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2-Chloro-1-(3-nitrophenyl)ethanone

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Identification
Molecular formula
C8H6ClNO3
CAS number
3709-33-1
IUPAC name
2-chloro-1-(3-nitrophenyl)ethanone
State
State

At room temperature, 2-chloro-1-(3-nitrophenyl)ethanone is found as a crystalline solid, which can be handled using standard precautions for handling chemicals of this nature.

Melting point (Celsius)
72.00
Melting point (Kelvin)
345.15
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.15
General information
Molecular weight
201.59g/mol
Molar mass
201.5890g/mol
Density
1.3873g/cm3
Appearence

2-Chloro-1-(3-nitrophenyl)ethanone is typically encountered as an off-white to pale yellow crystalline solid. The crystals are often fine to the touch and can vary slightly in shade based on purity.

Comment on solubility

Solubility of 2-chloro-1-(3-nitrophenyl)ethanone

The solubility of 2-chloro-1-(3-nitrophenyl)ethanone can be influenced by several factors, including its molecular structure and the presence of functional groups. This compound, with its chlorinated ethyl ketone moiety and nitro-substituted aromatic ring, exhibits interesting solubility characteristics:

  • Polar Characteristics: The presence of the nitro group (−NO2) and the carbonyl group (C=O) in the structure tends to enhance solubility in polar solvents such as water.
  • Non-Polar Characteristics: In contrast, the aromatic ring may provide some hydrophobic character, influencing the solubility in non-polar organic solvents. Thus, 2-chloro-1-(3-nitrophenyl)ethanone is likely to be:
    • Partially soluble in water
    • More soluble in organic solvents (e.g., ethanol, acetone)
  • Temperature Effects: As with many organic compounds, an increase in temperature may enhance solubility due to increased kinetic energy, facilitating the breakdown of intermolecular forces.

In summary, the solubility of 2-chloro-1-(3-nitrophenyl)ethanone is characterized by a balance between its polar and non-polar attributes, making it a compound of interest for further studies in solubility behavior.

Interesting facts

2-Chloro-1-(3-nitrophenyl)ethanone: An Insightful Overview

2-Chloro-1-(3-nitrophenyl)ethanone is a fascinating chemical compound known for its unique structure and potential applications in various fields. Here are some intriguing facts:

  • Key Functional Groups: This compound features a chlorinated acetophenone structure, which contributes to its reactivity and potential in synthetic chemistry.
  • Di-functional Nature: The presence of both a nitro group and a chloro group allows it to participate in a variety of chemical reactions, making it versatile for organic syntheses.
  • Industrial Relevance: It is studied for its applications in drug synthesis, particularly in creating intermediates for pharmaceuticals due to its unique reactivity.
  • Synthetic Utility: The compound serves as a useful intermediate in the synthesis of other complex molecules, paving the way for new chemical entities.
  • Biological Activity: Investigations into its biological activity are ongoing, as compounds featuring nitro and chloro groups are often found to have interesting pharmacological properties.

In summary, 2-chloro-1-(3-nitrophenyl)ethanone stands out not just for its molecular structure but also for its significance in organic synthesis and medicinal chemistry. Understanding compounds like this one can lead to innovative approaches in designing new materials and drugs, reflecting the creativity and complexity inherent in the field of chemistry.

Synonyms
Acetophenone, 2-chloro-m-nitro-
99-47-8
2-chloro-1-(3-nitrophenyl)ethanone
2-Chloro-m-nitroacetophenone
USAF MA-8
BRN 1958853
alpha-Chloro-m-nitro-acetophenone
3-07-00-00996 (Beilstein Handbook Reference)
SCHEMBL3910668
DTXSID10870438
LBHUVZXFCGZYDL-UHFFFAOYSA-N
alpha-chloro-meta -nitroacetophenone
.alpha.-Chloro-m-nitro-acetophenone
2-CHLORO-3'-NITROACETOPHENONE
AKOS002392958
2-Chloro-1-(3-nitrophenyl)ethan-1-one