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HCFC-123

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Identification
Molecular formula
C2HClF4O
CAS number
306-83-2
IUPAC name
2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-ethane
State
State

HCFC-123 is usually found in a liquid state at room temperature due to its relatively low boiling point. It is nonflammable and exhibits a low vapor pressure, making it a suitable working fluid for various applications, including refrigeration and air conditioning systems.

Melting point (Celsius)
-107.00
Melting point (Kelvin)
166.15
Boiling point (Celsius)
27.20
Boiling point (Kelvin)
300.35
General information
Molecular weight
152.93g/mol
Molar mass
152.9330g/mol
Density
1.4658g/cm3
Appearence

HCFC-123 is a colorless liquid with a faint sweet odor. It is typically free of any visible impurities and remains stable under normal conditions.

Comment on solubility

Solubility of 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-ethane (C2HClF4O)

The solubility characteristics of 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-ethane are particularly intriguing due to the compound's unique molecular structure and the presence of functional groups that influence its interactions with solvents. Key aspects to consider include:

  • Polarity: This compound contains both polar and nonpolar elements, primarily due to the presence of chlorine and fluorine atoms, which typically increase polarity. This suggests that it may be more soluble in polar solvents.
  • Hydrogen Bonding: The difluoromethoxy group can participate in hydrogen bonding, which is favorable for solubility in polar solvents such as water and alcohols.
  • Fluorinated Characteristics: The fluorine atoms enhance stability and may hinder solubility in certain organic solvents due to steric effects and strong intermolecular interactions.
  • Environmental Considerations: Being a halogenated compound, its solubility behavior can also reflect its potential for bioaccumulation or environmental persistence.

In summary, while the exact solubility of 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-ethane would require empirical data, one can reasonably hypothesize that it exhibits moderate solubility in polar solvents while facing challenges in nonpolar environments. Analyzing the compound's solubility behavior can provide insights into its potential applications and environmental impact.

Interesting facts

Discovering 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoro-ethane

2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoro-ethane is a fascinating compound in the world of organofluorine chemistry. This molecular structure is notable for its unique combination of functionalities, making it an interesting subject for both industrial and academic research. Here are some remarkable facts about this compound:

  • Fluorinated Properties: The presence of multiple fluorine atoms creates potent intermolecular interactions, enhancing the compound’s stability and lipophilicity.
  • Application Potential: Its distinct chemical properties make it a candidate for use in pharmaceuticals, agrochemicals, and high-performance solvents.
  • Reactivity and Synthesis: The synthesis of this compound requires precise control due to its reactive chlorinated and difluoromethoxy groups, which can facilitate various substitution reactions.
  • Environmental Impact: The field of organofluorine compounds is often scrutinized due to concerns about the environmental impact of fluorinated compounds, and 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-ethane is no exception.

As noted by chemists studying fluorinated compounds, "The addition of fluorine can significantly change the properties and applications of even the simplest molecular structures." This underscores the importance of compounds like 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-ethane in advancing our understanding of organic chemistry and its practical applications.

Overall, the study of this compound reveals the intricate balance between innovation and environmental stewardship in the field of chemistry.

Synonyms
enflurane
13838-16-9
2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
Methylflurether
Efrane
Ethrane
2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether
Alyrane
Compound 347
Anesthetic 347
Anesthetic Compound No. 347
OHIO 347
Enflurano
Ethane, 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-
Enfluranum
Enfluranum [INN-Latin]
Enflurano [INN-Spanish]
NSC-115944
C 347
Ether, 2-chloro-1,1,2-trifluoroethyl difluoromethyl
CHEBI:4792
DTXSID1020562
91I69L5AY5
MFCD00069095
DTXCID30562
R-E-235CA2
NSC115944
NCGC00167422-01
ENFLURANE (MART.)
ENFLURANE [MART.]
ENFLURANE (USP-RS)
ENFLURANE [USP-RS]
C3H2ClF5O
ENFLURANE (USP IMPURITY)
ENFLURANE [USP IMPURITY]
ENFLURANE (USP MONOGRAPH)
ENFLURANE [USP MONOGRAPH]
(+/-)-2-CHLORO-1,1,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER
ETHANE, 2-CHLORO-1-(DIFLUOROMETHOXY)-1,1,2-TRIFLUORO-, (+/-)-
Ethrane (TN)
CAS-13838-16-9
EINECS 237-553-4
BRN 1903921
UNII-91I69L5AY5
HSDB 7909
Enflurane [Anaesthetics, volatile]
Enflurane [USAN:USP:INN:BAN:JAN]
(+-)-2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether
WLN: GYFXFFOYFF
ENFLURANE [INN]
ENFLURANE [JAN]
ENFLURANE [MI]
ENFLURANE [USAN]
ENFLURANE [VANDF]
(+-)-ENFLURANE
ENFLURANE [WHO-DD]
CHEMBL1257
SCHEMBL61712
Enflurane (JP18/USP/INN)
ENFLURANE [GREEN BOOK]
GTPL7175
ENFLURANE [ORANGE BOOK]
N01AB04
Ethane, 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-, (+-)-
Tox21_112426
Tox21_200166
AKOS015853043
DB00228
FE29162
NSC 115944
Ether,1,2-trifluoroethyl difluoromethyl
NCGC00167422-02
NCGC00257720-01
AS-69470
SY062224
DB-042426
NS00005449
C07516
D00543
D83877
EN300-123045
SBI-0654084.0001
2-Chloro-1,2-trifluoroethyl difluoromethyl ether
2-Chloro-1-(difluoromethoxy)-1,2-trifluoroethane
2-choro-1,1,2-trifluoroethyl difluoromethyl ether
Q416740
SR-01000944966
2-Chloro-1,1,2-difluoroethane, 1-difluoromethoxy-
SR-01000944966-1
2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-ethane
BRD-A51831848-001-01-7
Z1255360592
(2RS)-2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
2-CHLORO-1,1,2-TRIFLUORO-1-DIFLUOROMETHOXYETHANE
2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether, AldrichCPR
2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether;4-Chloro-1H,4H-perfluoro(2-oxabutane)
237-553-4