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Pirfenidone

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Identification
Molecular formula
C12H11NO3
CAS number
53179-13-8
IUPAC name
2-(carboxymethyl)-2,4-dihydroxy-4-oxo-butanoate;dimethyl-[2-[3-(2-pyridyl)isoxazol-5-yl]ethyl]ammonium
State
State

At room temperature, pirfenidone is in a solid state, typically found as a crystalline powder.

Melting point (Celsius)
36.70
Melting point (Kelvin)
309.90
Boiling point (Celsius)
457.30
Boiling point (Kelvin)
730.40
General information
Molecular weight
185.22g/mol
Molar mass
185.2190g/mol
Density
1.1850g/cm3
Appearence

Pirfenidone appears as a white to slightly yellow crystalline powder. It is slightly soluble in water and has a relatively high solubility in organic solvents such as ethanol and dimethyl sulfoxide (DMSO).

Comment on solubility

Solubility of 2-(carboxymethyl)-2,4-dihydroxy-4-oxo-butanoate;dimethyl-[2-[3-(2-pyridyl)isoxazol-5-yl]ethyl]ammonium

The solubility of the compound 2-(carboxymethyl)-2,4-dihydroxy-4-oxo-butanoate;dimethyl-[2-[3-(2-pyridyl)isoxazol-5-yl]ethyl]ammonium is influenced by its complex structure, which contains both polar and non-polar functional groups. Here are some key points regarding its solubility:

  • Polar Nature: The presence of carboxymethyl and hydroxy groups suggests that this compound may exhibit a degree of polarity, which can enhance its solubility in polar solvents such as water.
  • Ammonium Group: The dimethylammonium moiety contributes to the solubility in aqueous environments due to its ability to interact through hydrogen bonding and ionic interactions.
  • Hydrophobic Interactions: The isoxazole ring and pyridine component introduce some hydrophobic characteristics, which may lead to decreased solubility in highly polar environments.
  • Overall Solubility: While the compound may dissolve in water due to its polar groups, the presence of hydrophobic components may limit its solubility compared to fully polar compounds.

In conclusion, the solubility of this chemical compound can be described as variable; the interplay of its polar and non-polar functional groups will dictate how it behaves in different solvent environments. It is essential to consider these factors when predicting its solubility in practical applications.

Interesting facts

Interesting Facts about 2-(Carboxymethyl)-2,4-dihydroxy-4-oxo-butanoate; Dimethyl-[2-[3-(2-pyridyl)isoxazol-5-yl]ethyl]ammonium

This chemical compound, characterized by its complex structure, showcases an intricate blend of functional groups that contribute to its unique chemical properties. Here are some fascinating aspects:

  • Biological Significance: The compound is often studied for its potential applications in biological systems, such as its role in metabolic pathways or as a pharmacophore.
  • Isoxazole Ring: The presence of the isoxazole moiety indicates that this compound may possess particular biological activities, such as antimicrobial or anti-inflammatory effects.
  • Dimethylammonium Group: The incorporation of a dimethylammonium group enhances solubility in polar environments, which can lead to interesting interactions in biochemical settings.
  • Potential Applications: Researchers are exploring the implications of this compound in drug development, particularly for targeting specific enzymes or receptors in biological systems.

Overall, 2-(carboxymethyl)-2,4-dihydroxy-4-oxo-butanoate; dimethyl-[2-[3-(2-pyridyl)isoxazol-5-yl]ethyl]ammonium illustrates the remarkable creativity of nature’s chemistry. As described by renowned chemist Robert H. Grubbs, "The joy of discovery is one of the greatest gifts of life." This compound may very well be a stepping stone toward exciting new advancements in pharmacology!

Synonyms
14732-53-7
ISOXAZOLE, 5-(2-(DIMETHYLAMINO)ETHYL)-3-(2-PYRIDYL)-, CITRATE
3-(2-Pyridyl)-5-(2-(dimethylamino)ethyl)-isoxazole citrate
DTXSID50163674
DTXCID2086165