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Methapyrilene hydrochloride

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Identification
Molecular formula
C17H21Cl2N
CAS number
135-23-9
IUPAC name
[2-chloro-2-(2-naphthyl)ethyl]-isopropyl-ammonium;chloride
State
State

At room temperature, methapyrilene hydrochloride is typically in a solid state as it is a crystalline powder.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
308.26g/mol
Molar mass
308.8400g/mol
Density
1.0863g/cm3
Appearence

Methapyrilene hydrochloride appears as a white to off-white crystalline powder. It is usually used in its salt form due to better solubility in water compared to its base form.

Comment on solubility

Solubility of [2-chloro-2-(2-naphthyl)ethyl]-isopropyl-ammonium;chloride

The solubility of the compound [2-chloro-2-(2-naphthyl)ethyl]-isopropyl-ammonium;chloride in various solvents can greatly influence its applications in chemical processes and formulations. Solubility is a key factor that determines how effectively a substance can be utilized.

In assessing its solubility, consider the following:

  • Aqueous Solubility: Being an ammonium salt, this compound is likely to exhibit a degree of solubility in water. However, the presence of the 2-naphthyl group may introduce hydrophobic characteristics, potentially reducing its overall water solubility.
  • Organic Solvents: The naphthalene moiety may enhance solubility in organic solvents such as ethanol or acetone. Consequently, exploring various organic solvents may yield better solubility results.
  • Temperature Dependence: Solubility may vary with temperature; warming the solvent can often increase the solubility of compounds, particularly those with complex structures like this one.

It is essential to note that complex ionization effects may also play a role in its behavior in solution. As stated, "solubility is not just a property but a reflection of the balance between attractive and repulsive forces" within the compound and with the solvent. Thus, obtaining empirical solubility data through experimentation is crucial for a comprehensive understanding of how this compound behaves in different environments.

In summary, while [2-chloro-2-(2-naphthyl)ethyl]-isopropyl-ammonium;chloride is likely to be somewhat soluble in water, it may exhibit greater solubility in various organic solvents due to its structural features. Understanding these solubility dynamics is vital for its practical applications.

Interesting facts

Interesting Facts about [2-chloro-2-(2-naphthyl)ethyl]-isopropyl-ammonium;chloride

This intriguing compound, known for its unique structure, has fascinating implications and uses in various fields of chemistry and pharmacology. Here are some noteworthy points about this compound:

  • Structure and Composition: The compound features a chlorinated 2-naphthyl moiety, which contributes to its potential biological activity. The presence of an isopropylammonium group enhances its ability to interact with biological systems.
  • Pharmacological Potential: Compounds similar to this one have been explored for their role as antihistamines and antipsychotics, illustrating how structural modifications can lead to varied pharmacological effects.
  • Naphthalene Basis: The naphthyl group in the structure is derived from naphthalene, a compound known for its distinct aroma and use in mothballs. This aromatic structure provides hydrophobic characteristics, influencing the compound's interaction with lipid membranes.
  • Quaternary Ammonium Compound: Being a quaternary ammonium salt, this compound can exhibit surfactant properties, making it useful in formulations where surface activity is required.
  • Research Interest: Scientists are continually exploring the synthesis and reactivity of such compounds, leading to potential new applications in drug discovery and design.

In summary, [2-chloro-2-(2-naphthyl)ethyl]-isopropyl-ammonium;chloride is not only a compound of chemical interest but also a candidate for various applications in medicinal chemistry, offering exciting opportunities for future research.

Synonyms
Ici 42464
20794-96-1
UD80IK2VM0
2-NAPHTHALENEETHYLAMINE, beta-CHLORO-N-ISOPROPYL-, HYDROCHLORIDE
ICI-42464
2-(gamma-chloro-beta-isopropylamino)ethylnaphthalene.HCl
2-(1-CHLORO-2-ISOPROPYLAMINOETHYL)NAPHTHALENE HYDROCHLORIDE
RefChem:147639
beta-Chloro-N-isopropyl-2-naphthaleneethanamine hydrochloride
beta-Chloro-N-isopropyl-2-naphthaleneethylamine hydrochloride
2-(alpha-Chloro-beta-isopropylamine)ethylnaphthalene hydrochloride
(2-chloro-2-naphthalen-2-ylethyl)-propan-2-ylazanium;chloride
UNII-UD80IK2VM0
2-(gamma-Chloro-beta-isopropylamino)ethylnaphthalene hydrochloride