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2-chloro-N-(3-ethoxyphenyl)acetamide

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Identification
Molecular formula
C10H12ClNO2
CAS number
120-32-1
IUPAC name
2-chloro-N-(3-ethoxyphenyl)acetamide
State
State

At room temperature, 2-chloro-N-(3-ethoxyphenyl)acetamide is typically found in a solid state. The crystalline nature of the compound is due to intramolecular interactions facilitated by its aromatic and amide groups.

Melting point (Celsius)
89.00
Melting point (Kelvin)
362.15
Boiling point (Celsius)
297.00
Boiling point (Kelvin)
570.15
General information
Molecular weight
213.65g/mol
Molar mass
213.6530g/mol
Density
1.2672g/cm3
Appearence

The compound 2-chloro-N-(3-ethoxyphenyl)acetamide typically appears as a white solid. The compound's structure features a chlorinated acetamide moiety attached to a 3-ethoxyphenyl group, contributing to its crystalline form.

Comment on solubility

Solubility of 2-chloro-N-(3-ethoxyphenyl)acetamide

The solubility of 2-chloro-N-(3-ethoxyphenyl)acetamide, with the chemical formula C11H14ClN1O2, can be described as follows:

  • Polarity: This compound possesses polar functional groups due to the presence of the amide and ethoxy groups, which can interact with water molecules, potentially enhancing its solubility in polar solvents.
  • Solvent Interaction: It is expected to have moderate solubility in common organic solvents such as ethanol and methanol, due to its ethoxy substituent.
  • Hydrogen Bonding: The amide group enables hydrogen bonding, which is a key factor in solubility in polar solvents.
  • Temperature Effects: Like many organic compounds, its solubility may increase with temperature, making it more soluble in warmer solvents.

In summary, while 2-chloro-N-(3-ethoxyphenyl)acetamide is likely to be soluble in polar solvents because of its structural features, it may exhibit limited solubility in water. It is always favorable to conduct experimental solubility tests to ascertain precise values since factors like pH and temperature can also significantly influence solubility outcomes.

Interesting facts

Interesting Facts about 2-chloro-N-(3-ethoxyphenyl)acetamide

2-chloro-N-(3-ethoxyphenyl)acetamide is a fascinating compound that lies at the intersection of organic chemistry and pharmacological applications. This compound belongs to the class of acetamides, which are widely recognized for their biological significance. Here are some intriguing aspects of this compound:

  • Therapeutic Potential: Compounds similar to 2-chloro-N-(3-ethoxyphenyl)acetamide have shown promise in the development of new pharmaceuticals, particularly in treating conditions like inflammation and pain.
  • Structure-Activity Relationship: Its structure suggests that the presence of a chloro group and the ethoxyphenyl moiety may contribute to specific biological activities, making it an interesting subject for further study.
  • Synthesis: The synthesis of this compound can be achieved through various methods, often involving the acylation of amines. This highlights the versatility of synthetic organic chemistry techniques.
  • Analytical Techniques: The analysis of 2-chloro-N-(3-ethoxyphenyl)acetamide employs various methods such as NMR and HPLC, providing students with hands-on experience in understanding compounds at a molecular level.
  • Environmental Considerations: As a synthetic chemical, understanding the environmental impact and degradation pathways of compounds like this is vital in modern chemistry, particularly in pharmaceuticals.

As Marie Curie once said, “Nothing in life is to be feared, it is only to be understood.” The study of 2-chloro-N-(3-ethoxyphenyl)acetamide is not just about its chemical composition, but about unlocking the potential benefits it may hold for future scientific advancement.

Synonyms
17641-12-2
m-ACETOPHENETIDIDE, 2-CHLORO-
2-Chloro-m-acetophenetidide
N-Chloroacetyl-m-phenetidide
m-Phenetidine, N-chloroacetyl-
BRN 2693120
DTXSID60170132
1-13-00-00133 (Beilstein Handbook Reference)
DTXCID4092623
2-chloro-N-(3-ethoxyphenyl)acetamide
starbld0012174
orb1985736
MFCD01673050
STK895565
AKOS002339215
ST51066186
Z608582972