Chlorphenamine | Solubility of Things

Identification

Molecular formula

C₁₈H₂₆ClNO

CAS number

132-22-9

IUPAC name

(2-chloro-6-methyl-phenyl) 2-(diethylamino)acetate

State

Chlorphenamine is typically in a solid crystalline state at room temperature.

Melting point (Celsius)

118.00

Melting point (Kelvin)

391.15

Boiling point (Celsius)

350.00

Boiling point (Kelvin)

623.15

General information

Molecular weight

274.87g/mol

Molar mass

274.7890g/mol

Density

1.0699g/cm³

Appearence

Chlorphenamine is typically a white to off-white crystalline powder. It is often found in pharmaceutical formulations as tablets or solutions due to its therapeutic use.

Comment on solubility

Solubility of (2-chloro-6-methyl-phenyl) 2-(diethylamino)acetate

The solubility of (2-chloro-6-methyl-phenyl) 2-(diethylamino)acetate can exhibit varied characteristics depending on the solvent used. Here are some key considerations:

Polar Solvents: This compound tends to show increased solubility in polar solvents, such as water and alcohols, due to the presence of the diethylamino group, which can engage in hydrogen bonding.
Non-Polar Solvents: Conversely, in non-polar solvents like hexane, the solubility can be significantly lower owing to the hydrophobic nature of the aromatic ring.
Temperature Effects: Solubility may also be influenced by temperature; generally, an increase in temperature can enhance solubility in various solvents.
pH Dependence: The solubility may also be pH-dependent, as the diethylamino group can be protonated in acidic conditions, affecting overall solubility.

In summary, the solubility of (2-chloro-6-methyl-phenyl) 2-(diethylamino)acetate is influenced by a range of factors including the choice of solvent, temperature, and pH conditions. As a result, it is important to consider these aspects when predicting or measuring solubility for practical applications.

Interesting facts

Interesting Facts About (2-chloro-6-methyl-phenyl) 2-(diethylamino)acetate

(2-chloro-6-methyl-phenyl) 2-(diethylamino)acetate is a fascinating chemical compound that combines elements of organic chemistry with valuable applications in various fields. Here are some intriguing aspects of this compound:

Structure: The compound features a chlorinated aromatic ring, which is known for enhancing biological activity due to the electronegative chlorine atom. This substitution can influence reaction pathways and the compound's overall reactivity.
Applications: Due to its structure, this compound is often studied for its potential use in the pharmaceutical industry. It serves as an intermediate in the synthesis of drugs or even as a precursor in the development of novel therapeutic agents.
Biological Activity: Compounds that share similar structural motifs with (2-chloro-6-methyl-phenyl) 2-(diethylamino)acetate often exhibit interesting biological properties, including analgesic, anti-inflammatory, and possibly antihistaminic effects.
Amine Component: The diethylamino group contributes significant basicity, making the compound versatile in chemical reactions and allowing it to engage in hydrogen bonding, which can alter solubility and stability in biological systems.
Research Interest: Scientists often explore the intricacies of such compounds through molecular modeling and simulations, aiming to predict their behavior in complex biological environments and enhance their therapeutic efficacy.

In summary, (2-chloro-6-methyl-phenyl) 2-(diethylamino)acetate is not just a chemical compound; it offers a glimpse into the dynamic world of medicinal chemistry and underscores the importance of understanding molecular interactions in developing effective treatments. As the field expands, continuous research may unlock further applications and insights into this intriguing compound.