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2-chloro-N-(4-ethoxyphenyl)acetamide

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Identification
Molecular formula
C10H12ClNO2
CAS number
120-38-9
IUPAC name
2-chloro-N-(4-ethoxyphenyl)acetamide
State
State

At room temperature, 2-chloro-N-(4-ethoxyphenyl)acetamide is typically a solid as evidenced by its crystalline appearance and relatively low melting point.

Melting point (Celsius)
81.00
Melting point (Kelvin)
354.20
Boiling point (Celsius)
314.40
Boiling point (Kelvin)
587.50
General information
Molecular weight
213.66g/mol
Molar mass
213.6620g/mol
Density
1.2927g/cm3
Appearence

2-chloro-N-(4-ethoxyphenyl)acetamide appears as a white to off-white crystalline solid. It has a distinct crystalline structure, often forming as small, solid particles or powder.

Comment on solubility

Solubility of 2-chloro-N-(4-ethoxyphenyl)acetamide

The solubility of 2-chloro-N-(4-ethoxyphenyl)acetamide can be influenced by a variety of factors including temperature, pH, and the presence of other solvents. In general, this compound is expected to exhibit moderate solubility in organic solvents but lower solubility in water due to its relatively non-polar characteristics.

Key Points on Solubility:

  • Solvent Compatibility: Common organic solvents such as ethanol and dimethyl sulfoxide (DMSO) may dissolve this compound effectively.
  • Temperature Effects: Higher temperatures generally increase solubility for many compounds; thus, heating may improve the dissolution process.
  • pH Sensitivity: Adjusting the pH can impact solubility, particularly if it alters the ionization state of the compound.

In summary, understanding the solubility characteristics of 2-chloro-N-(4-ethoxyphenyl)acetamide is crucial for its application in various fields, particularly in pharmaceutical development and chemical synthesis. As you explore this compound, consider experimenting with different solvents and conditions to fully appreciate its solubility behavior.

Interesting facts

Interesting Facts About 2-chloro-N-(4-ethoxyphenyl)acetamide

2-chloro-N-(4-ethoxyphenyl)acetamide is a fascinating compound that has garnered attention in various fields of research and application. Here are some insightful aspects and fun facts that highlight its significance:

  • Pharmaceutical Relevance: This compound belongs to a class of acetamides that has been studied for potential biological activity, especially in the realm of drug development. Researchers are keen on understanding its pharmacokinetic and pharmacodynamic properties.
  • Mechanism of Action: Some derivatives of acetamides are known to interact with specific biological targets, making compounds like 2-chloro-N-(4-ethoxyphenyl)acetamide significant in the search for new therapeutic agents.
  • Synthetic Pathways: The synthesis of this compound often involves straightforward organic reactions that illustrate fundamental principles of organic chemistry, such as nucleophilic substitution and acylation. This makes it an excellent example for teaching purposes.
  • Versatile Applications: Beyond its pharmaceutical implications, similar compounds have been explored for uses in agrochemicals and as intermediates in organic synthesis. This versatility makes them attractive in both academic and industrial contexts.
  • Research Interest: Studies have indicated that analogs of this compound may possess anti-inflammatory and analgesic properties, contributing to ongoing research aimed at finding effective treatments for various conditions.

In the words of a seasoned chemist, "Understanding the structure-activity relationship of such compounds is vital to unlocking new therapeutic potentials." Such beliefs drive the scientific inquiry surrounding this compound and elevate its status in chemical research.

Overall, 2-chloro-N-(4-ethoxyphenyl)acetamide stands as a noteworthy compound in the vast world of chemistry, inviting exploration and innovation across various scientific disciplines.

Synonyms
2-chloro-N-(4-ethoxyphenyl)acetamide
2153-08-4
2-Chloro-p-acetophenetidide
Acetamide, 2-chloro-N-(4-ethoxyphenyl)-
p-ACETOPHENETIDIDE, 2-CHLORO-
N-(Chloroacetyl)-p-phenetidide
p-Phenetidine, N-chloroacetyl-
MFCD00018908
X55ZN2ADK2
AI3-23575
NSC-46900
Acetamide,2-chloro-N-(4-ethoxyphenyl)-
NSC46900
NSC 46900
BRN 0514356
2-Chloro-N-(4-ethoxy-phenyl)-acetamide
UNII-X55ZN2ADK2
WLN: G1VMR DO2
N-Chloroacetyl-4-ethoxyaniline
alpha-Chloro-p-ethoxyacetanilide
DTXSID80175866
ALBB-002283
STK119119
AKOS000265703
N-(4-Ethoxyphenyl)-2-chloroacetamide
JS-2986
EN300-01572
VU0549360-1
H22012
3-13-00-01059 (Beilstein Handbook Reference)
AP-853/40688228
SR-01000031880
SR-01000031880-1
Z56821912
F9995-0395