Clobenzorex | Solubility of Things

Identification

Molecular formula

C₁₈H₂₀Cl₂NS

CAS number

13364-32-4

IUPAC name

2-chloro-N-[(5-chlorobenzothiophen-3-yl)methyl]-N-ethyl-ethanamine

State

At room temperature, Clobenzorex is typically found in a solid state, specifically in powdered form. It is often stored in a dry environment to maintain its stability.

Melting point (Celsius)

53.00

Melting point (Kelvin)

326.15

Boiling point (Celsius)

456.00

Boiling point (Kelvin)

729.15

General information

Molecular weight

336.33g/mol

Molar mass

296.2110g/mol

Density

1.2043g/cm³

Appearence

Clobenzorex is typically encountered as a crystalline powder. Its appearance can range from white to off-white, often depending on its purity and any formulating agents present.

Comment on solubility

Solubility of 2-chloro-N-[(5-chlorobenzothiophen-3-yl)methyl]-N-ethyl-ethanamine

The solubility of 2-chloro-N-[(5-chlorobenzothiophen-3-yl)methyl]-N-ethyl-ethanamine in various solvents is influenced by its structural characteristics:

Polarity: This compound features both polar and non-polar groups, making it moderately soluble in polar solvents like water, while also exhibiting some solubility in organic solvents, such as ethanol and methanol.
Hydrophobic Interactions: The presence of the chlorobenzothiophen moiety enhances its hydrophobic character, which may limit its solubility in highly polar solvents.
Temperature Effect: Solubility is generally temperature-dependent; thus, increasing the temperature of the solvent can lead to an increase in solubility.
pH Sensitivity: As an amine, the solubility of this compound can also be affected by the pH of the solution, whereby it becomes more soluble in acidic conditions due to protonation.

In summary, while 2-chloro-N-[(5-chlorobenzothiophen-3-yl)methyl]-N-ethyl-ethanamine is expected to show moderate solubility in both polar and non-polar solvents, careful consideration of factors such as solvent choice, temperature, and pH will be essential for achieving optimal dissolution.

Interesting facts

Interesting Facts about 2-chloro-N-[(5-chlorobenzothiophen-3-yl)methyl]-N-ethyl-ethanamine

This compound, known as a derivative of the widely studied class of compounds, exhibits some fascinating characteristics that intrigue chemists and pharmacologists alike. Here are some notable points:

Structural Complexity: The structure of this compound features a chloro substituent and a unique benzothiophene moiety. The presence of such heterocycles often enhances the biological properties of organic compounds.
Applications in Research: Compounds of this nature have been explored for their potential use in pharmaceutical applications, acting as intermediates in the synthesis of various medicinal compounds.
Biological Activity: While specific biological activities may vary, many compounds with similar structures demonstrate a range of effects, including anti-inflammatory and anti-cancer properties.
Chirality Considerations: Depending on the orientation of the groups around the nitrogen atom, versions of this compound may exhibit different biological activities, highlighting the importance of studying stereochemistry in drug design.

As noted by some researchers, "Understanding the interactions of such complex molecules with biological targets is key to the development of new therapeutic agents." This embodies the ongoing pursuit in medicinal chemistry to unlock the potential of interesting structures like 2-chloro-N-[(5-chlorobenzothiophen-3-yl)methyl]-N-ethyl-ethanamine.

In summary, this compound serves as an excellent example of how variations in molecular structure can lead to significant differences in function and application, making it a valuable subject of study for students and scientists alike.