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Mechlorethamine hydrochloride

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Identification
Molecular formula
C5H12Cl3N
CAS number
55-86-7
IUPAC name
2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine;hydrochloride
State
State
At room temperature, mechlorethamine hydrochloride is found in a solid state. It is typically stored in airtight containers to avoid moisture absorption due to its hygroscopic nature.
Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
192.53g/mol
Molar mass
156.0380g/mol
Density
1.3510g/cm3
Appearence

Mechlorethamine hydrochloride appears as a white crystalline solid. It can absorb moisture from the air, and thus is hygroscopic. Its solid form is quite stable when dry, but it should be handled carefully due to its potential to cause burns.

Comment on solubility

Solubility of 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine; hydrochloride

The compound 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine; hydrochloride, with the chemical formula C5H12Cl3N, exhibits interesting solubility properties that are essential for its applications.

In general, hydrochloride salts like this compound tend to have the following solubility characteristics:

  • Highly soluble in water: Hydrochloride salts usually dissolve well in aqueous solutions due to the ionic nature of the compound.
  • Dissolution in polar solvents: Solubility is enhanced in polar solvents, as the polar molecules can stabilize the dissolved ions.
  • Limited solubility in non-polar solvents: Compounds of this type often have low solubility in organic solvents that are not polar, due to a lack of solvation possibilities.

In practical applications, the solubility of 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine; hydrochloride is crucial for its effectiveness as a reagent or in pharmacological uses. As stated, it is important to assess the specific conditions, such as temperature and pH, that could influence its solubility:

  • Temperature: Increasing temperature often enhances solubility.
  • pH of the solution: The solubility may vary with pH, especially for amines and salts.

Understanding these aspects of solubility can greatly influence its formulation and use in chemical and pharmaceutical processes.

Interesting facts

Interesting Facts about 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine; hydrochloride

This compound, often referred to as Hydrochloride Salt of 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine, is a fascinating and significant entity in the field of chemistry, particularly in the realm of pharmacology. Here are some engaging insights about this compound:

  • Pharmaceutical Relevance: It is commonly studied for its potential in medicinal applications. The structural modifications present enhance its usability in developing new pharmaceuticals.
  • Mechanism of Action: The presence of chlorine in its structure suggests potential interactions with biological systems, possibly acting on neurotransmitter pathways.
  • Research Applications: It has gained attention in various research studies for evaluating its effectiveness against certain types of bacteria, showcasing antibacterial properties.
  • Synthesis: The synthesis of this compound entails interesting organic reactions, making it a great example for students learning about substitution reactions and amine chemistry.
  • Safety Considerations: Despite its promising applications, the toxicity and safety profile of such nitrogen-containing compounds must be carefully evaluated due to the presence of chlorinated groups.

As a versatile compound, its study encourages a deeper understanding of chemical properties, synthesis, and biological interactions. It stands as a pertinent example of how chemistry can influence both medicinal development and industrial applications.

Quote to Ponder

"The best way to predict the future of pharmacy is to invent it." - Anonymous

This quote emphasizes the continuous innovation required in fields that utilize compounds like 2-chloro-N-(2-chloroethyl)-N-methyl-ethanamine; hydrochloride, inspiring many to explore the underlying chemistry that can lead to new discoveries in healthcare.

Synonyms
55-86-7
Mechlorethamine hydrochloride
Chlormethine hydrochloride
Mechlorethamine HCl
Chlorethamine
2-CHLORO-N-(2-CHLOROETHYL)-N-METHYLETHANAMINE HYDROCHLORIDE
Nitrogen mustard hydrochloride
Chlormethinum
HN2 hydrochloride
Stickstofflost
Chloramin
Dichloren
Bis(2-chloroethyl)methylamine hydrochloride
Nitol takeda
Mustine hydrochloride
ChlorMethine HCl
Azotoyperite
Caryolysine
Embikhine
Embiquine
Mitoxine
Dimitan
Erasol
Nitol
Dema
Erasol-Ido
N-Mustard
Mustin hydrochloride
Nitrogranulogen hydrochloride
MBA hydrochloride
Mechlorethamine chloridrate
N-Methylbis(2-chloroethyl)amine hydrochloride
Stickstofflost-ebewe
Bis(2-chloroethyl)-N-methylamine hydrochloride
2,2'-Dichloro-N-methyldiethylamine hydrochloride
CCRIS 448
Dichloren hydrochloride
SK 101
Carolysine
Mebichloramine
Dichloromethyldiethylamine hydrochloride
Embechine
N-Lost
HSDB 7176
NSC-762
1,5-Dichloro-3-methyl-3-azapentane hydrochloride
Di(2-chloroethyl)methylamine hydrochloride
Methyldi(2-chloroethyl)amine hydrochloride
NCI-C56382
Methylbis(2-chloroethyl)amine hydrochloride
UNII-L0MR697HHI
Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-, hydrochloride
Mustine hydrochlor
Chlormethine (hydrochloride)
EINECS 200-246-0
L0MR697HHI
Mustargen (TN)
MFCD00012517
Erasol hydrochloride
Valchlor (TN)
C 6866
Valchlor
N-Methyl-2,2'-dichlorodiethylamine hydrochloride
NSC762
Embichin hydrochloride
Nitrogen mustard (HN-2), hydrochloride
DTXSID8025757
CHEBI:55368
Chloramin hydrochloride
AI3-16195
Methyldi(beta-chloroethyl)amine hydrochloride
N-Methyl-di-2-chloroethylamine hydrochloride
Caryolysine hydrochloride
NSC-762 hydrochloride
Mechlorethamine hydrochloride [USP]
2-Chloro-N-(2-chloroethyl)-N-methylethanamine hydrochlroide
Methyl-bis(beta-chloroethyl)amine hydrochloride
N-Methyl-bis-beta-chlorethylamine hydrochloride
Chlormethini hydrochloridum
N,N-Bis(2-chloroethyl)methylamine hydrochloride
beta,beta'-Dichlorodiethyl-N-methylamine hydrochloride
DTXCID205757
N,N-Bis(2-chloraethyl)methylamin-hydrochlorid
Mechlorethamine hydrochloride (USP)
Nitrogranulogen
Diethylamine, 2,2'-dichloro-N-methyl, hydrochloride
NCGC00091835-01
2-chloro-N-(2-chloroethyl)-N-methylethanamine;hydrochloride
MECHLORETHAMINE HYDROCHLORIDE [MI]
CHLORMETHINE HYDROCHLORIDE [MART.]
Zagreb
Pliva
1329812-14-7
CHLORMETHINE HYDROCHLORIDE [WHO-DD]
CHLORMETHINE HYDROCHLORIDE [WHO-IP]
MECHLORETHAMINE HYDROCHLORIDE [HSDB]
bis-(2-chloroethyl)methylamine hydrochloride
MECHLORETHAMINE HYDROCHLORIDE [VANDF]
Bis(2-chloroethyl)methylamine-d4Hydrochloride
MECHLORETHAMINE HYDROCHLORIDE [USP-RS]
CHLORMETHINI HYDROCHLORIDUM [WHO-IP LATIN]
Kloramin (VAN)
MECHLORETHAMINE HYDROCHLORIDE [ORANGE BOOK]
MECHLORETHAMINE HYDROCHLORIDE [USP MONOGRAPH]
N-LOST (GERMAN)
N-Mustard [German]
DICHLOREN (GERMAN)
CAS-55-86-7
CHLORMETHINE HYDROCHLORIDE (MART.)
MECHLORETHAMINE HYDROCHLORIDE (USP-RS)
MECHLORETHAMINE HYDROCHLORIDE (USP MONOGRAPH)
Embichen
Onco-Cloramin
Mustargen HCl
Chloromethine HCl
Nitol 'takeda'
Prestwick_37
HN 2 Hydrochloride
Nitrogen mustard HCl
MERCHLORETHAMINE
Mustargen hydrochloride
N,N-Bis(2-chloraethyl)methylamin-hydrochlorid [German]
NITOL "TAKEDA
CHLORETHAMINE HCL
chlorethamine hydrochloride
chlorethazine hydrochloride
Chloromethine hydrochloride
Mechorethamine hydrochloride
C5H12Cl3N
SCHEMBL3855
Hydrochloride, Mechlorethamine
MLS003899210
NSC 762 HYDROCHLORIDE
Methylchlorethamine Hydrochloride
CHEMBL1201001
WLN: G2N1&2G &GH
Mechlorethamine hydrochloride, 98%
EDC81214
HY-B1253
Tox21_111170
Tox21_200638
s4252
AKOS015915356
Tox21_111170_1
CCG-264667
CS-5080
bis(2-chloroethyl)methylammonium chloride
NCGC00091835-10
NCGC00258192-01
BP-20221
SMR000059226
SY003678
DB-007290
WR-147650
bis(2-chloroethyl)-methylamine hydrochloride
bis(2-chloroethyl)methyl amine hydrochloride
N,N-bis(chloroethyl)methylamine hydrochloride
NS00076424
SW220100-1
bis (2-chloroethyl)-methylamine hydrochloride
bis (2-chloroethyl)methyl amine hydrochloride
bis-(2-chloroethyl)-methylamine hydrochloride
n-methylbis (2-chloroethyl)amine hydrochloride
bis-(2-chloroethyl)-methyl-amine hydrochloride
D04872
F11444
Methyldi(.beta.-chloroethyl)amine hydrochloride
N-methyl-bis-(2-chloroethyl)amine hydrochloride
N-methylbis(2-chloroethyl)-amine hydrochloride
2,2'-Dichloro-N-methyldiethylamino hydrochloride
bis-(2-Chloro-ethyl)-methyl-amine hydrochloride
Diethylamine,2'-dichloro-N-methyl, hydrochloride
Methylbis(.beta.-chloroethyl)amine hydrochloride
Diethylamine,2'-dichloro-N-methyl-, hydrochloride
Methyl bis(.beta.-chloroethyl)amine, hydrochloride
N-Methylbis(.beta.-chlorethyl)amine hydrochloride
1,5-Dichloro-3-methyl-3-azapentane, hydrochloride
N,N-bis(2-chloroethyl)-N-methylamine hydrochloride
Diethylamine, 2,2'-dichloro-N-methyl-, hydrochloride
N,N-BIS(2-CHLOROETHYL)METHANAMINE HYDROCHLORIDE
N-METHYLBIS-BETA-CHLORETHYLAMINE HYDROCHLORIDE
Q27124263
.beta.,.beta.'-Dichlorodiethyl-N-methylamine hydrochloride
2-chloro-N-(chloroethyl)-N-methylethanamine hydrochloride
2-chloro-N-(2 -chloroethyl)-N-methylethanamine hydrochloride
2-chloro-N-(2-chloroethyl) -N-methylethanamine hydrochloride
ethanamine,2-chloro-N-(2-chloroethyl)-N-methyl Hydrochloride
ETHANAMINE, 2-CHLORO-N-(2-CHLOROETHY)-N-METHYL-, HYDROCHLORIDE