Skip to main content

Chlordiazepoxide

ADVERTISEMENT
Identification
Molecular formula
C16H14ClN3O
CAS number
58-25-3
IUPAC name
2-chloro-5-[3-(dimethylamino)propyl]-11H-benzo[b][1,4]benzodiazepin-6-one
State
State

At room temperature, Chlordiazepoxide is a solid. It is stable under normal conditions and used in various pharmaceutical applications, primarily as a medication for treating anxiety disorders.

Melting point (Celsius)
231.00
Melting point (Kelvin)
504.15
Boiling point (Celsius)
729.15
Boiling point (Kelvin)
1 002.30
General information
Molecular weight
299.76g/mol
Molar mass
299.7700g/mol
Density
1.3960g/cm3
Appearence

Chlordiazepoxide typically appears as a white or yellow crystalline powder. It is odorless and has a bitter taste. The compound is often used in its hydrochloride form, which shares similar physical characteristics.

Comment on solubility

Solubility of 2-chloro-5-[3-(dimethylamino)propyl]-11H-benzo[b][1,4]benzodiazepin-6-one

The solubility of 2-chloro-5-[3-(dimethylamino)propyl]-11H-benzo[b][1,4]benzodiazepin-6-one is influenced by several factors, primarily its chemical structure and molecular interactions. Understanding its solubility is crucial, especially in pharmacological contexts, where bioavailability is a significant concern. Here are some key points to consider:

  • Polarity: The presence of functional groups, such as the dimethylamino group, can enhance solubility in polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvents can greatly affect the compound's solubility.
  • Solvent Type: While organic solvents may provide better solubility for this compound, aqueous solubility could be limited.

As noted in research, "the solubility profile of a compound is often a reflection of its structural characteristics." Therefore, solubility assessments should involve various solvents to identify the most suitable conditions for dissolution. Factors such as temperature and pH can also play significant roles in the compound’s solubility.

In conclusion, while 2-chloro-5-[3-(dimethylamino)propyl]-11H-benzo[b][1,4]benzodiazepin-6-one shows potential for solubility in certain conditions, it necessitates thorough investigation to fully ascertain its behavior in different environments.

Interesting facts

Interesting Facts About 2-chloro-5-[3-(dimethylamino)propyl]-11H-benzo[b][1,4]benzodiazepin-6-one

2-chloro-5-[3-(dimethylamino)propyl]-11H-benzo[b][1,4]benzodiazepin-6-one is a distinctive compound with a fascinating profile. This compound is a member of the benzodiazepine class, which is widely known for its significant pharmacological properties.

Key Characteristics:

  • Pharmacological Activity: Compounds in the benzodiazepine class are primarily recognized for their effects on the central nervous system. They often exhibit sedative, anxiolytic, muscle relaxant, and anticonvulsant properties.
  • Structural Complexity: The unique structure combines a benzo[b][1,4]benzodiazepine core with additional moieties, allowing for diverse interactions within biological systems. This complexity often leads to varied activities depending on the substitutions present.
  • Research Applications: Researchers have explored the potential of compounds like this one in treating anxiety, sleep disorders, and other CNS-related conditions, showing promise in clinical settings.

As noted by experts in the field, "the modifications in the substituents can significantly impact the pharmacological profile of benzodiazepines, leading to a range of therapeutic options." This emphasizes the importance of studying structural variations.

Potential Implications:

  • Dose-Dependent Effects: The efficacy and safety of benzodiazepines often depend on their dosage, similar principles apply to 2-chloro-5-[3-(dimethylamino)propyl]-11H-benzo[b][1,4]benzodiazepin-6-one.
  • Side Effects: While they are therapeutic, benzodiazepines can also lead to side effects, including dependence and withdrawal symptoms, making responsible use crucial.
  • Future Research: Ongoing studies aim to reduce negative side effects while enhancing beneficial actions, thereby improving patient outcomes in using benzodiazepines.

In conclusion, 2-chloro-5-[3-(dimethylamino)propyl]-11H-benzo[b][1,4]benzodiazepin-6-one represents a compound with the potential for significant therapeutic applications and a rich field for research exploration. As the scientific community continues to investigate its properties, we can anticipate valuable insights that may enhance our understanding and treatment of various health conditions.

Synonyms
1163-09-3
5H-Dibenzo(b,e)(1,4)diazepin-11-one, 10,11-dihydro-7-chloro-10-(3-(dimethylamino)propyl)-
DTXSID50151339
10,11-Dihydro-11-oxo-5H-dibenzo(b,e)(1,4)diazepine, 7-chloro-10-(3-(dimethylamino)propyl)-
DTXCID9073830