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2-chloro-N-[3-[(2-chloroacetyl)amino]propyl]acetamide

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Identification
Molecular formula
C7H13Cl2N1O2
CAS number
1207-97-2
IUPAC name
2-chloro-N-[3-[(2-chloroacetyl)amino]propyl]acetamide
State
State

At room temperature, 2-Chloro-N-[3-[(2-chloroacetyl)amino]propyl]acetamide exists as a crystalline solid. Due to its stable structure, it maintains a solid state under standard laboratory conditions, requiring heating or a solvent to transition to a liquid form.

Melting point (Celsius)
113.70
Melting point (Kelvin)
386.85
Boiling point (Celsius)
433.60
Boiling point (Kelvin)
706.75
General information
Molecular weight
211.07g/mol
Molar mass
211.0670g/mol
Density
1.3586g/cm3
Appearence

2-Chloro-N-[3-[(2-chloroacetyl)amino]propyl]acetamide is typically a solid compound, characterized by its off-white to pale yellow coloration, which may vary slightly depending on its specific level of purity and the presence of impurities or additives. It is crystalline in nature, allowing it to be purified through recrystallization techniques.

Comment on solubility

Solubility of 2-chloro-N-[3-[(2-chloroacetyl)amino]propyl]acetamide

The solubility of the compound 2-chloro-N-[3-[(2-chloroacetyl)amino]propyl]acetamide can be influenced by several factors, including polarity, molecular structure, and temperature. This compound features an amide functional group that generally enhances its solubility in polar solvents, particularly water. The following factors can be noted:

  • Polarity: The presence of chlorine atoms and the acetamide group contributes to a moderately polar character, which aids in solubility in polar solvents.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the amide group enhances solubility in water, as water itself is a highly polar solvent.
  • Chain Length: The length of the carbon chain and branching can affect solubility; shorter chains typically allow for better solvation.
  • Temperature:\ Increased temperature often promotes solubility, although this effect can vary based on other interacting substances.

In practice, solubility might be assessed in various solvents such as:

  1. Water - Likely to be a primary solvent due to the polar nature of the compound.
  2. Alcohols - Such as ethanol and methanol that can also enhance solubility through hydrogen bonding.
  3. Organic solvents - While less favorable, some non-polar solvents may dissolve the compound to a limited extent.

In conclusion, while this compound shows potential for solubility in polar environments, the specific conditions will ultimately dictate its solubility behavior. Scientists should utilize relevant analyses to determine actual solubility values for practical applications.

Interesting facts

Interesting Facts About 2-chloro-N-[3-[(2-chloroacetyl)amino]propyl]acetamide

2-chloro-N-[3-[(2-chloroacetyl)amino]propyl]acetamide is a fascinating compound that belongs to the family of acetamides. Here are several points that highlight its significance and fascinating aspects:

  • Biological Activity: This compound exhibits potential biological activities, making it of interest in pharmaceutical research. Compounds containing acetamide structures often show various pharmacological effects.
  • Chlorine Atoms: The presence of chlorine atoms in the molecular structure can enhance the compound's lipophilicity, influencing its ability to cross biological membranes. This property is crucial for drug design and development.
  • Amide Bond: The amide functional group in this compound plays a critical role in stability and reactivity, often making it a target for modifications to improve its efficacy in biological systems.
  • Applications: Due to its unique structure, this compound may find applications in agrochemicals, specifically as a herbicide or fungicide, illustrating the versatility of amides in various fields.
  • Research Potential: Ongoing research is likely to uncover more about this compound's properties, leading to new discoveries in medicinal chemistry and its applications in combating diseases.

As a potential candidate for further investigation, 2-chloro-N-[3-[(2-chloroacetyl)amino]propyl]acetamide embodies the challenges and excitement of chemical research. Its structure and potential applications offer many avenues for exploration, making it an intriguing topic for chemists and students alike.

Synonyms
22358-18-5
ACETAMIDE, N,N'-TRIMETHYLENEBIS(CHLORO-
N,N'-Bis(chloroacetyl)-1,3-propanediamine
1,3-Di-N,N'-chloroacetylaminopropane
S 105
2-chloro-N-[3-[(2-chloroacetyl)amino]propyl]acetamide
N,N'-Trimethylene-bis(chloroacetamide)
N,N'-(Propane-1,3-diyl)bis(2-chloroacetamide)
Acetamide, N,N'-trimethylenebis(2-chloro-
Acetamide, N,N'-1,3-propanediylbis(2-chloro-
DTXSID60176891
MFCD01671275
NSC-58820
NSC 58820
BRN 1785927
GGJ37PH3LJ
RefChem:1090247
1,3-bischloroacetamidopropane
1,N'-chloroacetylaminopropane
3-04-00-00560 (Beilstein Handbook Reference)
SCHEMBL5830059
DTXCID8099382
NSC58820
AKOS003876339
Acetamide,N'-trimethylenebis[2-chloro-
Acetamide,N'-1,3-propanediylbis[2-chloro-
N,N'-1,3-Propanediylbis(2-chloroacetamide)
S-105
F79877