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2-Chloro-4-methylaniline

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Identification
Molecular formula
C7H8ClN
CAS number
95-69-2
IUPAC name
2-chloro-4-methyl-aniline
State
State

At room temperature, 2-chloro-4-methylaniline typically exists as a solid.

Melting point (Celsius)
27.00
Melting point (Kelvin)
300.15
Boiling point (Celsius)
234.00
Boiling point (Kelvin)
507.15
General information
Molecular weight
141.59g/mol
Molar mass
141.5920g/mol
Density
1.1872g/cm3
Appearence

2-Chloro-4-methylaniline is a pale yellow to brown solid that may appear in crystalline form. The compound can darken on exposure to air and light.

Comment on solubility

Solubility of 2-chloro-4-methyl-aniline

2-chloro-4-methyl-aniline, often represented by its chemical formula C7H9ClN, is an organic compound with varied solubility characteristics depending on the solvent used and the temperature.

In general, the solubility of 2-chloro-4-methyl-aniline can be summarized as follows:

  • Water: This compound has low solubility in water. The presence of both hydrophobic (the aromatic ring and the methyl group) and hydrophilic (the amino group) elements contribute to its limited interaction with water molecules.
  • Organic Solvents: 2-chloro-4-methyl-aniline is soluble in a range of organic solvents such as ethanol, methanol, and acetone. This is primarily due to its nonpolar molecular structure, which allows for better interactions within nonpolar solvents.
  • Influence of Temperature: The solubility of this compound may increase with temperature, a common characteristic of many solids in liquid solutions.

“Like dissolves like” is a principle applicable here. The nature of the solvent significantly affects the solubility of 2-chloro-4-methyl-aniline. More polar solvents enhance its solubility compared to nonpolar environments.

In conclusion, while 2-chloro-4-methyl-aniline demonstrates some solubility in organic solvents, its interaction with water is limited, underscoring the complexity of solute-solvent interactions in this compound.

Interesting facts

Interesting Facts about 2-chloro-4-methyl-aniline

2-chloro-4-methyl-aniline is a fascinating aromatic amine that belongs to a class of compounds known for their diverse applications in various fields. This compound is primarily known for its role in the synthesis of dyes and pigments, which are essential in the textile and paint industries.

Chemical Structure and Properties

  • The structure of 2-chloro-4-methyl-aniline consists of a benzene ring with a chlorine atom and a methyl group attached to the aniline nitrogen. This specific arrangement imparts unique chemical properties to the compound.
  • Due to the presence of the chlorine substituent, this compound exhibits interesting reactivity patterns, especially in electrophilic substitution reactions.

Applications

  1. Dyes and Pigments: It serves as an important intermediate in the manufacturing of azo dyes, which are widely used in textiles.
  2. Pharmaceuticals: Some derivatives of 2-chloro-4-methyl-aniline have been explored for their potential medicinal properties.
  3. Research Tool: Its reactivity makes it valuable in chemical synthesis and research for developing new compounds.

Toxicity and Safety

It’s worth noting that 2-chloro-4-methyl-aniline is classified as a hazardous substance. Thus, safety precautions should be taken while handling it. Recommended practices include:

  • Wearing appropriate personal protective equipment (PPE), including gloves and goggles.
  • Working in a well-ventilated area or fume hood to minimize inhalation risks.

In summary, 2-chloro-4-methyl-aniline is more than just a chemical; it is a compound laden with potential applications and intriguing reactivity that continues to capture the interest of scientists and researchers alike.

Synonyms
2-Chloro-4-methylaniline
615-65-6
2-CHLORO-P-TOLUIDINE
Benzenamine, 2-chloro-4-methyl-
4-Amino-3-chlorotoluene
p-Toluidine, 2-chloro-
4-Methyl-2-chloroaniline
2-Chlor-4-toluidin
NSC 60120
2-Chlor-4-toluidin [Czech]
CCRIS 2887
HSDB 2059
3-Chloro-4-aminotoluene
1-amino-2-chloro-4-methylbenzene
EINECS 210-440-7
K59ISJ2KO1
BRN 0774514
NSC-60120
DTXSID3022083
3-12-00-02152 (Beilstein Handbook Reference)
2-CHLORO-P-TOLUIDINE [HSDB]
(2-CHLORO-4-METHYLPHENYL)AMINE
2-CHLOR-4-TOLUIDIN (CZECH)
2Chlor4toluidin
pToluidine, 2chloro
2Chloro4methylaniline
4Methyl2chloroaniline
Benzenamine, 2chloro4methyl
DTXCID802083
UN3429
210-440-7
inchi=1/c7h8cln/c1-5-2-3-7(9)6(8)4-5/h2-4h,9h2,1h
2-chloro-4-methyl-aniline
MFCD00007666
2-chloro-4-methylphenylamine
UNII-K59ISJ2KO1
2-chloro-4-methyl aniline
2-CHLORO-4-METHYLANILINE HYDROCHLORIDE
2-Chloro-4-methyl-phenylamine
NSC60120
2-Chlor-p-toluidin
2-choro-4-methylaniline
4-amino-3-chloro-toluene
2-Chloro-4-methylbenzamine
WLN: ZR BG D1
2-chloro-4-methylbenzenamine
2-chloranyl-4-methyl-aniline
SCHEMBL172051
2-Chloro-4-methylaniline, 98%
STL163411
AKOS000113146
CCG-302526
CS-W018296
FC05832
PS-3795
NCGC00166060-01
AC-23555
SY013538
DB-024170
A8535
NS00005065
EN300-19674
A833307
Q27281976
F0001-1625
Z104474672