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Acetochlor

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Identification
Molecular formula
C14H20ClNO2S
CAS number
34256-82-1
IUPAC name
2-chloro-N-ethyl-N-(4-sulfamoylphenyl)acetamide
State
State

Acetochlor is typically found in a liquid state at room temperature.

Melting point (Celsius)
-1.00
Melting point (Kelvin)
272.15
Boiling point (Celsius)
110.00
Boiling point (Kelvin)
383.15
General information
Molecular weight
269.84g/mol
Molar mass
269.1490g/mol
Density
1.1957g/cm3
Appearence

Acetochlor is generally encountered as a colorless liquid. It is characterized by its distinctive sharp odor.

Comment on solubility

Solubility of 2-chloro-N-ethyl-N-(4-sulfamoylphenyl)acetamide

2-chloro-N-ethyl-N-(4-sulfamoylphenyl)acetamide exhibits a complex solubility profile influenced by its functional groups and molecular structure. Understanding its solubility behavior is vital for its application in various fields, including pharmaceuticals and chemical synthesis.

This compound is expected to have the following solubility characteristics:

  • Polar Nature: Due to the presence of the sulfonamide and amide functional groups, the compound is likely to be more soluble in polar solvents such as water.
  • Organic Solvents: It may also dissolve in organic solvents like methanol or ethanol, although the degree of solubility may vary.
  • pH Dependency: The solubility can be significantly influenced by the pH of the solution, particularly because the sulfonamide group can exist in both protonated and deprotonated forms.

In summary, while 2-chloro-N-ethyl-N-(4-sulfamoylphenyl)acetamide demonstrates favorable solubility in polar environments, its behavior in more non-polar media may be limited. Hence, “solubility is key” in determining its applicability and effectiveness in different contexts.

Interesting facts

Exploring 2-chloro-N-ethyl-N-(4-sulfamoylphenyl)acetamide

2-chloro-N-ethyl-N-(4-sulfamoylphenyl)acetamide is a fascinating compound primarily recognized for its potential applications in the realm of pharmaceuticals. This compound is part of the sulfonamide family, which has made significant contributions to the field of medicinal chemistry. Here are some noteworthy facts about this compound:

  • **Origin of Sulfonamides:** The first sulfonamide, prontosil, marked the beginning of modern antibiotics, paving the way for the development of more effective antibacterial agents.
  • **Pharmacological Potential:** Compounds like 2-chloro-N-ethyl-N-(4-sulfamoylphenyl)acetamide are often studied for their ability to inhibit bacterial growth, making them candidates for developing new antimicrobial agents.
  • **Structure-Activity Relationship:** Understanding the structure of this compound, particularly the sulfonamide functional group, helps chemists predict its biological activity and efficacy in medical applications.
  • Derivatives and Variants: By modifying the components of the molecule, scientists can create various derivatives that may enhance specific properties, such as potency or selectivity against particular pathogens.

Moreover, the presence of the chloro and the ethyl groups adds to the compound's structural diversity, which is crucial for optimizing its pharmacokinetic properties. As stated in the world of medicinal chemistry, “modification leads to innovation.” This principle holds true for 2-chloro-N-ethyl-N-(4-sulfamoylphenyl)acetamide as researchers continue to explore its capabilities and implications in drug development.

In summary, 2-chloro-N-ethyl-N-(4-sulfamoylphenyl)acetamide not only embodies the rich history of sulfonamides but also represents a promising avenue for future medicinal discoveries that could potentially lead to new treatments for infectious diseases.

Synonyms
BRN 2700528
ACETANILIDE, 2-CHLORO-N-ETHYL-4'-SULFAMOYL-
2-Chloro-N-ethyl-4'-sulfamoyl-acetanilide
838-16-4
N(sup 4)-Chloroacetyl-N(sup 4)-ethylsulfanilamide
DTXSID60232663
DTXCID90155154