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4-Chloro-3-nitroanisole

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Identification
Molecular formula
C7H6ClNO3
CAS number
607-57-8
IUPAC name
2-chloro-1-methoxy-4-nitro-benzene
State
State

At room temperature, 4-Chloro-3-nitroanisole is in the solid state, specifically forming crystalline solids.

Melting point (Celsius)
65.00
Melting point (Kelvin)
338.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
187.57g/mol
Molar mass
187.5730g/mol
Density
1.3530g/cm3
Appearence

4-Chloro-3-nitroanisole is typically a yellow crystalline solid. The crystals are often needle-like and can have a shiny or glossy appearance. The compound's yellow color is due to the presence of the nitro group in its structure, which is characteristic of many nitroaromatics.

Comment on solubility

Solubility of 2-chloro-1-methoxy-4-nitro-benzene

2-chloro-1-methoxy-4-nitro-benzene, with the chemical formula C7H6ClNO3, presents an interesting profile regarding solubility. This compound showcases specific solubility characteristics, primarily influenced by its functional groups. Consider the following aspects:

  • Polarity: The presence of the nitro group (-NO2) and the methoxy group (-OCH3) contributes to the overall polarity of the molecule. This can enhance solubility in polar solvents.
  • Solvent Interaction: 2-chloro-1-methoxy-4-nitro-benzene is typically soluble in organic solvents such as ethanol, ether, and chloroform, but may exhibit limited solubility in water due to the overall hydrophobic nature of the benzene ring.
  • Temperature Effects: Like many compounds, the solubility of 2-chloro-1-methoxy-4-nitro-benzene can increase with temperature, making it more soluble in hot solvents than in cold.

In conclusion, while this compound is not highly soluble in water, its solubility in organic solvents allows for versatile applications in chemical processes. Understanding the solubility behavior can aid in its practical uses and synthesis.

Interesting facts

Interesting Facts about 2-Chloro-1-methoxy-4-nitro-benzene

2-Chloro-1-methoxy-4-nitro-benzene is a fascinating compound with various applications, especially in the field of organic chemistry. Here are some interesting insights:

  • Chemical Structure: This compound is an example of a substituted benzene. The presence of various functional groups, such as the –Cl (chloro), –OCH3 (methoxy), and –NO2 (nitro), makes it a versatile compound for chemical reactions.
  • Applications: It is widely used as an intermediate in the synthesis of dyes, pharmaceuticals, and other organic compounds. Its unique structure allows it to participate in electrophilic and nucleophilic substitution reactions.
  • Environmental Impact: Compounds like 2-chloro-1-methoxy-4-nitro-benzene can pose environmental risks due to their potential toxicity. Understanding its behavior in the environment is crucial for assessing its ecological impact.
  • Biochemistry: The nitro group in this compound can undergo reduction in biological systems, which is a significant pathway in the metabolism of nitroaromatic compounds. Studying these metabolic pathways is important in pharmacology and toxicology.
  • Safety Precautions: Working with chloro and nitro compounds requires strict adherence to safety protocols, as they can be hazardous. Personal protective equipment and proper ventilation are essential during experiments.

In summary, 2-chloro-1-methoxy-4-nitro-benzene is more than just a chemical formula; it is a gateway to understanding complex organic reactions and their implications in both industrial applications and environmental science. As you explore this compound, remember the interconnectedness of chemistry, biology, and environmental health.

Synonyms
2-Chloro-4-nitroanisole
4920-79-0
2-Chloro-1-methoxy-4-nitrobenzene
Chloronitroanisole
Benzene, 2-chloro-1-methoxy-4-nitro-
Orthochloroparanitroanisole
2-Chloro-4-nitro-anisole
3-Chloro-4-methoxynitrobenzene
ANISOLE, 2-CHLORO-4-NITRO-
EINECS 225-547-4
BRN 2209429
O-chloro-p-nitroanisole
DLJPNXLHWMRQIQ-UHFFFAOYSA-
DTXSID50197717
4-06-00-01354 (Beilstein Handbook Reference)
NSC 94734
DTXCID10120208
Benzene, 2-chloro-1-methoxy-4-nitro-(9CI)
225-547-4
dljpnxlhwmrqiq-uhfffaoysa-n
inchi=1/c7h6clno3/c1-12-7-3-2-5(9(10)11)4-6(7)8/h2-4h,1h3
OCNA
MFCD00060681
2-Chloro-4-nitoranisole
SCHEMBL512092
NSC94734
NSC-94734
STK400100
AKOS006230156
DS-12605
SY016352
DB-020836
NS00031869