Skip to main content

Mitoxantrone

ADVERTISEMENT
Identification
Molecular formula
C22H28ClN3O4
CAS number
65271-80-9
IUPAC name
2-chloro-3-[3-(dimethylamino)propylamino]naphthalene-1,4-dione
State
State

Mitoxantrone is a solid at room temperature. It is commonly handled as a powder in its pharmaceutical form and is reconstituted or dissolved for medical administration.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.15
Boiling point (Celsius)
552.40
Boiling point (Kelvin)
825.55
General information
Molecular weight
518.93g/mol
Molar mass
518.5000g/mol
Density
1.3000g/cm3
Appearence

Mitoxantrone appears as a dark blue to purple crystalline powder. The crystals are defined and can vary in size. It also typically presents in a more compressed form for pharmaceutical usage.

Comment on solubility

Solubility of 2-chloro-3-[3-(dimethylamino)propylamino]naphthalene-1,4-dione

The solubility of 2-chloro-3-[3-(dimethylamino)propylamino]naphthalene-1,4-dione in various solvents can be influenced by its chemical structure and polarity. This compound exhibits certain characteristics that may impact its solubility:

  • Polarity: The presence of a dimethylamino group suggests some degree of polarity, which can enhance solubility in polar solvents.
  • Hydrogen Bonding: This molecule can potentially engage in hydrogen bonding due to the amine functionalities, aiding in solubility in appropriate solvents.
  • Solvent Compatibility: Commonly, compounds similar to this one are soluble in polar organic solvents such as alcohols or dimethyl sulfoxide (DMSO), but may have limited solubility in nonpolar solvents.

However, it is essential to note that actual solubility can vary significantly based on temperature and specific solvent parameters. Experimental data provides the most accurate insight into solubility characteristics. As stated in the literature, "the solubility of a compound is a fundamental property impacting its bioavailability and overall reactivity," making it crucial for applications involving this complex organic compound.

Interesting facts

Interesting Facts about 2-chloro-3-[3-(dimethylamino)propylamino]naphthalene-1,4-dione

2-chloro-3-[3-(dimethylamino)propylamino]naphthalene-1,4-dione is a fascinating compound with notable properties and applications. Below are some intriguing points to consider:

  • Structure and Functionality: The compound features a complex structure including a naphthalene ring, which is known for its stability and unique electronic properties. This aromatic system makes it particularly interesting for various chemical reactions.
  • Biological Significance: Compounds that contain a naphthalene core have been widely studied for their pharmacological properties, including anti-inflammatory and anticancer activities. The addition of functional groups, such as the dimethylamino propylamino chain, can enhance its biological activity.
  • Applications in Research: Due to the presence of the chlorine substituent and the amino groups, this compound can serve as a valuable intermediate in synthetic organic chemistry, potentially leading to the development of new pharmaceuticals.
  • Solubility Variations: The nature of the substituents plays a crucial role in determining the solubility of this compound in various solvents, which can impact its usability in different chemical environments.

In the words of a renowned chemist, "The power of a compound resides not only in its structure but also in the potential innovations it can inspire." This statement is especially true for 2-chloro-3-[3-(dimethylamino)propylamino]naphthalene-1,4-dione, highlighting its role as a candidate for future explorations in the realms of medicinal chemistry and materials science.

This compound exemplifies the beauty of chemical diversity and its implications in scientific advancements. As research continues to evolve, compounds like this will undoubtedly play pivotal roles in the development of new therapeutic agents.

Synonyms
22272-09-9
D4KEG8DS4C
1,4-NAPHTHOQUINONE, 2-CHLORO-3-(3-(DIMETHYLAMINO)PROPYLAMINO)-
NSC39349
2-Chloro-3-(3-dimethylaminopropylamino)-1,4-naphthoquinone
NSC-39349
DTXSID20176817
2-Chloro-3-((3-(dimethylamino)propyl)amino)-1,4-naphthalenedione
NSC 39349
BRN 3096580
2-chloro-3-[3-(dimethylamino)propylamino]naphthalene-1,4-dione
UNII-D4KEG8DS4C
RefChem:1062748
CHEMBL4286829
DTXCID6099308
1, 2-chloro-3-(3-(dimethylamino)propylamino)-
1, 2-chloro-3-[[3-(dimethylamino)propyl]amino]-
2-Chloro-3-{[3-(dimethylamino)propyl]amino}naphthoquinone