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Chloro-hydroxy-methoxybenzaldehyde

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Identification
Molecular formula
C8H7ClO3
CAS number
126941-87-9
IUPAC name
2-chloro-4-hydroxy-5-methoxy-benzaldehyde
State
State

At room temperature, this compound is typically in a solid state. Its stability and crystalline nature make it suitable for various chemical syntheses and applications.

Melting point (Celsius)
97.00
Melting point (Kelvin)
370.15
Boiling point (Celsius)
341.40
Boiling point (Kelvin)
614.55
General information
Molecular weight
186.59g/mol
Molar mass
186.5830g/mol
Density
1.3945g/cm3
Appearence

The compound is typically a white to beige crystalline solid. It presents a crystalline structure and is commonly found in powder form for commercial and laboratory purposes.

Comment on solubility

Solubility of 2-chloro-4-hydroxy-5-methoxy-benzaldehyde

The solubility of 2-chloro-4-hydroxy-5-methoxy-benzaldehyde can be influenced by several factors. This compound is primarily organic in nature, containing both polar and non-polar functional groups. As a result, its solubility can vary significantly depending on the solvent used. Here are some key points regarding its solubility:

  • Polar solvents: The presence of the hydroxyl (-OH) group enhances the solubility of the compound in polar solvents such as water. However, overall, the compound may display limited solubility due to the bulky methoxy (-OCH3) and chloro (-Cl) substituents.
  • Non-polar solvents: Non-polar solvents, such as hexane or toluene, are likely to provide better solubility due to the more substantial hydrophobic character caused by the aromatic ring and methoxy group.
  • Temperature effect: Generally, solubility can increase with temperature; thus, warming the solvent may help improve the dissolution of this compound.
  • Concentration considerations: At higher concentrations, the solubility of the compound will also depend on the specific interactions between solute molecules, which can lead to the formation of clusters in the solution.

In summary, while 2-chloro-4-hydroxy-5-methoxy-benzaldehyde exhibits variable solubility characteristics based on the chosen solvent, one can expect it to be more soluble in non-polar media compared to polar solvents. As always, it is advisable to conduct solubility tests under controlled conditions to determine the optimal solvent for any practical applications.

Interesting facts

Interesting Facts about 2-Chloro-4-hydroxy-5-methoxy-benzaldehyde

2-Chloro-4-hydroxy-5-methoxy-benzaldehyde is a fascinating compound that combines the structures of both an aromatic aldehyde and substituted phenols, revealing a range of unique characteristics and applications. Here are some noteworthy points about this compound:

  • Structure and Functional Groups: This compound features a benzene ring with three distinct substituents: a −Cl (chlorine) atom, a −OH (hydroxy) group, and a −OCH3 (methoxy) group. These functional groups each contribute to the compound's chemical reactivity and physical properties.
  • Biological Activity: Research indicates that various benzaldehyde derivatives, including this one, can exhibit significant biological activity. They may have potential applications in pharmaceuticals, particularly in *antioxidant* or *antimicrobial* formulations.
  • Flavor and Fragrance Industry: Aromatic aldehydes are often central to the production of flavors and fragrances. The unique structure of 2-chloro-4-hydroxy-5-methoxy-benzaldehyde could enhance formulations, providing specific notes that are desirable in perfumes and food products.
  • Synthesis Considerations: The synthesis of this compound may involve sophisticated organic reactions, including halogenation and functional group modifications. Understanding these reactions is critical for chemists aiming to design similar compounds.
  • Research Potential: Given its unique structure, this compound could serve as a lead compound in the synthesis of other derivatives with optimized properties. Chemists often explore similar structural motifs for developing new materials.

In conclusion, 2-chloro-4-hydroxy-5-methoxy-benzaldehyde is not just an ordinary compound; its rich structural characteristics and potential for *biological and industrial applications* make it a significant subject of study in organic and medicinal chemistry.

Synonyms
2-CHLORO-4-HYDROXY-5-METHOXYBENZALDEHYDE
846-462-4
18268-76-3
6-Chlorovanillin
2-Chloro-4-hydroxy-5-methoxy-benzaldehyde
Benzaldehyde, 2-chloro-4-hydroxy-5-methoxy-
MFCD02379943
2JYJ2LFP3W
NSC-95796
NSC95796
NSC 95796
Vanillin, 6-chloro-
UNII-2JYJ2LFP3W
SCHEMBL1054210
DTXSID7075139
ZOKLABLCKDZYOP-UHFFFAOYSA-N
TAA26876
SBB010751
STK397249
AKOS000104246
HY-W077917
BS-35793
DB-027865
CS-0116503
ST45059777
EN300-332881
G54997
Z274515356