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Olanzapine

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Identification
Molecular formula
C17H20ClN3O
CAS number
132539-06-1
IUPAC name
2-chloro-5-ethyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one
State
State

At room temperature, olanzapine is typically found in a solid state. It manifests as a powder, particularly suitable for tablet formulations used in pharmaceuticals.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
563.20
Boiling point (Kelvin)
836.35
General information
Molecular weight
312.82g/mol
Molar mass
312.4350g/mol
Density
1.2790g/cm3
Appearence

Olanzapine typically appears as a yellow to off-white crystalline powder. It is not crystalline in the traditional sense of large rough crystals; instead, it tends to appear as fine powder particles.

Comment on solubility

Solubility of 2-chloro-5-ethyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one (C17H20ClN3O)

The solubility characteristics of 2-chloro-5-ethyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one can be intricate due to its complex molecular structure. Understanding the solubility of this compound is essential for its practical applications in various fields, particularly in pharmaceuticals. Here are some key points regarding its solubility:

  • Polar vs. Nonpolar Solubility: As a result of the presence of both a chlorine atom and nitrogen atoms, this compound may exhibit moderate solubility in polar solvents such as methanol or ethanol while being less soluble in nonpolar solvents.
  • Influence of Functional Groups: The diverse functional groups within its structure can interact with solvent molecules. This diversity often enhances solubility in specific solvents due to hydrogen bonding or dipole-dipole interactions.
  • Temperature and Solubility: Generally, an increase in temperature can lead to an increase in solubility for many organic compounds. However, this can vary based on the specific compound and solvent combination.

In summary, while 2-chloro-5-ethyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one does possess potential solubility in specific polar solvents, its complete solubility profile can only be accurately determined through empirical testing. As with many chemical compounds, solubility can greatly affect both its reactivity and bioavailability, making it a critical parameter for research and application.

Interesting facts

Interesting Facts about 2-chloro-5-ethyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one

The compound 2-chloro-5-ethyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one is a fascinating member of the benzodiazepine family known for its complex structure and potential applications. Here are some important insights:

  • Structural complexity: This compound features a unique bicyclic structure that incorporates both isoquinoline and benzodiazepine components. This combination contributes to its distinct chemical properties.
  • Psychoactive effects: Compounds in the benzodiazepine family are often investigated for their psychoactive effects, including anxiolytic, sedative, and muscle relaxant properties. This particular compound may contribute to ongoing research in these areas.
  • Pharmaceutical potential: With a structure that suggests potential activity on GABA receptors, it could be a candidate for developing new medications aimed at treating anxiety disorders or insomnia.
  • Chirality: The existence of chiral centers in the molecule can lead to enantiomers with different biological activities, making stereochemistry a key factor in pharmacological research.
  • Research interest: Due to its structural rarity, this compound has attracted attention for its role in the field of medicinal chemistry, inspiring the synthesis of derivatives that may enhance drug efficacy and specificity.

As scientists continue to explore the potential of complex compounds like 2-chloro-5-ethyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one, the understanding of their effects and applications may pave the way for innovative therapeutic strategies. The combination of its intricate structure and potential biological effects makes it a noteworthy compound in both academic and pharmaceutical research.

Synonyms
10159-05-4
BRN 0763065
2-Chloro-5-ethyl5,9,10,14b-tetrahydroisoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one
Isoquino(2,1-d)(1,4)benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-2-chloro-5-ethyl-
2-chloro-5-ethyl-7,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one
2-Chloro-5-ethyl-5,9,10,14b-tetrahydroisoquino[2,1-d][1,4]benzodiazepin-6(7H)-one
DTXSID70906383
2-Chloro-5-ethyl-5,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6(7H)-one