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Chlorambucil

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Identification
Molecular formula
C14H19Cl3N2
CAS number
305-03-3
IUPAC name
2-chloro-N-(2-chloroethyl)-N-[(3-chlorophenyl)methyl]ethanamine
State
State

At room temperature, Chlorambucil is usually in a solid state as a crystalline powder.

Melting point (Celsius)
65.00
Melting point (Kelvin)
338.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
304.68g/mol
Molar mass
304.6840g/mol
Density
1.1000g/cm3
Appearence

Chlorambucil is typically found as a white to light yellow crystalline powder. The compound is solid at room temperature and should be handled with care as it is a chemotherapy drug.

Comment on solubility

Solubility of 2-chloro-N-(2-chloroethyl)-N-[(3-chlorophenyl)methyl]ethanamine

The solubility of 2-chloro-N-(2-chloroethyl)-N-[(3-chlorophenyl)methyl]ethanamine, a compound with a complex structure, exhibits interesting characteristics that can be influenced by various factors:

  • Polarity: The presence of chlorine atoms contributes to the compound's polarity, which may enhance its interaction with polar solvents.
  • Solvent Compatibility: This compound is likely to be soluble in organic solvents such as ethanol or acetone, but may show limited solubility in water due to its hydrophobic components.
  • Temperature Influence: Solubility often increases with temperature; thus, providing heat can enhance the compound's dissolving ability in suitable solvents.
  • pH Levels: Changes in pH can alter the ionization of functional groups, impacting solubility – a critical factor to consider in various chemical scenarios.

In summary, while 2-chloro-N-(2-chloroethyl)-N-[(3-chlorophenyl)methyl]ethanamine demonstrates potential solubility in polar organic solvents, it may exhibit minimal solubility in aqueous environments due to its hydrophobic nature. Understanding these solubility dynamics is crucial for practical applications in chemical processes and formulations.

Interesting facts

Interesting Facts about 2-chloro-N-(2-chloroethyl)-N-[(3-chlorophenyl)methyl]ethanamine

This compound, a fascinating member of the amines family, showcases various applications in both chemical research and medicinal chemistry. Its structure includes multiple chlorinated groups, which often enhance its reactivity and versatility in various chemical processes.

Key Characteristics:

  • Medicinal Potential: The presence of chlorine atoms in the structure can significantly influence the biological activity of the compound. Compounds with similar structural motifs have been evaluated for their roles in antitumor and antimicrobial activities.
  • Functional Diversity: The variety of functional groups present enables potential use in creating diverse pharmaceutical agents or intermediates in organic synthesis.
  • Chlorine Relevance: Chlorine substituents often confer unique electronic properties to the molecule, affecting its interactions with biological targets, making its study particularly relevant in drug discovery.

Applications in Research:

The exploration of this compound opens avenues for research in:

  • Environmental Chemistry: Chlorinated compounds are often scrutinized for their environmental impact and degradation pathways.
  • Material Science: Understanding the stability and reactivity of chlorinated amines contributes to the development of new materials with tailored properties.

As we delve deeper into the properties and potential applications of 2-chloro-N-(2-chloroethyl)-N-[(3-chlorophenyl)methyl]ethanamine, it becomes clear that compounds like this are not just mere substances but rather pivotal elements in advancing our understanding of chemistry and its real-world implications.

Synonyms
m-Chloro-dcba
2361-63-9
N,N-Bis(2-chloroethyl)-m-chlorobenzylamine
2-chloro-N-(2-chloroethyl)-N-[(3-chlorophenyl)methyl]ethanamine
3-Chloro-N,N-bis(2-chloroethyl)benzenemethanamine
Benzenemethanamine, 3-chloro-N,N-bis(2-chloroethyl)- (9CI)
2-Chloro-N-(3-chlorobenzyl)-N-(2-chloroethyl)ethan-1-amine
BRN 2841929
m-Chloro-di-(2-chloroethyl)-benzylamine
Benzenemethanamine, 3-chloro-N,N-bis(2-chloroethyl)-
starbld0003571
BENZYLAMINE, N,N-BIS(2-CHLOROETHYL)-m-CHLORO-
DTXSID80178276
AKOS040752953