Skip to main content

2-chloro-N-methyl-3-oxo-butanamide

ADVERTISEMENT
Identification
Molecular formula
C5H8ClNO2
CAS number
64927-04-4
IUPAC name
2-chloro-N-methyl-3-oxo-butanamide
State
State

At room temperature, 2-chloro-N-methyl-3-oxo-butanamide is in a solid state. It remains stable under standard conditions, maintaining its solid form without significant sublimation or decomposition.

Melting point (Celsius)
89.00
Melting point (Kelvin)
362.15
Boiling point (Celsius)
280.50
Boiling point (Kelvin)
553.70
General information
Molecular weight
149.57g/mol
Molar mass
149.5700g/mol
Density
1.1654g/cm3
Appearence

2-chloro-N-methyl-3-oxo-butanamide is a solid compound that typically appears as a crystalline substance. The color and texture can vary, but it is often seen as a white or off-white crystal, depending on purity.

Comment on solubility

Solubility of 2-chloro-N-methyl-3-oxo-butanamide

The solubility characteristics of 2-chloro-N-methyl-3-oxo-butanamide are influenced by its molecular structure and functional groups. This compound, which features both a carbonyl and an amide functional group, has specific interactions that dictate its solubility in various solvents.

  • Polar Solvents: It is generally expected that 2-chloro-N-methyl-3-oxo-butanamide will have good solubility in polar solvents such as water or alcohols due to the presence of the polar amide group. The ability to form hydrogen bonds with water can enhance its solubility.
  • Non-polar Solvents: Conversely, this compound may show limited solubility in non-polar solvents. The presence of chlorine and the carbonyl group can contribute to some degree of polarity, making it less favorable for non-polar environments.
  • Temperature Effects: Solubility can also be temperature-dependent. Increased temperatures often enhance solubility, thereby enabling a better dissolution of the compound in polar solvents.

In summary, 2-chloro-N-methyl-3-oxo-butanamide is likely to be more soluble in polar solvents than in non-polar ones, making it a versatile compound in various chemical applications. As always, solubility can be affected by multiple factors, and empirical testing is recommended for precise evaluations.

Interesting facts

Interesting Facts About 2-chloro-N-methyl-3-oxo-butanamide

2-chloro-N-methyl-3-oxo-butanamide is a fascinating compound that falls within the realm of amides and serves various purposes in different scientific fields. Here are some intriguing aspects of this compound:

  • Chemical Applications: This compound is of particular interest in organic synthesis and pharmaceutical development. Its structure allows it to engage in multiple chemical reactions, making it a valuable precursor for various pharmaceuticals and agrochemicals.
  • Mechanism of Action: 2-chloro-N-methyl-3-oxo-butanamide exhibits interesting reactivity due to the presence of the chloro group, which can act as a leaving group in substitution reactions. This makes it a useful intermediate in the synthesis of more complex molecules.
  • Biological Significance: While specific biological functions of this compound are still being researched, many compounds similar in structure to 2-chloro-N-methyl-3-oxo-butanamide are known to exert significant effects in biological systems, potentially serving as enzyme inhibitors or modulators of biochemical pathways.
  • Structure-Activity Relationship (SAR): This compound provides a robust platform for SAR studies, where the modification of functional groups can help predict the compound's activity and efficacy in biological systems.

In conclusion, 2-chloro-N-methyl-3-oxo-butanamide is a compound rich in synthetic potential, playing a significant role in advancing our understanding of organic chemistry and contributing to the development of new therapeutic agents. As research continues, the full spectrum of its capabilities and applications remains an exciting area for study.

Synonyms
2-CHLORO-N-METHYL-3-OXOBUTANAMIDE
4116-10-3
2-Chloro-N-methylacetoacetamide
N-Methyl-2-chloroacetoacetamide
Butanamide, 2-chloro-N-methyl-3-oxo-
BRN 2075916
Acetoacetamide, 2-chloro-N-ethyl-
EINECS 223-907-5
alpha-Chloroacetoacetic acid monoethylamide
alpha-Chloracetessigsaeureaethylamid [German]
DTXSID70884036
alpha-Chloracetessigsaeureaethylamid
DTXCID001023508
2-Chloro-N-methyl-3-oxobutyramide
2-Chloro-N-methyl-3-oxo-butanamide
SCHEMBL2446904
a-chloro-N-methyl-acetoacetamide
N-methyl-alpha-chloracetoacetamide
STL303738
AKOS000271136
AKOS016040107
DB-240124
CS-0117007
NS00048888
EN300-20255