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Piperaquine

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Identification
Molecular formula
C29H32Cl2N4O
IUPAC name
2-chloro-N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]benzamide
State
State

At room temperature, piperaquine is in a solid state. As a crystalline powder, it retains its form easily under standard storage conditions.

Melting point (Celsius)
181.00
Melting point (Kelvin)
454.15
Boiling point (Celsius)
623.15
Boiling point (Kelvin)
896.30
General information
Molecular weight
535.10g/mol
Molar mass
535.0980g/mol
Density
1.1500g/cm3
Appearence

Piperaquine is typically a white to off-white crystalline powder. Its crystalline structure is evident under microscopic examination, reflecting its purity and stable form.

Comment on solubility

Solubility of 2-chloro-N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]benzamide

The solubility of 2-chloro-N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]benzamide can be influenced by various factors, given its complex structure. Typically, when evaluating the solubility of such organic compounds, several aspects should be considered:

  • Polarity: Generally, polar compounds tend to dissolve well in polar solvents, while non-polar compounds are more soluble in non-polar solvents. This chemical contains both polar and non-polar sections, which might lead to varied solubility in different solvents.
  • Temperature: The solubility of organic compounds can increase with temperature. This is particularly relevant during experiments or applications where heating may occur.
  • pH Levels: The ionization state of the compound can change with pH, which can significantly affect its solubility. For instance, in acidic or basic solutions, the solubility characteristics may differ.
  • Presence of Solvents: Solvents such as ethanol or DMSO (dimethyl sulfoxide) may enhance the solubility of this compound due to their ability to interact with both polar and non-polar sections of the molecule.

As stated, "the solubility characteristics can offer insights into the compound's behavior in biological and chemical systems." Understanding these factors is **crucial** for researchers and practitioners working with 2-chloro-N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]benzamide, especially in formulations, drug delivery systems, or synthesis reactions.

Interesting facts

Interesting Facts about 2-chloro-N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]benzamide

This compound is a fascinating member of the benzamide family, often studied for its potential applications in various fields, particularly in medicinal chemistry. Here are some intriguing aspects to consider:

  • Structural Complexity: The compound features a unique structure characterized by a chlorinated aromatic system and a complex piperidyl moiety, contributing to its high biological activity.
  • Pharmacological Interest: Compounds like this one are often evaluated for their potential as therapeutic agents, particularly in the treatment of disorders involving neurotransmitters.
  • Chirality: The presence of a piperidyl group introduces chirality into the structure, which can lead to different biological activities of the enantiomers.
  • Mechanism of Action: While specific mechanisms can vary, many benzamides have been shown to interact with neurotransmitter receptors, influencing mood and cognition.
  • Research Potential: Ongoing studies aim to explore its effects, which could lead to new insights in the field of psychiatric and neurological disorders.
  • Synthetic Challenges: The synthesis of such complicated structures often requires meticulous planning and execution, showcasing the ingenuity of synthetic chemists.

In conclusion, 2-chloro-N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]benzamide exemplifies the blend of complexity and utility in modern chemistry. As research continues, this compound may reveal further secrets that could enhance our understanding of medicinal compounds.