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Clocortolone

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Identification
Molecular formula
C11H14Cl2N2O
CAS number
2645-32-9
IUPAC name
2-chloro-N-(2-chloroethyl)-N-[3-(2-furyl)prop-2-enylideneamino]ethanamine
State
State

At room temperature, 2-chloro-N-(2-chloroethyl)-N-[3-(2-furyl)prop-2-enylideneamino]ethanamine is typically found in a solid state, often as a crystalline powder.

Melting point (Celsius)
45.00
Melting point (Kelvin)
318.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
299.19g/mol
Molar mass
299.1850g/mol
Density
1.3000g/cm3
Appearence

2-chloro-N-(2-chloroethyl)-N-[3-(2-furyl)prop-2-enylideneamino]ethanamine typically appears as a crystalline solid. The compound may be off-white to light yellow depending on its purity and formation conditions.

Comment on solubility

Solubility of 2-chloro-N-(2-chloroethyl)-N-[3-(2-furyl)prop-2-enylideneamino]ethanamine

The solubility of 2-chloro-N-(2-chloroethyl)-N-[3-(2-furyl)prop-2-enylideneamino]ethanamine is influenced by several factors, including its chemical structure, polarity, and the nature of the solvent. Understanding these aspects can lead to valuable insights:

  • Polarity: This compound contains multiple functional groups that may enhance its ability to interact with polar solvents. However, the presence of chlorine atoms can contribute to reduced solubility in water.
  • Hydrophobic interactions: The furyl group may introduce some hydrophobic characteristics, potentially inhibiting solubility in aqueous environments.
  • Solvent compatibility: It is likely to exhibit better solubility in organic solvents such as dichloromethane or ethyl acetate, where non-polar interactions predominate.

In summary, while this compound may have limited solubility in water due to its structural features, it is expected to be more soluble in non-polar or slightly polar organic solvents. It is always advisable to conduct empirical solubility tests for precise measurements and applications.

Interesting facts

Interesting Facts about 2-chloro-N-(2-chloroethyl)-N-[3-(2-furyl)prop-2-enylideneamino]ethanamine

This compound, known for its unique structural features, belongs to a broader class of compounds that have garnered interest in medicinal chemistry and agricultural applications. Here are some noteworthy points about it:

  • Dual Functionalities: The compound incorporates both a chloro group and a furan ring, which can enhance its reactivity and interactions with biological systems. Compounds with chloro groups are often studied for their ability to participate in nucleophilic substitutions, paving the way for potential applications in drug synthesis.
  • Biological Interest: With its specific arrangement of functional groups, this compound may exhibit novel biological activity. Researchers are intrigued by compounds that can interact with biological targets, and studies may explore its potential as an anticancer agent or as a novel herbicide.
  • Versatile Synthesis: The synthetic pathways leading to compounds like this one often feature interesting reactions, such as condensation and chlorination. Understanding these synthetic routes is crucial for developing more efficient production methods in both academic and industrial settings.
  • Furan Chemistry: The presence of the furan moiety is significant, as compounds containing this five-membered aromatic ring are known for their diverse biological and pharmacological activities. Furan derivatives are commonly studied in the field of organic synthesis and medicinal chemistry.
  • Selectivity and Activity: The combination of the enamine and amine functionalities boosts the potential for selective interactions at the molecular level, which can lead to high specificity in therapeutic applications.

In summary, 2-chloro-N-(2-chloroethyl)-N-[3-(2-furyl)prop-2-enylideneamino]ethanamine not only offers a fascinating glimpse into the intricate world of chemical compounds but also holds promise for various future applications. Its unique structure presents abundant opportunities for researchers in drug development and materials science.