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Irbesartan

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Identification
Molecular formula
C25H28N6O
CAS number
138402-11-6
IUPAC name
2-(carboxymethoxy)-5-[2-[[2-(3-carboxypropanoylamino)-3-phenyl-propanoyl]amino]-3-oxo-3-(pentylamino)propyl]benzoic acid
State
State

Irbesartan is commonly found in its solid form at room temperature, making it easy to handle and distribute in pharmaceutical preparations. It is generally used in a solid dosage form such as tablets.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.20
Boiling point (Celsius)
877.10
Boiling point (Kelvin)
1 150.30
General information
Molecular weight
428.53g/mol
Molar mass
428.4530g/mol
Density
1.4692g/cm3
Appearence

Irbesartan is a white to off-white crystalline powder. As a crystalline substance, it has a defined lattice structure and distinct edges and faces, a typical characteristic of many solid compounds.

Comment on solubility

Solubility of 2-(carboxymethoxy)-5-[2-[[2-(3-carboxypropanoylamino)-3-phenyl-propanoyl]amino]-3-oxo-3-(pentylamino)propyl]benzoic acid

The solubility of this compound, with the molecular formula C25H28N6O, can be influenced by several factors primarily related to its structure and functional groups. Let's explore some key aspects of its solubility:

  • The presence of multiple functional groups, such as carboxylic acids, suggests that the compound can exhibit strong hydrogen bonding abilities, which typically enhances solubility in polar solvents.
  • Due to its larger hydrophobic regions (like the pentylamine moiety), solubility may decrease in highly polar solvents, indicating a preference for less polar or apolar solvents.
  • The size and complexity of the molecule may lead to steric hindrance, affecting its ability to interact with solvents.
  • As a result of these combined attributes, one might expect varied solubility profiles depending on solvent characteristics, perhaps exhibiting higher solubility in aqueous environments due to the carboxylic acid groups.

In conclusion, while definitive solubility values may require experimental validation, we can anticipate that this compound will be more soluble in polar solvents relative to non-polar ones, showcasing the intricate balance between hydrophobic and hydrophilic interactions.

Interesting facts

Interesting Facts about 2-(Carboxymethoxy)-5-[2-[[2-(3-carboxypropanoylamino)-3-phenyl-propanoyl]amino]-3-oxo-3-(pentylamino)propyl]benzoic Acid

This compound, with its complex structure, represents a fascinating intersection of medicinal chemistry and pharmaceutical research. Here are some intriguing insights into this multifaceted molecule:

  • Role in Drug Design: The presence of multiple functional groups in its structure indicates potential for interacting with various biological targets, making it a candidate for drug development.
  • Amino Acid Derivative: The incorporation of amino acid motifs suggests that this compound could mimic natural substrates, allowing it to engage in specific biochemical interactions.
  • Anti-Cancer Potential: Compounds with similar structural features have shown promise in anti-cancer therapy, often acting as inhibitors of key enzymes involved in tumor growth and proliferation.
  • Biological Activity: The diverse range of substituents, including carboxylic acid groups, can influence the molecule’s solubility and bioavailability, critical factors in determining its pharmacological effects.
  • Structural Complexity: The intricate arrangement of carbon, nitrogen, and oxygen atoms exemplifies the creativity possible in organic chemistry. Its diverse functional groups open avenues for further synthetic modifications.
  • Analytical Techniques: Understanding its molecular behavior often utilizes advanced techniques such as NMR spectroscopy and mass spectrometry, illustrating the compound’s unique characteristics.

In the words of noted chemist Linus Pauling, “The properties of a substance depend on its chemical structure.” This holds true for 2-(carboxymethoxy)-5-[2-[[2-(3-carboxypropanoylamino)-3-phenyl-propanoyl]amino]-3-oxo-3-(pentylamino)propyl]benzoic acid, showcasing how structural elements dictate its potential applications in medicine.

As this compound continues to be studied, it may lead to breakthroughs in therapeutic strategies, underlining the importance of chemical research in advancing human health.

Synonyms
SCHEMBL4317427
PD040371