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2-chloro-N-(4,5-dichloro-2-fluorophenyl)acetamide

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Identification
Molecular formula
C8H5Cl3FNO
CAS number
247569-50-4
IUPAC name
2-chloro-N-(4,5-dichloro-2-fluoro-phenyl)acetamide
State
State

At room temperature, 2-chloro-N-(4,5-dichloro-2-fluoro-phenyl)acetamide is typically in a solid state. Its structure leads it to form crystalline structures, which are stable under standard conditions.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
259.48g/mol
Molar mass
259.4790g/mol
Density
1.5800g/cm3
Appearence

2-chloro-N-(4,5-dichloro-2-fluoro-phenyl)acetamide is typically a solid at room temperature. Its crystalline form can appear as white to off-white crystals or powder, depending on purity and storage conditions.

Comment on solubility

Solubility of 2-chloro-N-(4,5-dichloro-2-fluoro-phenyl)acetamide

The solubility of 2-chloro-N-(4,5-dichloro-2-fluoro-phenyl)acetamide in various solvents reflects its unique chemical structure and properties. Understanding its solubility is crucial for applications in pharmaceutical formulations and chemical processes. Here are some key points regarding its solubility:

  • Polar Solvents: This compound tends to exhibit limited solubility in polar solvents due to the presence of halogen atoms which can interfere with hydrogen bonding.
  • Non-Polar Solvents: In contrast, it may demonstrate better solubility in non-polar organic solvents, benefiting from van der Waals interactions.
  • Temperature Effects: Increasing temperature generally enhances the solubility of solids; thus, heating the solvent can improve the dissolution of this compound.
  • pH Influence: As an amide, solubility may vary with pH levels, potentially affecting the ionization state of the compound.

In summary, while 2-chloro-N-(4,5-dichloro-2-fluoro-phenyl)acetamide has specific solubility characteristics, it is essential to consider the solvent type and external conditions to achieve optimal dissolution for its intended applications. Always refer to detailed solubility studies for precise data, as environmental factors can greatly influence these observations.

Interesting facts

Interesting Facts about 2-chloro-N-(4,5-dichloro-2-fluoro-phenyl)acetamide

2-chloro-N-(4,5-dichloro-2-fluoro-phenyl)acetamide, a compound of significant interest in the field of medicinal chemistry, is recognized for its unique structure and potential applications in pharmaceuticals.

Key Characteristics:

  • Mechanism of Action: This compound is often studied for its role in inhibiting specific enzymes, making it a potential candidate for drug development.
  • Fluorine Influence: The presence of fluorine atoms in the structure often enhances the metabolic stability of the compound, which is a desirable trait for therapeutic agents.
  • Chlorine Atoms: The chlorinated phenyl group can contribute to the compound's lipophilicity, improving its ability to penetrate biological membranes.

Applications in Research:

This compound has garnered attention for its potential use in:

  • Anticancer Therapy: Researchers are exploring its effectiveness as an anticancer agent.
  • Antimicrobial Properties: Preliminary studies indicate it may exhibit activity against specific bacterial strains.

Quote from Research:

As one researcher noted, “The efficacy of compounds like 2-chloro-N-(4,5-dichloro-2-fluoro-phenyl)acetamide could pave the way for novel treatments in areas previously deemed challenging.”

In exploring its potential, chemists often emphasize the significance of structure-activity relationships, highlighting that small modifications can lead to dramatically different biological effects. The importance of such compounds in drug discovery cannot be overstated, as they contribute to the development of safer and more effective therapies.

Synonyms
2'-Fluoro-2,4',5'-trichloroacetanilide
23554-66-7
BRN 2115447
ACETANILIDE, 2'-FLUORO-2,4',5'-TRICHLORO-
DTXSID90178146
RefChem:315690
DTXCID20100637