Skip to main content

Loperamide hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C29H34Cl2N2O
CAS number
34552-83-5
IUPAC name
2-chloro-N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)benzamide;chloride
State
State

At room temperature, Loperamide hydrochloride is a solid.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
513.52g/mol
Molar mass
513.5220g/mol
Density
1.1000g/cm3
Appearence

Loperamide hydrochloride appears as a white or off-white powder. It is odorless and crystalline in nature.

Comment on solubility

Solubility of 2-chloro-N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)benzamide;chloride

The solubility profile of 2-chloro-N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)benzamide;chloride can be quite intriguing due to its complex structure. Here are some key points regarding its solubility:

  • Polarity: The presence of both hydrophilic (polar) and hydrophobic (nonpolar) regions in the molecule suggests that its solubility could be influenced by the polarity of the solvent used.
  • Solvent Compatibility: This compound may exhibit good solubility in polar solvents such as water and alcohols, while potentially having lower solubility in nonpolar solvents like hydrocarbons.
  • Functional Groups: The presence of chlorides and amide functional groups typically enhances solubility in polar media but can complicate interactions in nonpolar environments.
  • Temperature Effects: As with many compounds, increasing temperature may improve solubility, making it essential to consider experimental conditions.

In summary, the solubility of 2-chloro-N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)benzamide;chloride can vary significantly based on the solvent environment and temperature, highlighting the intricate balance of molecular interactions that govern solubility.
Understanding these factors is key for practical applications in pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 2-chloro-N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)benzamide; chloride

This compound is a striking example of a complex organic molecule that blends multiple functional groups with distinctive chemical properties. Here are some intriguing aspects to note:

  • Molecular Complexity: The structure contains a piperidine ring, indicating it may exhibit significant biological activity, commonly associated with compounds that can interact with neurotransmitter receptors.
  • Chirality: Given its multi-ring structure, this compound may have several stereocenters, leading to a variety of stereoisomers. The stereochemistry can play a critical role in its pharmacological activity.
  • Applications: Compounds similar to this one are often investigated for their potential use in medicinal chemistry, particularly in the development of pharmaceuticals that act on the central nervous system.
  • Halogenation: The presence of the chlorine atom may enhance reactivity, making the compound a valuable intermediate in synthetic organic chemistry.
  • Structure-Activity Relationship (SAR): The benzamide group combined with the chlorinated component suggests a possible interest in examining how structural modifications affect biological activity.

As with many chemical compounds, understanding the structure and properties can help in exploring its potential uses and effects. Detailed studies of such molecules not only deepen scientific understanding but also pave the way for new discoveries in drug design and therapeutic applications.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This perfectly encapsulates the journey through organic chemistry, where each compound may lead to multiple exciting pathways in research and application.

Synonyms
Benzamide, o-chloro-N-(alpha-(1-methyl-1-piperidinoethyl)benzilidene)-, monohydrochloride
16297-39-5
2-Chloro-N-(alpha-(1-methyl-1-piperidinoethyl)benzilidene)benzamide monohydrochloride