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2-Chloro-3-(3-morpholinopropylamino)naphthalene-1,4-dione

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Identification
Molecular formula
C17H19ClN2O3
CAS number
50551-59-8
IUPAC name
2-chloro-3-(3-morpholinopropylamino)naphthalene-1,4-dione
State
State

At room temperature, 2-Chloro-3-(3-morpholinopropylamino)naphthalene-1,4-dione is in a solid crystalline state. It should be handled with care as with many organic compounds and stored in a cool, dry place.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
358.82g/mol
Molar mass
358.8220g/mol
Density
1.3520g/cm3
Appearence

2-Chloro-3-(3-morpholinopropylamino)naphthalene-1,4-dione typically appears as a crystalline solid. The color can vary based on its purity and physical form, but it is often found as a yellow to brown solid. This compound is usually stable under recommended storage conditions.

Comment on solubility

Solubility of 2-chloro-3-(3-morpholinopropylamino)naphthalene-1,4-dione

The solubility of 2-chloro-3-(3-morpholinopropylamino)naphthalene-1,4-dione in various solvents is an important characteristic to consider for its applications in both research and industry. This compound exhibits a unique structure that can significantly influence its solubility properties.

Factors Affecting Solubility

Several factors determine the solubility of this compound:

  • Polarity of Solvent: The polarity of the solvent plays a crucial role; polar solvents, such as water, may not solubilize this compound effectively due to its nonpolar regions.
  • Hydrophobic Interactions: The naphthalene ring contributes to hydrophobic interactions, which can limit solubility in aqueous environments.
  • Functional Groups: The presence of the chlorinated and morpholino groups may provide modest solubility in organic solvents like methanol or ethanol.

General Solubility Profile

In general, this compound is expected to have:

  • Low solubility in water due to the hydrophobic naphthalene core.
  • Moderate solubility in organic solvents such as DMSO or acetonitrile, driven by its polar functional groups.

Overall, the solubility of 2-chloro-3-(3-morpholinopropylamino)naphthalene-1,4-dione is markedly influenced by both its structural features and the choice of solvent. Understanding these solubility characteristics is essential for optimizing its use in various chemical processes and applications.

Interesting facts

Interesting Facts about 2-Chloro-3-(3-morpholinopropylamino)naphthalene-1,4-dione

2-Chloro-3-(3-morpholinopropylamino)naphthalene-1,4-dione is a fascinating compound that straddles the intersection of synthetic organic chemistry and medicinal chemistry. Here are some intriguing aspects:

  • Structure and Function: The naphthalene skeleton, characterized by two fused aromatic rings, is known for its stability and significant role in organic reactions. The presence of the choro and morpholinopropylamino substituents introduces diverse reactivity profiles, making this compound a key player in developing new therapeutic agents.
  • Biological Relevance: Compounds related to naphthalene-1,4-dione are often investigated for their biological activities, including antimicrobial and anticancer properties. The modification of the naphthalene ring can lead to varying biological outcomes, enhancing the compound's potential as a pharmaceutical agent.
  • Research Potential: Scientists are intrigued by how this compound can serve as a scaffold for drug development. Its structure allows for multiple functionalization points, facilitating the synthesis of numerous derivatives that could be explored for a range of biological applications.
  • Mechanistic Insights: Understanding the mechanism of action of naphthalene derivatives is crucial. Researchers often study how structural modifications influence reactivity and interaction with biological targets, which can lead to novel therapeutic pathways.
  • In a Inhibitory Role: Similar compounds have been observed to act as enzymatic inhibitors. Investigating the inhibitory capacity of this compound could provide insights into its potential use in treating diseases arising from enzyme dysregulation.

In the words of chemists, "The synthesis of a new compound is often the first step towards unveiling its myriad of potentials." 2-Chloro-3-(3-morpholinopropylamino)naphthalene-1,4-dione exemplifies how structural ingenuity in chemistry can lead to groundbreaking discoveries that impact our understanding of biology and medicine.

Synonyms
22295-80-3
2-Chloro-3-(3-morpholinopropylamino)-1,4-naphthoquinone
NSC91758
1,4-NAPHTHOQUINONE, 2-CHLORO-3-((3-MORPHOLINOPROPYL)AMINO)-
MLS002695090
DTXSID70176842
NSC 91758
BRN 1588143
RefChem:1053341
NCIOpen2_009798
SCHEMBL6507746
CHEMBL1701309
DTXCID3099333
2-Chloro-3-[(3-morpholinopropyl)amino]-1,4-naphthoquinone
HMS3079E19
NSC-91758
SMR001561002
DS-000865
WLN: L66 BV EVJ CG DM3- AT6N DOTJ
1, 2-chloro-3-[(3-morpholinopropyl)amino]-
2-chloro-3-(3-morpholinopropylamino)naphthalene-1,4-dione
2-Chloro-3-[(3-morpholin-4-ylpropyl)amino]naphthoquinone
1,4-NAPHTHALENEDIONE,2-CHLORO-3-[[3-(4-MORPHOLINYL)PROPYL]AMINO]-