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2-Chlorobenzoxazole

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Identification
Molecular formula
C7H4ClNO
CAS number
38740-82-8
IUPAC name
2-chloro-1,3-benzoxazole
State
State

At room temperature, 2-Chlorobenzoxazole is typically in a solid state as a crystalline powder.

Melting point (Celsius)
30.00
Melting point (Kelvin)
303.15
Boiling point (Celsius)
274.00
Boiling point (Kelvin)
547.15
General information
Molecular weight
155.57g/mol
Molar mass
155.5680g/mol
Density
1.3860g/cm3
Appearence

2-Chlorobenzoxazole appears as a white to off-white crystalline powder. It is a heterocyclic compound composed of a benzene ring fused to an oxazole ring, with a chlorine atom substituting one hydrogen in the benzene ring.

Comment on solubility

Solubility of 2-chloro-1,3-benzoxazole

2-chloro-1,3-benzoxazole presents interesting solubility characteristics that are noteworthy. Generally, this compound is classified as having moderate solubility in organic solvents. Here are some key points:

  • Solvent Compatibility: 2-chloro-1,3-benzoxazole is known to dissolve well in solvents such as dichloromethane and ethanol.
  • Water Solubility: Its solubility in water is very limited, making it somewhat hydrophobic.
  • Temperature Dependence: The solubility can vary with temperature. Higher temperatures may enhance its solubility in organic solvents.
  • Applications in Solutions: Due to its solubility profile, it can often be used in organic synthesis and as a reactant in various chemical reactions.

It is essential to consider that “like dissolves like,” and thus the polar nature of a solvent will heavily influence solubility. As 2-chloro-1,3-benzoxazole is less polar, it is not expected to perform well in polar solvents such as water.


In conclusion, knowing the solubility of 2-chloro-1,3-benzoxazole is crucial for its practical applications in research and industry, influencing choices for solvents in both laboratory and industrial settings.

Interesting facts

Interesting Facts about 2-Chloro-1,3-benzoxazole

2-Chloro-1,3-benzoxazole is a fascinating compound that has captured the interest of chemists and researchers alike. This compound belongs to a class of heterocyclic aromatic compounds, which play a crucial role in various chemical applications. Here are some intriguing aspects of 2-chloro-1,3-benzoxazole:

  • Applications in Medicinal Chemistry: 2-Chloro-1,3-benzoxazole is often used as a building block in the synthesis of pharmaceuticals and biologically active compounds. Its structure allows for the development of new drugs, targeting various diseases.
  • Role in Agrochemicals: This compound is also significant in the agricultural sector, where it is investigated for its potential use in herbicides and pesticides. The unique properties of benzoxazole derivatives can help mitigate crop diseases.
  • Fluorescence Properties: Compounds like 2-chloro-1,3-benzoxazole can exhibit interesting fluorescent properties, making them useful in various imaging applications, particularly in biological studies.
  • Synthetic Versatility: The presence of the chloro group in this compound enables several fascinating reactions that can create new derivatives with modified properties, providing a platform for further chemical exploration.
  • Research Significance: Scientists are excited about the potential of 2-chloro-1,3-benzoxazole in developing materials for electronic devices due to its semiconducting properties. 

In the world of chemistry, every compound has its own story and potential. 2-Chloro-1,3-benzoxazole is no exception, providing opportunities for innovative applications in medicine, agriculture, and material science. As we continue to explore this compound, who knows what new discoveries await us?

Synonyms
2-Chlorobenzoxazole
615-18-9
2-Chloro-1,3-benzoxazole
BENZOXAZOLE, 2-CHLORO-
2-chlorobenzo[d]oxazole
OFH5RW45PA
NSC 8439
EINECS 210-414-5
BRN 0115982
2-chlorobenzo(d)oxazole
NSC-8439
UNII-OFH5RW45PA
DTXSID5060643
2-27-00-00017 (Beilstein Handbook Reference)
DTXCID0043052
210-414-5
bbvqdwdbtwsghq-uhfffaoysa-n
inchi=1/c7h4clno/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4
MFCD00005766
2-chloro-benzoxazole
Benzoxazole, chloro-
Chlorobenzoxazole
2-chlorobenzoxazol
NSC8439
2-chlorobenzooxazole
2-chloro benzoxazole
2-chloro-benzooxazole
2-Chlorobenzoxazole, 99%
2-chloro-1,3-benzooxazole
SCHEMBL105029
2-Chloro-1,3-benzoxazole #
SCHEMBL9430597
WLN: T56 BN DOJ CG
CHEMBL4575218
ALBB-021333
BCP27388
STR05753
AKOS000117946
AB00524
AC-4801
FS-3177
HY-W019606
BP-13047
SY010741
DB-011005
CS-0030558
NS00034713
EN300-27567
F3284-7644
Z235343929
T2U