Interesting facts
Interesting Facts about 2-chloro-N-(1-methylprop-2-ynyl)-N-phenyl-acetamide
2-chloro-N-(1-methylprop-2-ynyl)-N-phenyl-acetamide is a fascinating compound that falls under the category of amides. This compound is particularly intriguing due to its structural complexity and potential applications in various fields. Here are some key points to consider:
- Pharmaceutical Relevance: Compounds that contain the amide functional group, like this one, are often implicated in drug design. They can exhibit a wide range of biological activities, making them valuable in medicinal chemistry.
- Structural Features: The presence of the 2–chloro substituent introduces unique electronic effects, which can influence the compound's reactivity and solubility.
- Side Chains: The incorporation of the 1-methylprop-2-ynyl group brings unsaturation and a degree of steric hindrance, which can play a critical role in pharmacodynamics and pharmacokinetics.
- Versatile Reactions: The compound can participate in a variety of chemical reactions, such as nucleophilic substitutions, due to its reactive chlorinated site. This makes it a potentially useful intermediate in organic synthesis.
- Research Applications: As researchers explore the potential uses of compounds similar to 2-chloro-N-(1-methylprop-2-ynyl)-N-phenyl-acetamide, they often focus on how modifications to the amide group can enhance biological activities or alter pharmacological profiles.
In summary, 2-chloro-N-(1-methylprop-2-ynyl)-N-phenyl-acetamide is not merely a compound of theoretical interest; it showcases how even small changes in molecular structure can lead to significant variations in chemistry and applications. As emphasized by many chemists, the relationship between structure and functionality is key in the development of new materials and drugs.
Synonyms
Prynachlor
21267-72-1
Basamaize
Butisan
Butisane
Chloretin
Prynachlore
BAS 2903H
Caswell No. 714BB
BAS 2900H
1N7ETM5RG0
Acetanilide, 2-chloro-N-(3-butynyl)-
BAS-290-H
Chloressigsaeure-N-isobutinylanilid
2-Chloro-N-(1-methyl-2-propynyl)acetanilide
EINECS 244-304-3
N-Acetyl-N-3-butinyl-2-chloranilin
Acetanilide, 2-chloro-N-(1-methyl-2-propynyl)-
UNII-1N7ETM5RG0
EPA Pesticide Chemical Code 314300
BRN 2941314
Acetamide, 2-chloro-N-(1-methyl-2-propynyl)-N-phenyl-
BAS 290H
Chloressigsaeure-N-isobutinylanilid [German]
DTXSID7042350
N-Acetyl-N-3-butinyl-2-chloranilin [Czech]
2903 H
2-Chloro-N-(1-methyl-2-propynyl)-N-phenylacetamide
2903-H
CHLOROACETIC ACID N-BUT-1-YN-3-YLANILIDE
N-(1-METHYL-2-PROPYNYL)-.ALPHA.-CHLOROACETANILIDE
ACETAMIDE, 2-CHLORO-N-(1-METHYL-2-PROPYN-1-YL)-N-PHENYL-
RefChem:176774
DTXCID5022350
Acetanilide, 2-chloro-N-(1-methyl-2-propynyl)-(8CI)
N-(1-METHYL-2-PROPYNYL)-ALPHA-CHLOROACETANILIDE
Acetamide, 2-chloro-N-(1-methyl-2-propynyl)-N-phenyl-(9CI)
244-304-3
DGPBHERUGBOSFZ-UHFFFAOYSA-N
N-but-3-yn-2-yl-2-chloro-N-phenylacetamide
SCHEMBL134456
NS00026824
2-chloro-N-(1-methylprop-2-ynyl)-N-phenyl-acetamide
Q27252638
2-Chloro-N-(1-methyl-2-propynyl)-N-phenylacetamide #
Solubility of 2-chloro-N-(1-methylprop-2-ynyl)-N-phenyl-acetamide
The solubility of 2-chloro-N-(1-methylprop-2-ynyl)-N-phenyl-acetamide can be influenced by several factors, including the presence of polar and non-polar functional groups within its structure. Generally, this compound exhibits moderate solubility in organic solvents such as:
However, its solubility is limited in polar solvents such as water due to the hydrophobic characteristics of its phenyl ring and the alkyne moiety. To better understand its solubility properties, consider the following key points:
In summary, while 2-chloro-N-(1-methylprop-2-ynyl)-N-phenyl-acetamide shows some solubility in organic solvents, it is largely insoluble in water, highlighting the importance of chemical structure in determining solubility behavior.