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2-Chloro-4-nitrobenzoic acid

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Identification
Molecular formula
C7H4ClNO4
CAS number
2516-96-3
IUPAC name
2-chloro-4-nitro-benzoic acid
State
State

At room temperature, 2-chloro-4-nitrobenzoic acid is in a solid state, typically forming as crystalline yellow solids. It is usually stored in a dry environment to maintain its stability.

Melting point (Celsius)
242.00
Melting point (Kelvin)
515.15
Boiling point (Celsius)
-1.00
Boiling point (Kelvin)
-1.00
General information
Molecular weight
201.56g/mol
Molar mass
201.5600g/mol
Density
1.6184g/cm3
Appearence

2-Chloro-4-nitrobenzoic acid is a yellow crystalline solid. Its appearance can vary based on purity and specific sample conditions, but it typically exists as well-formed yellow crystals.

Comment on solubility

Solubility of 2-chloro-4-nitro-benzoic acid

2-chloro-4-nitro-benzoic acid (C7H4ClNO3) is a compound that possesses unique solubility characteristics, influenced by its molecular structure and functional groups. Understanding its solubility is crucial for applications in both organic synthesis and pharmaceuticals.

Solubility Characteristics:

  • Water Solubility: This compound exhibits a low to moderate solubility in water. The presence of the carboxylic acid group (-COOH) does contribute to its potential to dissolve in water, but the bulky chloro and nitro substituents may hinder solubilization.
  • Solvent Compatibility: 2-chloro-4-nitro-benzoic acid is more soluble in organic solvents such as ethanol and acetone. This is attributed to the hydrophobic interactions of the aromatic ring and the electron-withdrawing nature of the nitro and chloro groups.
  • pH Dependency: The solubility can also be affected by the pH of the solution. In acidic conditions, the acid remains largely non-ionized, while in basic conditions, deprotonation can increase its solubility.
  • Temperature Effects: Typically, increasing the temperature enhances solubility for many organic compounds, including this acid, which can be advantageous in extraction and purification processes.

In summary, while 2-chloro-4-nitro-benzoic acid has limited solubility in water, it can be effectively dissolved in various organic solvents. Such insights into its solubility behavior are essential for researchers and practitioners to optimize its use in laboratory and industrial applications.

Interesting facts

Interesting Facts about 2-Chloro-4-Nitro-Benzoic Acid

2-Chloro-4-nitro-benzoic acid, commonly abbreviated as CNBA, is a fascinating compound in the field of organic chemistry. Here are some engaging insights about this compound:

  • Versatile Intermediate: CNBA is often used as an intermediate in organic synthesis, particularly in the production of dyes, pharmaceuticals, and agrochemicals. Its structural features allow it to undergo various chemical transformations.
  • Biological Activity: Research indicates that CNBA exhibits interesting biological properties, making it a useful compound for medicinal chemistry studies. It has been subjected to investigations for its potential antibacterial and anti-inflammatory effects.
  • Role in Chemical Reactions: The presence of both a nitro group and a chloro group in CNBA promotes electrophilic substitution reactions, allowing it to participate in the synthesis of more complex molecules efficiently.
  • Environmental Importance: As a benzoic acid derivative, CNBA is also considered in environmental chemistry for its potential interactions and behavior in various ecosystems, especially when used in agricultural applications.
  • Analytical Applications: CNBA serves as an important compound in the field of analytical chemistry. It can be used as a calibrant or standard for various spectrometric methods, ensuring accurate measurements in research and industrial settings.

In summary, 2-chloro-4-nitro-benzoic acid is not just a simple organic compound; it plays significant roles in diverse fields such as medicinal chemistry, environmental studies, and industrial processes. Its unique properties and reactivity continue to inspire chemical research and development.

Synonyms
2-CHLORO-4-NITROBENZOIC ACID
99-60-5
Benzoic acid, 2-chloro-4-nitro-
NSC 150
MFCD00007209
Kyselina 2-chloro-4-nitrobenzoova
AI3-33426
EINECS 202-771-0
4-nitro-2-chlorobenzoic acid
BRN 1912836
2NCV59M7PS
o-Chloro-p-nitrobenzoic acid
NSC150
DTXSID2059198
NSC-150
4-09-00-01229 (Beilstein Handbook Reference)
2-Chloro-4-nitrobenzoicacid
Kyselina 2-chloro-4-nitrobenzoova [Czech]
2-chloro-4-nitro-benzoic acid
2-Chloro-4-Nitro Benzoic acid
WLN: WNR CG DVQ
UNII-2NCV59M7PS
2-chloro-4-nitro-benzoate
2-chloro4-nitrobenzoic acid
2-chlor-4-nitrobenzoic acid
SCHEMBL231457
4-nitro-2-chloro-benzoic acid
SCHEMBL3024416
CHEMBL4160413
DTXCID5049108
STR03500
BBL009654
STK361845
2-Chloro-4-nitrobenzoic acid, 98%
AKOS000119597
CS-W008613
AC-11452
SY001415
DB-027955
NS00022927
EN300-18336
D87508
AF-407/05487048
Z57915332
F0850-6784
202-771-0