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2-Chloro-4-phenyl-aniline

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Identification
Molecular formula
C12H10ClN
CAS number
5468-37-1
IUPAC name
2-chloro-4-phenyl-aniline
State
State

At room temperature, 2-Chloro-4-phenyl-aniline is typically found as a solid. It is generally handled and transported in solid form.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
203.67g/mol
Molar mass
203.6650g/mol
Density
1.2370g/cm3
Appearence

2-Chloro-4-phenyl-aniline appears as a pale yellow to brown crystalline solid. It may also appear as a powder with varying shades based on purity and specific conditions.

Comment on solubility

Solubility of 2-chloro-4-phenyl-aniline

The solubility of 2-chloro-4-phenyl-aniline can be quite intriguing due to its chemical structure. This compound is known to be sparingly soluble in water, which can be attributed to the presence of both an amino group and a chlorine atom. Understanding its solubility can be broken down into a few key points:

  • Polarity: The amino group (-NH2) tends to increase solubility in polar solvents, while the chlorine atom can introduce more complex interactions.
  • Hydrogen Bonding: The ability of the amino group to form hydrogen bonds with water molecules enhances solubility, but the overall interaction may still be limited.
  • Organic Solvents: 2-chloro-4-phenyl-aniline is generally more soluble in organic solvents such as ethanol, acetone, or chloroform where non-polar interactions can dominate.

In summary, the solubility of 2-chloro-4-phenyl-aniline varies significantly based on the solvent used. While it exhibits low solubility in water, its compatibility with organic solvents reflects its hydrophobic characteristics. As noted, increases in temperature may also facilitate better solubility in certain solvents, illustrating the dynamic nature of solubility.

Interesting facts

Interesting Facts about 2-chloro-4-phenyl-aniline

2-chloro-4-phenyl-aniline, also known as a versatile chemical compound, holds significant importance in both industrial applications and scientific research. Here are some fascinating insights:

  • Structure and Composition: This compound is part of the aniline family, featuring an amino group attached to a phenyl ring. The presence of a chlorine atom in the para position to the amino group enhances its reactivity, making it a useful intermediate in organic synthesis.
  • Applications in Dyes: 2-chloro-4-phenyl-aniline is commonly employed as a precursor in the manufacturing of various dyes and pigments, particularly in the textile industry, due to its ability to form vibrant colors.
  • Pharmaceutical Relevance: The compound often serves as a building block in the synthesis of pharmaceuticals. Its derivatives can exhibit biological activity, leading to the discovery of new therapeutic agents.
  • Environmental Concerns: As with many chlorinated compounds, the environmental impact should not be overlooked. Its potential effects and persistence in the environment make it a topic of study for environmental chemists.
  • Safety Precautions: When handling this compound, it is crucial to observe safety measures. As it can be harmful if inhaled or absorbed through the skin, proper protective equipment should always be used.

In conclusion, 2-chloro-4-phenyl-aniline is more than just a chemical formula; it represents a crucial component in various chemical processes, with implications ranging from industrial applications to safety and environmental considerations. As researchers continue to explore its properties and potential uses, the significance of this compound within the field of chemistry remains ever-growing.

Synonyms
3-Chloro-biphenyl-4-ylamine
7285-66-7
2-chloro-4-phenylaniline
3-chlorobiphenyl-4-amine
3-Chloro-[1,1'-biphenyl]-4-amine
4-BIPHENYLAMINE, 3-CHLORO-
3-Chlorobiphenylamine
3-Chloro-4-aminodiphenyl
BRN 2803530
MFCD01740412
CHEMBL443531
SCHEMBL7142676
DTXSID50205922
AKOS000124887
DB-151535
CS-0194620
EN300-57811
E89597