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Sevoflurane

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Identification
Molecular formula
C4H3ClF2O
CAS number
28523-86-6
IUPAC name
2-chloro-1,1-difluoro-1-methoxy-ethane
State
State

Sevoflurane is a liquid at room temperature and is used extensively as a volatile anesthetic agent in medicine.

Melting point (Celsius)
-115.80
Melting point (Kelvin)
157.35
Boiling point (Celsius)
58.60
Boiling point (Kelvin)
331.75
General information
Molecular weight
200.06g/mol
Molar mass
200.0550g/mol
Density
1.5200g/cm3
Appearence

Sevoflurane is a colorless liquid with a sweet smell. It is non-flammable and non-explosive, making it stable for use as an inhalational anesthetic agent.

Comment on solubility

Solubility of 2-chloro-1,1-difluoro-1-methoxy-ethane

2-chloro-1,1-difluoro-1-methoxy-ethane is a unique compound with interesting solubility characteristics. Its solubility is influenced by the presence of fluorine and chlorine atoms, which can enhance its polarity. Here are some key points regarding its solubility:

  • Polarity: The presence of electronegative halogens (Cl and F) adds to the compound's dipole moment, increasing its ability to dissolve in polar solvents.
  • Solvent Compatibility: This compound is generally more soluble in polar solvents such as water and alcohols due to its polar nature. Hydrocarbons and non-polar solvents might offer limited solubility.
  • Hydrogen Bonding: The methoxy group (-OCH3), can engage in hydrogen bonding, which can further improve solubility in suitable solvents.

In summary, the solubility of 2-chloro-1,1-difluoro-1-methoxy-ethane is affected by various factors including its polarity, the nature of the solvent, and the presence of functional groups that can participate in intermolecular interactions. Thus, one should always consider these aspects when predicting solubility in practical applications.

Interesting facts

Interesting Facts about 2-Chloro-1,1-difluoro-1-methoxy-ethane

2-Chloro-1,1-difluoro-1-methoxy-ethane, often referred to in shorthand as CDFM, is a fascinating compound that serves several intriguing purposes in both industrial and laboratory settings.

Applications

  • Solvent Use: This compound is commonly used as a solvent due to its ability to dissolve a variety of polar and nonpolar substances, making it an essential component in reaction environments.
  • Intermediate in Synthesis: CDFM acts as an important intermediate in the synthesis of various fluorinated organic compounds, which are vital in medicinal chemistry.
  • Potential in Pharmaceuticals: Researchers are exploring its potential applications in the pharmaceutical industry, particularly in the development of new drugs due to the unique properties imparted by its fluorine atoms.

Chemical Properties

The presence of chlorine and fluorine atoms in its structure allows CDFM to exhibit distinctive properties:

  • Fluorine Influence: The electronegativity of fluorine significantly alters chemical reactivity, often leading to higher stability and altered reactivity in organic synthesis.
  • Polar Character: The polar nature of the methoxy group contributes to its solubility profile and reactivity, which chemists can manipulate in various applications.

Safety Considerations

When working with 2-chloro-1,1-difluoro-1-methoxy-ethane, researchers must always adhere to stringent safety protocols:

  • Use Personal Protective Equipment (PPE): Proper lab attire, including gloves and goggles, is crucial to prevent exposure.
  • Ventilation: Conduct syntheses in a well-ventilated area or fume hood due to potential toxicity.

In summary, 2-chloro-1,1-difluoro-1-methoxy-ethane stands out as a compound with diverse applications, particularly in organic synthesis and chemical research. Its intriguing structure and reactivity highlight the importance of fluorinated compounds in advancing various scientific fields.

Synonyms
2-Chloro-1,1-difluoro-1-methoxyethane
428-65-9
ETHANE, 2-CHLORO-1,1-DIFLUORO-1-METHOXY-
BRN 1734832
DTXSID80195488
AKOS006384463