acetamide, 2-(butylamino)-N-(2-chloro-6-methylphenyl)-, monohydrochloride (9CI)
227-893-1
vwyqkfllgrbicz-uhfffaoysa-n
Acetamide, 2-(butylamino)-N-(2-chloro-6-methylphenyl)-
starbld0009539
SCHEMBL25983
CHEMBL2104238
DB13328
FB148400
NS00006869
D07284
Q5002356
2-(Butylamino)-N-(2-chloro-6-methylphenyl)acetamide #