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Chlorphenamine

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Identification
Molecular formula
C16H19ClN2
CAS number
132-22-9
IUPAC name
2-chloro-N-ethyl-N-(2-naphthylmethyl)ethanamine
State
State

Under standard conditions of temperature and pressure, chlorphenamine is a solid compound, typically found as a powder.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
314.00
Boiling point (Kelvin)
587.15
General information
Molecular weight
274.79g/mol
Molar mass
274.8060g/mol
Density
1.0871g/cm3
Appearence

Chlorphenamine is typically encountered as a white crystalline powder. It may also be available as tablets, compressed from this powdered form, intended for oral administration.

Comment on solubility

Solubility of 2-chloro-N-ethyl-N-(2-naphthylmethyl)ethanamine

The solubility of 2-chloro-N-ethyl-N-(2-naphthylmethyl)ethanamine can be influenced by various factors, including its molecular structure and the surrounding medium. This compound, with its complex naphthyl structure, exhibits the following characteristics in terms of solubility:

  • Polarity: The presence of both a chloro group and an ethyl component suggests a moderate level of polarity, which can affect the solubility in polar versus non-polar solvents.
  • Solvent Interaction: It is often soluble in organic solvents such as ethanol and dichloromethane due to its hydrophobic naphthyl group, while demonstrating limited solubility in water.
  • Temperature Dependency: Like many organic compounds, solubility can increase with temperature, indicating that heating the solvent may enhance dissolution.
  • pH Considerations: The environment's pH can also play a role; for example, adjusting pH levels could potentially increase solubility if the molecule can gain or lose protons, affecting its ionic state.

In summary, the solubility of 2-chloro-N-ethyl-N-(2-naphthylmethyl)ethanamine is primarily dependent on its molecular characteristics and the properties of the solvent used. As always, empirical testing is essential to determine solubility accurately in specific conditions.

Interesting facts

Interesting Facts about 2-chloro-N-ethyl-N-(2-naphthylmethyl)ethanamine

2-chloro-N-ethyl-N-(2-naphthylmethyl)ethanamine, commonly referred to in chemical discussions as a versatile amine compound, showcases intriguing properties and potential applications in various fields of chemistry and medicine.

Applications in Research

  • Pharmaceutical Industry: This compound is notable for its role as a potential intermediate in pharmaceutical synthesis, particularly in the development of drugs targeting neurological disorders.
  • Biochemical Studies: As a substrate, it can be utilized to study amine interactions in biological systems, providing insights into receptor binding dynamics.

Chemical Characteristics

This compound features a unique chloro substituent as well as a naphthylmethyl group, contributing to its biological activity and reactivity. The presence of a chlorine atom can significantly influence the compound's lipophilicity, which in turn affects its permeability across cell membranes. As a result:

  • It may exhibit enhanced interactions with lipid environments.
  • It has the potential to serve as a lead compound in drug development because of its distinctive structure.

Safety and Handling

It is crucial to consider the safety measures while working with this compound due to the presence of chlorine. Proper laboratory protocols, including the use of protective equipment, are essential to mitigate risks associated with handling such amines.

Future Directions

As research continues, the future looks bright for 2-chloro-N-ethyl-N-(2-naphthylmethyl)ethanamine. Scientists are keen on exploring:

  • Its potential as a therapeutic agent.
  • New synthetic pathways to enhance yield and reduce costs in its production.
  • Its interactions with various biological targets to uncover novel mechanisms of action.

In summary, the study of 2-chloro-N-ethyl-N-(2-naphthylmethyl)ethanamine holds promising avenues for discovery, making it a compound of interest in the realms of chemistry and medicine.