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Clofibric Acid

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Identification
Molecular formula
C13H9Cl2O4S
CAS number
88283-41-4
IUPAC name
2-chloro-4-[3-(3-chloro-4-hydroxy-phenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol
State
State

At room temperature, clofibric acid exists in a solid state. It is stable under normal conditions and remains solid in its pure form.

Melting point (Celsius)
146.50
Melting point (Kelvin)
419.65
Boiling point (Celsius)
415.20
Boiling point (Kelvin)
688.35
General information
Molecular weight
280.18g/mol
Molar mass
280.6860g/mol
Density
1.6810g/cm3
Appearence

Clofibric acid appears as a white crystalline solid. It is a chlorophenyl derivative with a phenolic structure, giving it a characteristic aromatic appearance. It is generally odorless and exhibits a crystalline sheen.

Comment on solubility

Solubility of 2-chloro-4-[3-(3-chloro-4-hydroxy-phenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol

The solubility of the compound 2-chloro-4-[3-(3-chloro-4-hydroxy-phenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol can be quite complex due to its intricate structure and the presence of various functional groups. Here's what you need to know:

  • Aqueous Solubility: This compound may demonstrate limited solubility in water, primarily due to its hydrophobic aromatic components.
  • Organic Solvents: It is likely to be more soluble in organic solvents such as methanol, ethanol, and acetone. This is common for compounds featuring aromatic rings and dioxo functionalities.
  • pH Dependence: The solubility may vary with pH; the presence of hydroxyl groups can influence solubility in acidic or basic environments. As a rule of thumb: acidic conditions can enhance solubility for compounds with basic nitrogen functionalities.

To sum up, the solubility of 2-chloro-4-[3-(3-chloro-4-hydroxy-phenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol is likely to be influenced significantly by the solvent choice, with better solubility anticipated in organic solvents compared to aqueous solutions. Understanding these solubility characteristics is key for various applications, including pharmaceutical formulations and chemical reactions.

Interesting facts

Interesting Facts About 2-Chloro-4-[3-(3-chloro-4-hydroxy-phenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol

This fascinating compound, known as 2-Chloro-4-[3-(3-chloro-4-hydroxy-phenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol, is notable for its complex structure and potential applications in medicinal chemistry.

Chemical Significance

  • Chlorinated Phenols: The presence of chlorine substituents plays a critical role in the compound's biological activity, often enhancing its reactivity and solubility in organic solvents.
  • Benzoxathiol Derivative: This compound features a benzoxathiol core, which is known for antioxidant properties and may have implications in therapies against oxidative stress-related diseases.
  • Potential Anticancer Activity: Research indicates that analogs of this compound may exhibit anticancer properties, making it a candidate for further pharmacological studies.

Applications in Research

This compound is often utilized in various fields of research, including:

  • Pharmaceutical Research: As scientists delve deeper into its properties, it may contribute to developing new therapeutic agents.
  • Toxicology: Understanding its effects on biological systems helps assess the safety of chlorinated compounds.
  • Material Science: Its unique structure may lead to applications in creating novel materials with specific characteristics.

In summary, 2-Chloro-4-[3-(3-chloro-4-hydroxy-phenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol serves as a prime example of how complex chemical structures can open up new avenues for scientific exploration and potential therapeutic applications.

Synonyms
CHLOROPHENOL RED
4430-20-0
Chlorphenol Red
Chlorphenolsulfonphthalein
Dichlorophenolsulfonephthalein
Phenol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[2-chloro-
Chlorophenol red indicator
P3S5KH33EA
3',3''-Dichlorophenolsulfonphthalein
NSC 7828
NSC-7828
EINECS 224-619-2
Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis[2-chloro-, S,S-dioxide
DTXSID4063450
Phenol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis(2-chloro-
3,3-bis(3-chloro-4-hydroxyphenyl)-3H-2,1$l^{6}-benzoxathiole-1,1-dione
4,4'-(1,1-Dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[2-chlorophenol]
Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis(2-chloro-, S,S-dioxide
2-Chloro-4-[3-(3-chloro-4-hydroxy-phenyl)-1,1-dioxo-benzo[c]oxathiol-3-yl]phenol
3,3-bis(3-chloro-4-hydroxyphenyl)-3H-2,1$l^(6)-benzoxathiole-1,1-dione
4,4'-(1,1-Dioxido-3H-2,1-benzoxathiol-3-ylidene)bis(2-chlorophenol)
2-Chloro-4-(3-(3-chloro-4-hydroxy-phenyl)-1,1-dioxo-benzo(c)oxathiol-3-yl)phenol
DTXCID3040302
3',3''Dichlorophenolsulfonphthalein
4,4'(3H2,1Benzoxathiol3ylidene)bis(2chlorophenol) S,Sdioxide
Phenol, 4,4'(1,1dioxido3H2,1benzoxathiol3ylidene)bis(2chloro
Phenol, 4,4'(3H2,1benzoxathiol3ylidene)bis(2chloro, S,Sdioxide (8CI)
Phenol, 4,4'(3H2,1benzoxathiol3ylidene)bis(2chloro, S,Sdioxide (8CI)(9CI)
Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis(2-chloro-, S,S-dioxide (8CI)
Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis(2-chloro-, S,S-dioxide (8CI)(9CI)
224-619-2
wwaabjgnhfgxsj-uhfffaoysa-n
3,3-Bis(3-chloro-4-hydroxyphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide
3',3'-Dichlorophenolsulfonaphthalein
MFCD00005877
NSC7828
2-chloro-4-[3-(3-chloro-4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol
3,3-bis(3-chloro-4-hydroxyphenyl)-3H-2,1??-benzoxathiole-1,1-dione
3',3''-Dichlorophenol- sulfonphthalein
UNII-P3S5KH33EA
SCHEMBL56518
Chlorophenol Red, indicator grade
3,3'-Dichlorophenolsulfonephthalein
HY-D0013
3,3-bis(3-chloro-4-hydroxyphenyl)benzo[c]1,2-oxathiolene-1,1-dione
AC-252
AKOS015896065
FC11148
2-chloro-4-[3-(3-chloro-4-hydroxy-phenyl)-1,1-dioxo-2,1$l^{6}-benzoxathiol-3-yl]phenol
AS-72514
3',3''-Dichlorophenylsulfonphthalein; CPR
CS-0009909
NS00022193
Q410281
3,3-Bis(3-chloro-4-hydroxyphenyl)3H-2,1-benzoxathiole S,S-dioxide
4,4'-(3H-2,1-Benzoxathiol-3-ylidene)bis[2-chlorophenol], 9CI
3,3-bis(3-chloro-4-hydroxyphenyl)-3H-2,1lambda6-benzoxathiole-1,1-dione
3,3-Bis(3-chloro-4-hydroxyphenyl)-3H-benzo[c][1,2]oxathiole1,1-dioxide
4,4'-(3H-2,1-Benzoxathiol-3-ylidene)bis(2-chlorophenol) S,S-dioxide
4,4-(1,1-Dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[2-chlorophenol]
Phenol,4'-(3H-2,1-benzoxathiol-3-ylidene)bis[2-chloro-, S,S-dioxide
2-chloro-4-[3-(3-chloro-4-hydroxyphenyl)-1,1-dioxo-2,1$l^{6-benzoxathiol-3-yl]phenol