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2-Chloro-6-(trichloromethyl)pyridine

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Identification
Molecular formula
C6H3Cl4N
CAS number
1929-82-4
IUPAC name
2-chloro-6-(trichloromethyl)pyridine
State
State

At room temperature, 2-Chloro-6-(trichloromethyl)pyridine is typically a solid, though it can exist near its melting point as a liquid.

Melting point (Celsius)
31.00
Melting point (Kelvin)
304.15
Boiling point (Celsius)
221.00
Boiling point (Kelvin)
494.15
General information
Molecular weight
228.90g/mol
Molar mass
228.3930g/mol
Density
1.5734g/cm3
Appearence

2-Chloro-6-(trichloromethyl)pyridine is a colorless to pale yellow crystalline solid. It is known for its distinctive appearance which is typical of many chlorinated aromatic compounds.

Comment on solubility

Solubility of 2-chloro-6-(trichloromethyl)pyridine

When examining the solubility of 2-chloro-6-(trichloromethyl)pyridine, several key factors come into play:

  • Polarity: This compound contains multiple chlorine atoms, which contributes to its polar characteristics. Polar compounds typically have higher solubility in polar solvents.
  • Solvent Interaction: 2-chloro-6-(trichloromethyl)pyridine is known to be soluble in organic solvents such as chloroform and methanol, but it demonstrates limited solubility in water due to the significant hydrophobic nature of the trichloromethyl group.
  • Temperature Effects: Solubility can vary with temperature. Generally, increased temperature leads to greater solubility for many compounds, thus impacting 2-chloro-6-(trichloromethyl)pyridine as well.
  • Hydrogen Bonding: The presence of nitrogen in the pyridine ring can enable some degree of hydrogen bonding with suitable solvents, thereby affecting solubility in non-polar environments.

In summary, while 2-chloro-6-(trichloromethyl)pyridine is soluble in several organic solvents, it should be noted that its solubility is limited in aqueous environments primarily due to its hydrophobic components. As stated, "like dissolves like," emphasizing the importance of matching polarities when considering solubility.

Interesting facts

Interesting Facts About 2-Chloro-6-(Trichloromethyl)pyridine

2-Chloro-6-(trichloromethyl)pyridine is a fascinating compound with a rich history and significant applications in various fields. Here are some intriguing facts:

  • Active Intermediate: This compound is often used as an active intermediate in the synthesis of various pharmaceuticals and agrochemicals. It serves as a building block for creating more complex molecules.
  • Unique Structure: The presence of both chlorine and trichloromethyl groups enhances its reactivity. This unique structure makes it particularly valuable in organic synthesis, where selective reactivity is vital.
  • Role in Research: It is also an important subject in research, especially in investigations involving heterocyclic chemistry. Scientists study its properties to understand the behavior of chlorinated pyridines and their derivatives.
  • Environmental Considerations: As a chlorinated compound, it is crucial to understand the environmental implications of its use and disposal. Research on its degradation and potential ecological effects is ongoing.
  • Biological Activity: Compounds related to 2-chloro-6-(trichloromethyl)pyridine have been reported to exhibit various biological activities, making them of interest in the development of new agrochemicals and medicinal compounds.

In summary, 2-chloro-6-(trichloromethyl)pyridine is more than just a chemical compound; it is a key player in synthetic chemistry, offering numerous opportunities for innovation and research.

Synonyms
NITRAPYRIN
1929-82-4
N-Serve
2-chloro-6-trichloromethylpyridine
Pyridine, 2-chloro-6-(trichloromethyl)-
Caswell No. 217
Nitrapyrin [ISO]
Nitrapyrine [ISO-French]
Nitrapyrin [ANSI:BSI:ISO]
CCRIS 4599
2-Chloro-6-trichloromethyl pyridine
EINECS 217-682-2
UNII-8PCE86U01W
EPA Pesticide Chemical Code 069203
BRN 1618997
8PCE86U01W
DTXSID0024216
CHEBI:81935
NITRAPYRIN [MI]
DTXCID504216
EC 217-682-2
5-20-05-00500 (Beilstein Handbook Reference)
Nitrapyrine (ISO-French)
Nitrapyrin (ANSI:BSI:ISO)
2-Picoline, .alpha.,.alpha.,.alpha.,6-tetrachloro-
NServe
2,2,2,6-Tetrachloro-2-picoline
6-chloro-2-(trichloromethyl)pyridine
2-chloro-6-(trichloro-methyl)pyridine
Dowco163
Nitrapyrin (ACGIH)
alpha,alpha,alpha-6-tetrachloro-2-picoline
NServe nitrogen stabilizer
2-Picoline, alpha,alpha,alpha,6-tetrachloro-
N-SERVE 24E
2Chloro6trichloromethyl pyridine
a,a,a,6-Tetrachloro-2-picoline
2Chloro6(trichloromethyl)pyridine
2-TRICHLOROMETHYL-6-CHLOROPYRIDINE
dcujjwwunkijph-uhfffaoysa-n
un2811
2-Chloro-6-(trichloromethyl)pyridine
Dowco-163
N-Serve nitrogen stabilizer
alpha,alpha,alpha,6-tetrachloro-2-picoline
Nitrapyrine
CAS-1929-82-4
SCHEMBL41442
MLS002152872
CHEMBL1557091
2-chloro-6-trichloromethylpyridin
2-chloro-6(trichloromethyl)pyridine
6-chloro-2-trichloromethyl pyridine
Tox21_202036
Tox21_300916
STK843145
2 -chloro-6-(trichloromethyl)pyridine
AKOS000267961
CS-W019363
FC55179
NCGC00091152-01
NCGC00091152-02
NCGC00091152-03
NCGC00091152-04
NCGC00091152-05
NCGC00254819-01
NCGC00259585-01
AC-23339
AS-15459
SMR000777845
DB-240099
NS00005534
EN300-93027
Nitrapyrin, PESTANAL(R), analytical standard
2-Chloro-6-(trichloromethyl)pyridine, >=98%
A10854
C18751
Q1993935
Z56756147