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Chloramphenicol impurity 3

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Identification
Molecular formula
C6H10Cl2N2O2
CAS number
96-09-3
IUPAC name
2-chloro-N-[2-[(2-chloroacetyl)amino]ethyl]acetamide
State
State

Solid at room temperature. Due to its crystalline structure, it maintains a stable form under standard ambient conditions. Typically, it is handled as a powder.

Melting point (Celsius)
108.00
Melting point (Kelvin)
381.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
192.05g/mol
Molar mass
192.0510g/mol
Density
1.3478g/cm3
Appearence

2-Chloro-N-[2-[(2-chloroacetyl)amino]ethyl]acetamide is typically a white crystalline powder. It is a solid under normal conditions, and owing to its crystalline structure, it can appear glossy or shiny. The compound's purity can affect its appearance considerably, with impurities potentially leading to a more powdery, less crystalline form. Handling should be done with care to preserve its integrity.

Comment on solubility

Solubility of 2-chloro-N-[2-[(2-chloroacetyl)amino]ethyl]acetamide

The solubility of 2-chloro-N-[2-[(2-chloroacetyl)amino]ethyl]acetamide can be quite intriguing due to its chemical structure. This compound is expected to exhibit varying solubility characteristics influenced by several factors. Here are some key points to consider:

  • Polarity: The presence of both chlorine atoms and the amide group contributes to the polarity of the molecule, often enhancing solubility in polar solvents like water.
  • Hydrogen Bonding: The amide functional group can participate in hydrogen bonding, which typically facilitates solubility in protic solvents.
  • Chain Length: The ethyl chain may add hydrophobic characteristics, potentially decreasing solubility in highly polar solvents.
  • Temperature Dependence: Like many organic compounds, solubility may increase with temperature, highlighting the importance of environmental conditions.

In conclusion, 2-chloro-N-[2-[(2-chloroacetyl)amino]ethyl]acetamide likely displays moderate solubility in polar solvents, influenced by its structural attributes and external conditions. Understanding these traits is crucial for applications involving this compound, providing insight into its behavior in various solutions.

Interesting facts

Interesting Facts about 2-chloro-N-[2-[(2-chloroacetyl)amino]ethyl]acetamide

This intriguing compound, often referred to in the field of organic chemistry, is notable for its various applications and unique characteristics. As a derivative of acetamide, it incorporates chlorine atoms in its structure, contributing to its chemical reactivity.

Key Features

  • Pharmaceutical Relevance: This compound is studied for its potential role in pharmaceuticals, particularly as an intermediary in the synthesis of various bioactive molecules.
  • Amide Linkages: The amide functional group present in the compound provides unique properties, such as enhanced stability and specific interactions with biological molecules.
  • Chlorine Substitution: The presence of chlorine atoms can influence the compound's ability to react in specific chemical environments, making it a subject of interest for synthetic chemists.

Moreover, it's fascinating to note that compounds like this can exhibit a range of biological activities, including antimicrobial and anti-inflammatory effects. Such activities highlight the importance of structural modifications in medicinal chemistry.

Research and Development

Current research often focuses on the structure-activity relationship (SAR) to optimize the biological activity of similar compounds. Scientists work diligently to uncover the mechanisms through which these compounds exert their effects at the molecular level.

As a compound that bridges the gap between organic synthesis and medicinal chemistry, 2-chloro-N-[2-[(2-chloroacetyl)amino]ethyl]acetamide represents the vital intersection of theoretical exploration and practical application in modern science.

Synonyms
2620-09-9
Bischloroacetylethylinediamine
N, N'-Bis(chloroacetyl)ethylenediamine
ACETAMIDE, N,N'-ETHYLENEBIS(CHLORO-
Acetamide, N,N'-1,2-ethanediylbis[2-chloro-
N,N'-Bis(chloroacetyl)ethylenediamine
N,N'-Ethylene-bis(chloroacetamide)
N,N'-Ethylenebis(2-chloroacetamide)
Acetamide, N,N'-ethylenebis(2-chloro-
4H8KCX7L2G
2-chloro-N-[2-[(2-chloroacetyl)amino]ethyl]acetamide
S 106
Acetamide, N,N'-1,2-ethanediylbis(2-chloro-
N,N'-(Ethane-1,2-diyl)bis(2-chloroacetamide)
N,N'-Ethylenebis(chloroacetamide)
2-chloro-N-[2-(2-chloroacetamido)ethyl]acetamide
NSC-49395
N1-(2-[(2-chloroacetyl)amino]ethyl)-2-chloroacetamide
N1-{2-[(2-chloroacetyl)amino]ethyl}-2-chloroacetamide
N,N'-Ethylenebis[chloroacetamide]
N,N'-1,2-Ethanediylbis[2-chloro-acetamide]; 1,2-Bis(chloroacetamido)ethane; N,N'-Bis(chloroacetyl)-1,2-diaminoethane; NSC 49395;
EINECS 220-054-0
NSC 49395
BRN 1781986
UNII-4H8KCX7L2G
WLN: G1VM2MV1G
SCHEMBL5533465
Acetamide,N'-ethylenebis[chloro-
DTXSID80180834
BQUBHNCENTUVMP-UHFFFAOYSA-N
NSC49395
Acetamide,N'-ethylenebis[2-chloro-
AKOS001043981
N,N'-bis(chloroacetyl)-ethylenediamine
Acetamide,N'-1,2-ethanediylbis[2-chloro-
NS00046289
3-04-00-00523 (Beilstein Handbook Reference)
N,N'-1,2-ETHANEDIYLBIS(2-CHLOROACETAMIDE)
Z56899141
2-CHLORO-N-(2-(2-CHLORO-ACETYLAMINO)-ETHYL)-ACETAMIDE