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Chlorpropham

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Identification
Molecular formula
C10H12ClNO
CAS number
101-21-3
IUPAC name
2-chloro-N-isopropyl-N-phenyl-acetamide
State
State

At room temperature, Chlorpropham is typically a solid.

Melting point (Celsius)
41.00
Melting point (Kelvin)
314.15
Boiling point (Celsius)
144.00
Boiling point (Kelvin)
417.15
General information
Molecular weight
213.67g/mol
Molar mass
213.6880g/mol
Density
1.0500g/cm3
Appearence

Chlorpropham typically appears as a colorless or white crystalline solid.

Comment on solubility

Solubility of 2-chloro-N-isopropyl-N-phenyl-acetamide (C10H12ClNO)

The solubility of 2-chloro-N-isopropyl-N-phenyl-acetamide can be quite intriguing due to its unique structure and functional groups. As a moderately polar compound, it exhibits some interesting solubility characteristics:

  • Solvent Compatibility: This compound is generally more soluble in organic solvents such as ethanol, acetone, and dichloromethane compared to water.
  • Water Solubility: Being a chlorinated amide, its solubility in water is limited. This limitation arises due to the hydrophobic character of the isopropyl and phenyl groups, which outweigh the polar acetamide functional group.
  • Temperature Influence: Solubility can also vary with temperature. Generally, increased temperature can enhance the solubility of organic compounds in solvent mixtures.

In general, 2-chloro-N-isopropyl-N-phenyl-acetamide is more favorable for use in organic syntheses where non-polar or moderately polar solvents are utilized. This reflects the broader trend where organic compounds with multiple non-polar moieties typically exhibit low solubility in water but find good solvation in organic mediums.

Ultimately, understanding the solubility characteristics of such compounds is crucial for their application in various chemical processes.

Interesting facts

Interesting Facts About 2-Chloro-N-Isopropyl-N-Phenyl-Acetamide

2-Chloro-N-isopropyl-N-phenyl-acetamide, commonly recognized for its unique structural characteristics, is a fascinating compound in the realm of organic chemistry. This compound serves several important roles, particularly in the pharmaceutical and agrochemical industries. Here are some notable aspects:

  • Pharmaceutical Relevance: The compound is often explored for its potential therapeutic applications. Derivatives of acetamides are widely studied for their biological activity, including anti-inflammatory and analgesic properties.
  • Structural Importance: The presence of both a chloro group and an isopropyl group in its structure can significantly influence its reactivity and biological interactions. The isopropyl moiety, in particular, often enhances the lipophilicity of compounds, aiding in membrane permeability.
  • Reactivity: Due to the presence of the chloro atom, 2-chloro-N-isopropyl-N-phenyl-acetamide can participate in nucleophilic substitution reactions, making it a valuable intermediate in organic synthesis. This reactivity can pave the way for creating more complex molecules.
  • Research Potential: The ongoing research into acetamide derivatives continues to reveal new mechanisms of action and applications, highlighting the compound's relevance in drug design and discovery. Scientists are continually examining its potential to alleviate various health conditions.

The study of 2-chloro-N-isopropyl-N-phenyl-acetamide not only enriches our understanding of organic synthesis but also opens pathways for innovative medicinal chemistry. As noted by chemists, “Every compound has a story, and this compound is no exception in the chapter of chemical exploration.”

In summary, 2-chloro-N-isopropyl-N-phenyl-acetamide showcases the intricate relationships between structure and function in chemical compounds, allowing scientists to unlock new possibilities in various fields.

Synonyms
propachlor
1918-16-7
2-Chloro-N-isopropylacetanilide
Acilid
Niticid
2-Chloro-N-isopropyl-N-phenylacetamide
Propachlore
Bexton
Nitacid
Prolex
Ramrod
Satecid
Bexton 4L
Kartex A
Ramrod 65
N-Isopropyl-2-chloroacetanilide
Acetamide, 2-chloro-N-(1-methylethyl)-N-phenyl-
2-Chloro-N-(1-methylethyl)-N-phenylacetamide
N-Isopropyl-alpha-chloroacetanilide
2-chloro-N-phenyl-N-propan-2-ylacetamide
Chloressigsaeure-N-isopropylanilid
Caswell No. 194
alpha-Chloro-N-isopropylacetanilide
Propachlor [BSI:ISO]
Propachlor [ISO]
Propachlore [ISO-French]
Ramrod 20G
CP 31393
Acetanilide, 2-chloro-N-isopropyl-
Albrass
Muharicid
Ramrod flowable
Ramrod-atrazine
HSDB 1200
Tripart sentinel
EINECS 217-638-2
EPA Pesticide Chemical Code 019101
BRN 2103903
DTXSID4024274
CHEBI:19503
AI3-51503
alpha-chloro-N-isopropylacetanilid
Chloressigsaeure-N-isopropylanilid [German]
2-chloro-N-phenyl-N-(propan-2-yl)acetamide
PROPACHLOR [MI]
PROPACHLOR [HSDB]
UNII-015443A483
Ramrod flowable (Salt/Mix)
DTXCID504274
N-methylethyl-N-chloroacidobenzene
.alpha.-Chloro-N-isopropylacetanilide
N-Isopropyl-.alpha.-Chloroacetanilide
015443A483
Propachlore (ISO-French)
CAS-1918-16-7
n-isopropyl-a-chloroacetanilide
Prolexpropaclor
Croptex
Atlas orange
Tripart granular
Albras propachlor
SHELL PROPER
Propachlor and atrazine
PROPAFLO-AGRIBEN
2-Chloro-N-isopropyl-N-phenyl-acetamide
Spectrum_001885
SpecPlus_000506
Portman propachlor 50FL
Spectrum2_001842
Spectrum3_000843
Spectrum4_000683
Spectrum5_002002
2ChloroNisopropylacetanilide
NIsopropyl2chloroacetanilide
Chloro-N-isopropylacetanilide
SCHEMBL65571
BSPBio_002425
Isopropyl-2-chloroacetanilide
KBioGR_001145
KBioSS_002415
SPECTRUM330052
MLS002207036
Acetanilide, 2chloroNisopropyl
DivK1c_006602
a-chloro-n-isopropylacetanilide
alphaChloroNisopropylacetanilide
ChloressigsaeureNisopropylanilid
NIsopropylalphachloroacetanilide
SPBio_001624
Propachlor, analytical standard
2-Chloro-N-(1-methylethyl)-N-phenylacetamide (9CI)
2ChloroNisopropylNphenylacetamide
CHEMBL1394829
KBio1_001546
KBio2_002409
KBio2_004977
KBio2_007545
KBio3_001925
2-Chloro-N-isopropyl acetanilide
N-isopropyl-N-phenylchloroacetamide
BAA91816
BCP16676
Tox21_201734
Tox21_303036
CCG-39380
MFCD00078731
STL281680
2ChloroN(1methylethyl)Nphenylacetamide
AKOS001031317
USEPA/OPP Pesticide Code: 19101
Acetamide, 2chloroN(1methylethyl)Nphenyl
NCGC00094539-01
NCGC00094539-02
NCGC00094539-03
NCGC00094539-04
NCGC00094539-05
NCGC00094539-06
NCGC00257041-01
NCGC00259283-01
Propachlor 100 microg/mL in Cyclohexane
AC-19975
SMR000855773
UPCMLD0ENAT0505-1085:001
DB-044776
NS00000323
2ChloroN(1methylethyl)Nphenylacetamide (9CI)
EN300-16862
Propachlor, PESTANAL(R), analytical standard
2-chloro-N-(1-methylethyl)-N-phenylethanamide
C18759
G29613
A813527
SR-01000004720
Q2112916
SR-01000004720-1
BRD-K50343025-001-02-5
Z56800648
F0017-0379
217-638-2