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Chlorphenamine

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Identification
Molecular formula
C16H19ClN
CAS number
113-92-8
IUPAC name
2-chloro-N-ethyl-N-(o-tolylmethyl)ethanamine
State
State

At room temperature, chlorphenamine exists in a solid crystalline state. It does not have a distinct odor and is soluble in organic solvents.

Melting point (Celsius)
48.00
Melting point (Kelvin)
321.15
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.15
General information
Molecular weight
274.82g/mol
Molar mass
274.8220g/mol
Density
1.0132g/cm3
Appearence

Chlorphenamine is typically found as a white to yellow crystalline powder. It is often presented in pharmaceutical formulations, either as tablets, capsules, or syrups. The compound is stable under recommended storage conditions and should be protected from moisture and light to maintain its integrity.

Comment on solubility

Solubility of 2-chloro-N-ethyl-N-(o-tolylmethyl)ethanamine (C16H19ClN)

The solubility of 2-chloro-N-ethyl-N-(o-tolylmethyl)ethanamine can be influenced by various factors including its chemical structure and the surrounding environment. Here are some important points regarding its solubility:

  • Polar vs. Nonpolar: The compound contains a chlorine atom, which introduces a certain level of polarity, yet the presence of the bulky o-tolylmethyl group adds nonpolar characteristics.
  • Solvent Compatibility: It is anticipated that this compound is more soluble in organic solvents such as ethanol or acetone, than in polar solvents like water. This stems from the nonpolar regions of the molecule.
  • Temperature Influence: Generally, increases in temperature may enhance solubility in organic solvents, as higher kinetic energy can break intermolecular forces.
  • Possible Applications: Understanding the solubility can aid in its application in pharmaceutical formulations, where solvent compatibility is crucial.

In conclusion, while exact solubility values may depend on specific experimental conditions, the structural characteristics of 2-chloro-N-ethyl-N-(o-tolylmethyl)ethanamine suggest limited solubility in water and increased solubility in organic solvents.

Interesting facts

Interesting Facts about 2-chloro-N-ethyl-N-(o-tolylmethyl)ethanamine

2-chloro-N-ethyl-N-(o-tolylmethyl)ethanamine, often referred to by its more manageable name, is a fascinating compound in organic chemistry. Here are some compelling insights into this intriguing molecule:

  • Structural Features: This compound has a unique structure characterized by a chloro group, an ethyl group, and a complex tolylmethyl moiety, which contributes to its distinct chemical properties.
  • Pharmacological Potential: Compounds like 2-chloro-N-ethyl-N-(o-tolylmethyl)ethanamine can serve as a starting point in drug discovery, particularly in the development of antidepressants or anxiolytics.
  • Derivatives and Syntheses: The synthesis of this compound often involves multi-step organic reactions, which could include techniques such as alkylation and halogenation, exemplifying the creativity in synthetic organic chemistry.
  • Research Applications: Understanding the behaviors of similar compounds in biological systems can provide crucial insights into their interactions with neurotransmitter receptors in the brain.
  • Safety and Regulation: Due to its chemical nature, this compound may be subject to regulations, particularly in contexts related to pharmaceuticals or controlled substances.

As a chemistry student or an aspiring scientist, one should always consider the broader impact of synthetic compounds such as 2-chloro-N-ethyl-N-(o-tolylmethyl)ethanamine in various fields, including medicine, environmental science, and material science. It serves as a reminder of the interconnectedness of chemistry with real-world applications.

Synonyms
Xylamine
78686-02-9
2-chloro-N-ethyl-N-[(2-methylphenyl)methyl]ethanamine
N-2-Chloroethyl-N-ethyl-2-methylbenzylamine
Benzenemethanamine, N-(2-chloroethyl)-N-ethyl-2-methyl-
N-(2-Chloroethyl)-N-ethyl-2-methybenzenemethanamine
DTXSID10229245
2-Chloro-N-ethyl-N-(2-methylbenzyl)ethan-1-amine
N-(2-Chloroethyl)-N-ethyl-2-methylbenzylamine
starbld0007116
CHEMBL1616379
SCHEMBL13137718
DTXCID30151736
923NT4H8G3
AKOS012693722
Benzylamine, N-(2-chloroethyl)-N-ethyl-o-methyl-
(2-Chloroethyl)(ethyl)[(2-methylphenyl)methyl]amine
N-(2-Chloroethyl)-N-ethyl-2-methylbenzenemethanamine