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2-Chloro-5-nitrobenzoic acid

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Identification
Molecular formula
C7H4ClNO4
CAS number
2516-96-3
IUPAC name
2-chloro-5-nitro-benzoic acid
State
State

At room temperature, 2-Chloro-5-nitrobenzoic acid is in a solid state.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.00
Boiling point (Celsius)
277.00
Boiling point (Kelvin)
550.00
General information
Molecular weight
201.56g/mol
Molar mass
201.5610g/mol
Density
1.6530g/cm3
Appearence

2-Chloro-5-nitrobenzoic acid is a pale yellow crystalline solid that may appear as a powder or in crystalline form. It is typically used in organic synthesis and might have a slight odor typical of nitro compounds.

Comment on solubility

Solubility of 2-chloro-5-nitro-benzoic acid

2-chloro-5-nitro-benzoic acid, with the formula C7H4ClNO4, exhibits interesting solubility characteristics that are worthy of discussion. The solubility of this compound can be evaluated based on several factors:

  • Solvent Type: This compound is more soluble in polar solvents such as water and alcohol due to the presence of the carboxylic acid group (-COOH), which can form hydrogen bonds.
  • Temperature Influence: As is typical with many organic acids, an increase in temperature generally enhances solubility.
  • pH Dependency: The solubility of 2-chloro-5-nitro-benzoic acid can also be affected by the pH of the solution. In more alkaline solutions, the deprotonation of the carboxylic acid results in an anionic form, which is usually more soluble.

In summary, the solubility of 2-chloro-5-nitro-benzoic acid is notably influenced by its chemical structure and the environmental conditions. It can generally be described as moderately soluble in polar solvents, making it a compound of interest in various chemical applications.

Interesting facts

Interesting Facts About 2-chloro-5-nitro-benzoic acid

2-chloro-5-nitro-benzoic acid is a fascinating compound that has garnered attention in various fields of research and applications. Here are some key facts that highlight its importance:

  • Chemical Structure: The structure of 2-chloro-5-nitro-benzoic acid features both a chlorine and a nitro group on a benzoic acid backbone, making it a unique member of the substituted benzoic acids. These substitutions can greatly influence the compound’s reactivity and physical properties.
  • Applications: This compound is often utilized in organic synthesis, serving as a building block in the production of various pharmaceuticals and agrochemicals. Its functional groups make it particularly valuable for developing compounds with biological activity.
  • Research Utility: Researchers have been exploring 2-chloro-5-nitro-benzoic acid in the context of targeted drug delivery systems and as a potential precursor for synthesizing bioactive molecules. Its nitro group can be reduced to an amine, opening up various synthetic pathways.
  • Investigative Use: The compound has been investigated for its antibacterial properties, with studies focusing on its effectiveness against certain pathogens. This adds to its significance in medicinal chemistry and the search for new therapeutic agents.
  • Environmental Impact: Understanding the environmental behavior of 2-chloro-5-nitro-benzoic acid is crucial as well. Studies on how this compound interacts within ecosystems, particularly its degradation products, help in assessing its environmental risks.

As with **many chemical compounds**, 2-chloro-5-nitro-benzoic acid embodies the interplay between chemistry and practical applications, making it an intriguing subject for both chemists and students alike.

Synonyms
2-CHLORO-5-NITROBENZOIC ACID
Benzoic acid, 2-chloro-5-nitro-
P27EEY2MW8
NSC 8441
NSC-8441
EINECS 219-739-7
UNII-P27EEY2MW8
AI3-16578
DTXSID9062485
EC 219-739-7
2-CHLORO,5-NITRO-BENZOIC ACID
MESALAZINE IMPURITY M [EP IMPURITY]
MESALAZINE IMPURITY M (EP IMPURITY)
6Chloro3nitrobenzoic acid
Benzoic acid, 2chloro5nitro
DTXCID5037232
inchi=1/c7h4clno4/c8-6-2-1-4(9(12)13)3-5(6)7(10)11/h1-3h,(h,10,11
quekgyqtrjveqc-uhfffaoysa-n
2516-96-3
2-Chloro-5-nitrobenzoicacid
6-Chloro-3-nitrobenzoic acid
5-nitro-2-chlorobenzoic acid
2-chloro-5-nitro-benzoic acid
MFCD00007294
2-Chloro-5-nitrobenzoic Acid; Mesalazine Imp. M (EP); Mesalazine Impurity M
NSC8441
2-chloro-5-nitrobenzic acid
SCHEMBL231222
2-Chloro-5-nitro benzoic acid
2-chloro-5-nitrobenzoyl alcohol
CHEMBL2179897
BBL008923
STK498300
2-Chloro-5-nitrobenzoic acid, 97%
AKOS000119020
AC-2641
FC70531
VS-02007
DB-014082
CS-0017179
NS00003495
EN300-18335
D70535
AF-407/05487047
Z57914127
F0850-6796
2-Chloro-5-nitrobenzoic acid, Pharmaceutical Secondary Standard; Certified Reference Material