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Mechlorethamine N-oxide

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Identification
Molecular formula
C5H12Cl2NO
CAS number
994-84-3
IUPAC name
2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide
State
State

Under normal conditions, this compound is a liquid due to its relatively low melting point. However, it can crystallize if cooled substantially below room temperature.

Melting point (Celsius)
65.00
Melting point (Kelvin)
338.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
154.06g/mol
Molar mass
154.0460g/mol
Density
1.1950g/cm3
Appearence

The compound primarily appears as a colorless to pale yellow, oily liquid. It has a pungent odor that is typical of amine oxides.

Comment on solubility

Solubility of 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide

The solubility of 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide can be characterized by several important factors:

  • Polarity: As an amine oxide, this compound is likely to have significant polar characteristics due to the presence of both amino and ether functionalities.
  • Solvent Interaction: This substance generally exhibits higher solubility in polar solvents such as water, due to hydrogen bonding capabilities. It may also dissolve in organic solvents like ethanol or methanol to a certain extent.
  • Temperature Influence: Solubility may increase with temperature, which is a common behavior observed in many chemical compounds.
  • Concentration Effects: The solubility might also be influenced by the concentration of the compound in the solvent, potentially leading to saturation at higher concentration levels.

Overall, the compound's amphiphilic nature implies that it may dissolve well in both polar and non-polar environments to various extents. As always, it's critical to conduct experimental assessments to determine precise solubility values under defined conditions.

Interesting facts

Interesting Facts about 2-Chloro-N-(2-chloroethyl)-N-methyl-ethanamine Oxide

This compound, known as 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide, presents a fascinating array of characteristics and applications that are significant in the field of chemistry. Here are some compelling points to consider:

  • Chemical Family: This compound belongs to the class of amines, which are nitrogen-containing organic compounds. Amines are known for their diverse applications, ranging from pharmaceuticals to agrochemicals.
  • Chlorinated Structure: The presence of chlorine atoms in its structure enhances its reactivity. Chlorinated compounds often exhibit important characteristics that can be harnessed in various chemical reactions and processes.
  • Oxidation State: The oxidation state of the nitrogen atom in this compound, which is present in the form of an amine oxide, contributes to its unique chemical behavior, including increased stability and potential applications in synthesis.
  • Applications: Compounds of this nature may find utility in medicinal chemistry, particularly in the development of pharmaceuticals. The functional groups present can lead to significant biological activity.
  • Biological Interaction: While the specific biological effects of this compound require further investigation, amine oxides are generally known for their role in mediating biological interactions, making them potential candidates for drug development.

As a compound that exemplifies the complexity and versatility of organic chemistry, 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine oxide reminds us of the continuous exploration within the scientific community. Whether in research labs or industrial applications, compounds like this one play an essential role in advancing our understanding and utilization of chemicals.

Synonyms
Nitrogen mustard N-oxide
126-85-2
Mechlorethamine oxide
HN2 amine oxide
HN2 oxide mustard
Oxy-NH2
N-Oxyd-lost [German]
N-Oxyd-mustard
N-Oxyd-mustard [German]
Nitrogen mustard amine oxide
Methyl-dichlorethylamine oxide
CCRIS 449
2-chloro-N-(2-chloroethyl)-N-methylethanamine oxide
N-Oxyd-Lost
UNII-2Q86QAR1PN
Nitrogen mustard (HN-2), N-oxide
2Q86QAR1PN
Methyl-bis(beta-chloroethyl)amine oxide
BRN 1754386
N-Methyl-di-2-chloroethylamine-N-oxide
DTXSID7020976
2,2'-Dichloro-N-methyldiethylamine-N-oxide
Diethylamine, 2,2'-dichloro-N-methyl-, oxide
Diethylamine, 2,2'-dichloro-N-methyl-, N-oxide
2-Chloro-N-(2-chloroethyl)-N-methylethanamine-N-oxide
DTXCID10976
CHEBI:82354
MECHLORETHAMINE OXIDE [MI]
NSC-141949
NITROGEN MUSTARD N-OXIDE [IARC]
Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-, N-oxide
NITROGEN MUSTARD N-OXIDE (IARC)
Methylbis(beta-chloroethyl)amine N-oxide
bis(2-chloroethyl)methylamine oxide
SCHEMBL24960
CHEMBL502759
AFLXUQUGROGEFA-UHFFFAOYSA-N
Tox21_113709
Methylbis(2-chloroethyl)amine N-oxide
methyl-bis(2-chloroethyl)-amine N-oxide
NCGC00249933-01
CAS-126-85-2
C19274
METHYLBIS(.BETA.-CHLOROETHYL)AMINE N-OXIDE
Q27155895
2-Chloro-N-(2-chloroethyl)-N-methylethan-1-amine oxide
ETHANAMINE, 2-CHLORO-N-(2-CHLOROETHYL)-N-METHYL-,N-OXIDE